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Studies demonstrating higher pancreatic glucose uptake in patients with newly diagnosed type 1 diabetes than healthy controls. MRI and [¹¹C]methionine and [¹⁸F]FDG positron emission tomograpy images of the abdomen in a patient with newly diagnosed type 1 diabetes. Red color indicates strong, green moderate, and blue weak trapping of the substrate, with color scales maximizing the contrast between tissues. The pancreas shows high [¹¹C] methionine, but low [¹⁸F]FDG uptake. The red spot in the [¹⁸F]FDG image reflects high activity in the kidney, from which [¹⁸F]FDG is excreted to the urine. From the article by Kalliokoski et al., in this issue, pages 1909–1914.