Articles listed in blue may be of special interest to clinicians.

Special Features:

Thomas O. Carpenter

EDITORIAL:Variable Degrees of 1- Hydroxylase Activity—Fine Tuning the Rachitic Rheostat
J Clin Endocrinol Metab 2002 87: 2421-2423 doi:10.1210/jc.87.6.2421 [Full Text] [PDF]  

Xuemei Wang, Martin Y. H. Zhang, Walter L. Miller, and Anthony A. Portale

Novel Gene Mutations in Patients with 1-Hydroxylase Deficiency That Confer Partial Enzyme Activity in Vitro
J Clin Endocrinol Metab 2002 87: 2424-2430 doi:10.1210/jc.87.6.2424 [Abstract] [Full Text] [PDF]  

Roberto Romero, Helena Kuivaniemi, and Gerard Tromp

EDITORIAL:Functional Genomics and Proteomics in Term and Preterm Parturition
J Clin Endocrinol Metab 2002 87: 2431-2434 doi:10.1210/jc.87.6.2431 [Full Text] [PDF]  

E. C. Chan, S. Fraser, S. Yin, G. Yeo, K. Kwek, R. J. Fairclough, and R. Smith

Human Myometrial Genes Are Differentially Expressed in Labor: A Suppression Subtractive Hybridization Study
J Clin Endocrinol Metab 2002 87: 2435-2441 doi:10.1210/jc.87.6.2435 [Abstract] [Full Text] [PDF]  

Aila Tiitinen and Matti Välimäki

CLINICAL CASE SEMINAR:Primary Infertility in 45-Year-Old Man with Untreated 21-Hydroxylase Deficiency: Successful Outcome with Glucocorticoid Therapy
J Clin Endocrinol Metab 2002 87: 2442-2445 doi:10.1210/jc.87.6.2442 [Abstract] [Full Text] [PDF]  

The Impact of the Human Genome on Endocrinology: Special Features:

John P. Bilezikian

From the Editor-in-Chief
J Clin Endocrinol Metab 2002 87: 2446 doi:10.1210/jc.87.6.2446 [Full Text] [PDF]  

John C. Achermann, Gokhan Ozisik, Joshua J. Meeks, and J. Larry Jameson

PERSPECTIVE:Genetic Causes of Human Reproductive Disease
J Clin Endocrinol Metab 2002 87: 2447-2454 doi:10.1210/jc.87.6.2447 [Full Text] [PDF]  

Carl D. Malchoff and Diana M. Malchoff

CLINICAL REVIEW 147:The Genetics of Hereditary Nonmedullary Thyroid Carcinoma
J Clin Endocrinol Metab 2002 87: 2455-2459 doi:10.1210/jc.87.6.2455 [Full Text] [PDF]  

Stuart H. Ralston

PERSPECTIVE:Genetic Control of Susceptibility to Osteoporosis
J Clin Endocrinol Metab 2002 87: 2460-2466 doi:10.1210/jc.87.6.2460 [Abstract] [Full Text] [PDF]  

Suzanne M. Jan De Beur and Michael A. Levine

PERSPECTIVE:Molecular Pathogenesis of Hypophosphatemic Rickets
J Clin Endocrinol Metab 2002 87: 2467-2473 doi:10.1210/jc.87.6.2467 [Full Text] [PDF]  

Barry J. Goldstein

HOT TOPIC:Protein-Tyrosine Phosphatases: Emerging Targets for Therapeutic Intervention in Type 2 Diabetes and Related States of Insulin Resistance
J Clin Endocrinol Metab 2002 87: 2474-2480 doi:10.1210/jc.87.6.2474 [Full Text] [PDF]  

Sophia N. Kalantaridou and George P. Chrousos

CLINICAL REVIEW 148:Monogenic Disorders of Puberty
J Clin Endocrinol Metab 2002 87: 2481-2494 doi:10.1210/jc.87.6.2481 [Full Text] [PDF]  

Richard D. Hockett, Sandra C. Kirkwood, Bruce H. Mitlak, and Willard H. Dere

PERSPECTIVE:Pharmacogenomics in Endocrinology
J Clin Endocrinol Metab 2002 87: 2495-2499 doi:10.1210/jc.87.6.2495 [Full Text] [PDF]  

The Impact of the Human Genome on Endocrinology: Original Articles:

Karla F. S. Melo, Regina M. Martin, Elaine M. F. Costa, Filomena M. Carvalho, Alexander A. Jorge, Ivo J. P. Arnhold, and Berenice B. Mendonca

An Unusual Phenotype of Frasier Syndrome due to IVS9 +4C>T Mutation in the WT1 Gene: Predominantly Male Ambiguous Genitalia and Absence of Gonadal Dysgenesis
J Clin Endocrinol Metab 2002 87: 2500-2505 doi:10.1210/jc.87.6.2500 [Abstract] [Full Text] [PDF]  

J. W. M. Martens, S. Lumbroso, M. Verhoef-Post, V. Georget, A. Richter-Unruh, M. Szarras-Czapnik, T. E. Romer, H. G. Brunner, A. P. N. Themmen, and C. Sultan

Mutant Luteinizing Hormone Receptors in a Compound Heterozygous Patient with Complete Leydig Cell Hypoplasia: Abnormal Processing Causes Signaling Deficiency
J Clin Endocrinol Metab 2002 87: 2506-2513 doi:10.1210/jc.87.6.2506 [Abstract] [Full Text] [PDF]  

Dong Zhao, Dan I. Lebovic, and Robert N. Taylor

Long-Term Progestin Treatment Inhibits RANTES (Regulated on Activation, Normal T Cell Expressed and Secreted) Gene Expression in Human Endometrial Stromal Cells
J Clin Endocrinol Metab 2002 87: 2514-2519 doi:10.1210/jc.87.6.2514 [Abstract] [Full Text] [PDF]  

Hua Wang, Winston S. Chu, Chris Hemphill, and Steven C. Elbein

Human Resistin Gene: Molecular Scanning and Evaluation of Association with Insulin Sensitivity and Type 2 Diabetes in Caucasians
J Clin Endocrinol Metab 2002 87: 2520-2524 doi:10.1210/jc.87.6.2520 [Abstract] [Full Text] [PDF]  

Giuseppe Portella, Stefania Scala, Donata Vitagliano, Giancarlo Vecchio, and Alfredo Fusco

ONYX-015, an E1B Gene-Defective Adenovirus, Induces Cell Death in Human Anaplastic Thyroid Carcinoma Cell Lines
J Clin Endocrinol Metab 2002 87: 2525-2531 doi:10.1210/jc.87.6.2525 [Abstract] [Full Text] [PDF]  

R. Barrio, C. Bellanné-Chantelot, J. C. Moreno, V. Morel, H. Calle, M. Alonso, and C. Mustieles

Nine Novel Mutations in Maturity-Onset Diabetes of the Young (MODY) Candidate Genes in 22 Spanish Families
J Clin Endocrinol Metab 2002 87: 2532-2539 doi:10.1210/jc.87.6.2532 [Abstract] [Full Text] [PDF]  

Makio Shozu, Hiroshi Sumitani, Tomoya Segawa, Hei-Juan Yang, Kouichi Murakami, Tadayuki Kasai, and Masaki Inoue

Overexpression of Aromatase P450 in Leiomyoma Tissue Is Driven Primarily through Promoter I.4 of the Aromatase P450 Gene (CYP19)
J Clin Endocrinol Metab 2002 87: 2540-2548 doi:10.1210/jc.87.6.2540 [Abstract] [Full Text] [PDF]  

Luisella Alberti, Maria Carla Proverbio, Sabine Costagliola, Roberto Romoli, Benedetta Boldrighini, Maria Cristina Vigone, Giovanna Weber, Giuseppe Chiumello, Paolo Beck-Peccoz, and Luca Persani

Germline Mutations of TSH Receptor Gene as Cause of Nonautoimmune Subclinical Hypothyroidism
J Clin Endocrinol Metab 2002 87: 2549-2555 doi:10.1210/jc.87.6.2549 [Abstract] [Full Text] [PDF]  

Songya Pang, Weihua Wang, Barry Rich, Raphael David, Ying Tai Chang, Goldy Carbunaru, Susan E. Myers, A. Forbes Howie, Karen J. Smillie, and J. Ian Mason

A Novel Nonstop Mutation in the Stop Codon and a Novel Missense Mutation in the Type II 3ß-Hydroxysteroid Dehydrogenase (3ß-HSD) Gene Causing, Respectively, Nonclassic and Classic 3ß-HSD Deficiency Congenital Adrenal Hyperplasia
J Clin Endocrinol Metab 2002 87: 2556-2563 doi:10.1210/jc.87.6.2556 [Abstract] [Full Text] [PDF]  

Michael A. Pani, Karoline Regulla, Maria Segni, Stefan Hofmann, Michael Hüfner, Anna Maria Pasquino, Klaus-H. Usadel, and Klaus Badenhoop

A Polymorphism within the Vitamin D-Binding Protein Gene Is Associated with Graves’ Disease but Not with Hashimoto’s Thyroiditis
J Clin Endocrinol Metab 2002 87: 2564-2567 doi:10.1210/jc.87.6.2564 [Abstract] [Full Text] [PDF]  

Maria Halonen, Petra Eskelin, Anne-Grethe Myhre, Jaakko Perheentupa, Eystein S. Husebye, Olle Kämpe, Fredrik Rorsman, Leena Peltonen, Ismo Ulmanen, and Jukka Partanen

AIRE Mutations and Human Leukocyte Antigen Genotypes as Determinants of the Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Phenotype
J Clin Endocrinol Metab 2002 87: 2568-2574 doi:10.1210/jc.87.6.2568 [Abstract] [Full Text] [PDF]  

G. Mazzocchi, L. K. Malendowicz, P. Rebuffat, L. Gottardo, and Gastone G. Nussdorfer

Expression and Function of Vasoactive Intestinal Peptide, Pituitary Adenylate Cyclase-Activating Polypeptide, and Their Receptors in the Human Adrenal Gland
J Clin Endocrinol Metab 2002 87: 2575-2580 doi:10.1210/jc.87.6.2575 [Abstract] [Full Text] [PDF]  

I. Y. H. Mak, J. J. Brosens, M. Christian, F. A. Hills, L. Chamley, L. Regan, and J. O. White

Regulated Expression of Signal Transducer and Activator of Transcription, Stat5, and its Enhancement of PRL Expression in Human Endometrial Stromal Cells in Vitro
J Clin Endocrinol Metab 2002 87: 2581-2588 doi:10.1210/jc.87.6.2581 [Abstract] [Full Text] [PDF]  

D. Söderlund, P. Canto, and J. P. Méndez

Identification of Three Novel Mutations in the KAL1 Gene in Patients with Kallmann Syndrome
J Clin Endocrinol Metab 2002 87: 2589-2592 doi:10.1210/jc.87.6.2589 [Abstract] [Full Text] [PDF]  

Yoshino Kinjo, Nobuyuki Takasu, Ichiro Komiya, Takeaki Tomoyose, Masaki Takara, Tsuyoshi Kouki, Yoshinori Shimajiri, Kouichi Yabiku, and Hiroshi Yoshimura

Remission of Graves’ Hyperthyroidism and A/G Polymorphism at Position 49 in Exon 1 of Cytotoxic T Lymphocyte-Associated Molecule-4 Gene
J Clin Endocrinol Metab 2002 87: 2593-2596 doi:10.1210/jc.87.6.2593 [Abstract] [Full Text] [PDF]  

Ilse Weets, Valerie Siraux, Jean-Claude Daubresse, Ivo H. De Leeuw, Francoise Féry, Bart Keymeulen, Georges Krzentowski, Michel Letiexhe, Chantal Mathieu, Frank Nobels, Raoul Rottiers, André Scheen, Luc Van Gaal, Frans C. Schuit, Bart Van Der Auwera, Mao Rui, Pieter De Pauw, Leonard Kaufman, and Frans K. Gorus

Relation between Disease Phenotype and HLA-DQ Genotype in Diabetic Patients Diagnosed in Early Adulthood
J Clin Endocrinol Metab 2002 87: 2597-2605 doi:10.1210/jc.87.6.2597 [Abstract] [Full Text] [PDF]  

Lema Haddad, Julie C. Evans, Neda Gharani, Carole Robertson, Karen Rush, Steven Wiltshire, Timothy M. Frayling, Terence J. Wilkin, Andrew Demaine, Ann Millward, Andrew T. Hattersley, Gerry Conway, Nancy J. Cox, Graeme I. Bell, Steve Franks, and Mark I. McCarthy

Variation within the Type 2 Diabetes Susceptibility Gene Calpain-10 and Polycystic Ovary Syndrome
J Clin Endocrinol Metab 2002 87: 2606-2610 doi:10.1210/jc.87.6.2606 [Abstract] [Full Text] [PDF]  

Chantal Lutfallah, Weihua Wang, J. Ian Mason, Ying Tai Chang, Anzar Haider, Barry Rich, Mariano Castro-Magana, Kenneth C. Copeland, Raphael David, and Songya Pang

Newly Proposed Hormonal Criteria via Genotypic Proof for Type II 3ß-Hydroxysteroid Dehydrogenase Deficiency
J Clin Endocrinol Metab 2002 87: 2611-2622 doi:10.1210/jc.87.6.2611 [Abstract] [Full Text] [PDF]  

Yvonne Lundberg Giwercman, Agneta Nordenskjöld, E. Martin Ritzén, Karl Olof Nilsson, Sten-A. Ivarsson, Ulla Grandell, and Anna Wedell

An Androgen Receptor Gene Mutation (E653K) in a Family with Congenital Adrenal Hyperplasia due to Steroid 21-Hydroxylase Deficiency as well as in Partial Androgen Insensitivity
J Clin Endocrinol Metab 2002 87: 2623-2628 doi:10.1210/jc.87.6.2623 [Abstract] [Full Text] [PDF]  

Hongbo Wang, Yan Wen, Stephen Mooney, Barry Behr, and Mary Lake Polan

Phospholipase A₂ and Cyclooxygenase Gene Expression in Human Preimplantation Embryos
J Clin Endocrinol Metab 2002 87: 2629-2634 doi:10.1210/jc.87.6.2629 [Abstract] [Full Text] [PDF]  

Márta Korbonits, Harvinder S. Chahal, Gregory Kaltsas, Suzanne Jordan, Yulduz Urmanova, Zamira Khalimova, Philip E. Harris, William E. Farrell, Francois-Xavier Claret, and Ashley B. Grossman

Expression of Phosphorylated p27^Kip1 Protein and Jun Activation Domain-Binding Protein 1 in Human Pituitary Tumors
J Clin Endocrinol Metab 2002 87: 2635-2643 doi:10.1210/jc.87.6.2635 [Abstract] [Full Text] [PDF]  

Stephanie A. Pangas, Alfred W. Rademaker, David A. Fishman, and Teresa K. Woodruff

Localization of the Activin Signal Transduction Components in Normal Human Ovarian Follicles: Implications for Autocrine and Paracrine Signaling in the Ovary
J Clin Endocrinol Metab 2002 87: 2644-2657 doi:10.1210/jc.87.6.2644 [Abstract] [Full Text] [PDF]  

Alessandra Vottero, Tomoshige Kino, Herve Combe, Pierre Lecomte, and George P. Chrousos

A Novel, C-Terminal Dominant Negative Mutation of the GR Causes Familial Glucocorticoid Resistance through Abnormal Interactions with p160 Steroid Receptor Coactivators
J Clin Endocrinol Metab 2002 87: 2658-2667 doi:10.1210/jc.87.6.2658 [Abstract] [Full Text] [PDF]  

Satomi Koyama, Takio Toyoura, Sumitaka Saisho, Kazuhiko Shimozawa, and Junichi Yata

Genetic Analysis of Japanese Patients with 21-Hydroxylase Deficiency: Identification of a Patient with a New Mutation of a Homozygous Deletion of Adenine at Codon 246 and Patients without Demonstrable Mutations within the Structural Gene for CYP21
J Clin Endocrinol Metab 2002 87: 2668-2673 doi:10.1210/jc.87.6.2668 [Abstract] [Full Text] [PDF]  

Y. Michael Chau, Susan Pando, and Hugh S. Taylor

HOXA11 Silencing and Endogenous HOXA11 Antisense Ribonucleic Acid in the Uterine Endometrium
J Clin Endocrinol Metab 2002 87: 2674-2680 doi:10.1210/jc.87.6.2674 [Abstract] [Full Text] [PDF]  

Terumasa Nagase, Takehiko Murakami, Toshihiko Tsukada, Ryuichi Kitamura, Noriko Chikatsu, Hiroki Takeo, Nobuki Takata, Hiroko Yasuda, Seiji Fukumoto, Yuji Tanaka, Naokazu Nagata, Ken Yamaguchi, Takuhiko Akatsu, and Michiko Yamamoto

A Family of Autosomal Dominant Hypocalcemia with a Positive Correlation between Serum Calcium and Magnesium: Identification of a Novel Gain of Function Mutation (Ser⁸²⁰Phe) in the Calcium-Sensing Receptor
J Clin Endocrinol Metab 2002 87: 2681-2687 doi:10.1210/jc.87.6.2681 [Abstract] [Full Text] [PDF]  

Jeremy J. O. Turner, Poloko D. Leotlela, Anna A. J. Pannett, Simon A. Forbes, J. H. Duncan Bassett, Brian Harding, Paul T. Christie, David Bowen-Jones, Sian Ellard, Andrew Hattersley, Charles E. Jackson, Richard Pope, Oliver W. Quarrell, Richard Trembath, and Rajesh V. Thakker

Frequent Occurrence of an Intron 4 Mutation in Multiple Endocrine Neoplasia Type 1
J Clin Endocrinol Metab 2002 87: 2688-2693 doi:10.1210/jc.87.6.2688 [Abstract] [Full Text] [PDF]  

Shih-Hua Lin, Daniel G. Bichet, Sei Sasaki, Michio Kuwahara, Marie-Francoise Arthus, Michele Lonergan, and Yuh-Feng Lin

Two Novel Aquaporin-2 Mutations Responsible for Congenital Nephrogenic Diabetes Insipidus in Chinese Families
J Clin Endocrinol Metab 2002 87: 2694-2700 doi:10.1210/jc.87.6.2694 [Abstract] [Full Text] [PDF]  

Odile Paulmyer-Lacroix, Sandrine Boullu, Charles Oliver, Marie-Christine Alessi, and Michel Grino

Expression of the mRNA Coding for 11ß-Hydroxysteroid Dehydrogenase Type 1 in Adipose Tissue from Obese Patients: An in Situ Hybridization Study
J Clin Endocrinol Metab 2002 87: 2701-2705 doi:10.1210/jc.87.6.2701 [Abstract] [Full Text] [PDF]  

Philippa T. K. Saunders, Michael R. Millar, Sheila Macpherson, D. Stewart Irvine, Nigel P. Groome, Lee R. Evans, Richard M. Sharpe, and Graeme A. Scobie

ERß1 and the ERß2 Splice Variant (ERßcx/ß2) Are Expressed in Distinct Cell Populations in the Adult Human Testis
J Clin Endocrinol Metab 2002 87: 2706-2715 doi:10.1210/jc.87.6.2706 [Abstract] [Full Text] [PDF]  

Rapid Communications:

Anke Hinney, Anne Hoch, Frank Geller, Helmut Schäfer, Wolfgang Siegfried, Hanspeter Goldschmidt, Helmut Remschmidt, and Johannes Hebebrand

Ghrelin Gene: Identification of Missense Variants and a Frameshift Mutation in Extremely Obese Children and Adolescents and Healthy Normal Weight Students
J Clin Endocrinol Metab 2002 87: 2716 doi:10.1210/jc.87.6.2716 [Abstract] [Full Text] [PDF]  

Nicolette Arends, Linda Johnston, Anita Hokken-Koelega, Cornelia van Duijn, Maria de Ridder, Martin Savage, and Adrian Clark

Polymorphism in the IGF-I Gene: Clinical Relevance for Short Children Born Small for Gestational Age (SGA)
J Clin Endocrinol Metab 2002 87: 2720 doi:10.1210/jc.87.6.2720 [Abstract] [Full Text] [PDF]  

P. J. English, M. A. Ghatei, I. A. Malik, S. R. Bloom, and J. P. H. Wilding

Food Fails to Suppress Ghrelin Levels in Obese Humans
J Clin Endocrinol Metab 2002 87: 2984 doi:10.1210/jc.87.6.2984 [Abstract] [Full Text] [PDF]  

Sharmilee Gnanapavan, Blerina Kola, Stephen A. Bustin, Damian G. Morris, Patrick McGee, Peter Fairclough, Satya Bhattacharya, Robert Carpenter, Ashley B. Grossman, and Márta Korbonits

The Tissue Distribution of the mRNA of Ghrelin and Subtypes of Its Receptor, GHS-R, in Humans
J Clin Endocrinol Metab 2002 87: 2988 doi:10.1210/jc.87.6.2988 [Abstract] [Full Text] [PDF]  

Endocrine Care:

S. Ezzat, S. Fear, R.-C. Gaillard, C. Gayle, H. Landy, S. Marcovitz, T. Mattioni, S. Nussey, A. Rees, and E. Svanberg

Gender-Specific Responses of Lean Body Composition and Non-Gender-Specific Cardiac Function Improvement after GH Replacement in GH-Deficient Adults
J Clin Endocrinol Metab 2002 87: 2725-2733 doi:10.1210/jc.87.6.2725 [Abstract] [Full Text] [PDF]  

Marla Chellakooty, Lillian Skibsted, Sven O. Skouby, Anna-Maria Andersson, Jørgen H. Petersen, Katharina M. Main, Niels E. Skakkebæk, and Anders Juul

Longitudinal Study of Serum Placental GH in 455 Normal Pregnancies: Correlation to Gestational Age, Fetal Gender, and Weight
J Clin Endocrinol Metab 2002 87: 2734-2739 doi:10.1210/jc.87.6.2734 [Abstract] [Full Text] [PDF]  

Mohamad Maghnie, Francesco Cavigioli, Carmine Tinelli, Michele Autelli, Maurizio Aricò, Gianluca Aimaretti, and Ezio Ghigo

GHRH Plus Arginine in the Diagnosis of Acquired GH Deficiency of Childhood-Onset
J Clin Endocrinol Metab 2002 87: 2740-2744 doi:10.1210/jc.87.6.2740 [Abstract] [Full Text] [PDF]  

Warrick J. Inder and Penny J. Hunt

Glucocorticoid Replacement in Pituitary Surgery: Guidelines for Perioperative Assessment and Management
J Clin Endocrinol Metab 2002 87: 2745-2750 doi:10.1210/jc.87.6.2745 [Abstract] [Full Text] [PDF]  

Jennifer D. Wallace, Winsome J. Abbott-Johnson, Darrell H. G. Crawford, Ross Barnard, Julia M. Potter, and Ross C. Cuneo

GH Treatment in Adults with Chronic Liver Disease: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Study
J Clin Endocrinol Metab 2002 87: 2751-2759 doi:10.1210/jc.87.6.2751 [Abstract] [Full Text] [PDF]  

T. Ueland, J. Bollerslev, A. Flyvbjerg, T. B. Hansen, N. Vahl, and L. Mosekilde

Effects of 12 Months of GH Treatment on Cortical and Trabecular Bone Content of IGFs and OPG in Adults with Acquired GH Deficiency: A Double-Blind, Randomized, Placebo-Controlled Study
J Clin Endocrinol Metab 2002 87: 2760-2763 doi:10.1210/jc.87.6.2760 [Abstract] [Full Text] [PDF]  

Miyao Matsubara, Shoji Maruoka, and Shinji Katayose

Decreased Plasma Adiponectin Concentrations in Women with Dyslipidemia
J Clin Endocrinol Metab 2002 87: 2764-2769 doi:10.1210/jc.87.6.2764 [Abstract] [Full Text] [PDF]  

Karen K. Miller, Beverly M. K. Biller, Joan Hier, Elizabeth Arena, and Anne Klibanski

Androgens and Bone Density in Women with Hypopituitarism
J Clin Endocrinol Metab 2002 87: 2770-2776 doi:10.1210/jc.87.6.2770 [Abstract] [Full Text] [PDF]  

Becky A. Kaufman, Michelle P. Warren, Jennifer E. Dominguez, Jack Wang, Steven B. Heymsfield, and Richard N. Pierson

Bone Density and Amenorrhea in Ballet Dancers Are Related to a Decreased Resting Metabolic Rate and Lower Leptin Levels
J Clin Endocrinol Metab 2002 87: 2777-2783 doi:10.1210/jc.87.6.2777 [Abstract] [Full Text] [PDF]  

Yoshinori Miyazaki, Archana Mahankali, Masafumi Matsuda, Srikanth Mahankali, Jean Hardies, Kenneth Cusi, Lawrence J. Mandarino, and Ralph A. DeFronzo

Effect of Pioglitazone on Abdominal Fat Distribution and Insulin Sensitivity in Type 2 Diabetic Patients
J Clin Endocrinol Metab 2002 87: 2784-2791 doi:10.1210/jc.87.6.2784 [Abstract] [Full Text] [PDF]  

Norman H. Bell, John P. Bilezikian, Henry G. Bone III, Amarjot Kaur, Adele Maragoto, and Arthur C. Santora

Alendronate Increases Bone Mass and Reduces Bone Markers in Postmenopausal African-American Women
J Clin Endocrinol Metab 2002 87: 2792-2797 doi:10.1210/jc.87.6.2792 [Abstract] [Full Text] [PDF]  

Claus Højbjerg Gravholt, Anna Lis Lauridsen, Kim Brixen, Leif Mosekilde, Lene Heickendorff, and Jens Sandahl Christiansen

Marked Disproportionality in Bone Size and Mineral, and Distinct Abnormalities in Bone Markers and Calcitropic Hormones in Adult Turner Syndrome: A Cross-Sectional Study
J Clin Endocrinol Metab 2002 87: 2798-2808 doi:10.1210/jc.87.6.2798 [Abstract] [Full Text] [PDF]  

Kamala Guttikonda, John R. Burgess, Kristen Hynes, Steven Boyages, Karen Byth, and V. Parameswaran

Recurrent Iodine Deficiency in Tasmania, Australia: A Salutary Lesson in Sustainable Iodine Prophylaxis and Its Monitoring
J Clin Endocrinol Metab 2002 87: 2809-2815 doi:10.1210/jc.87.6.2809 [Abstract] [Full Text] [PDF]  

Other Original Articles:

Renée F. Johnson, Carolyn M. Mitchell, Warwick B. Giles, William A. Walters, and Tamas Zakar

The in Vivo Control of Prostaglandin H Synthase-2 Messenger Ribonucleic Acid Expression in the Human Amnion at Parturition
J Clin Endocrinol Metab 2002 87: 2816-2823 doi:10.1210/jc.87.6.2816 [Abstract] [Full Text] [PDF]  

Svetlana Lajic, Séverine Clauin, Tiina Robins, Patrick Vexiau, Hélène Blanché, Christine Bellanne-Chantelot, and Anna Wedell

Novel Mutations in CYP21 Detected in Individuals with Hyperandrogenism
J Clin Endocrinol Metab 2002 87: 2824-2829 doi:10.1210/jc.87.6.2824 [Abstract] [Full Text] [PDF]  

Tsuyoshi Nakanishi, Junya Kohroki, Shizuko Suzuki, Junichi Ishizaki, Youhei Hiromori, Shinri Takasuga, Norio Itoh, Yoshiteru Watanabe, Naoki Utoguchi, and Keiichi Tanaka

Trialkyltin Compounds Enhance Human CG Secretion and Aromatase Activity in Human Placental Choriocarcinoma Cells
J Clin Endocrinol Metab 2002 87: 2830-2837 doi:10.1210/jc.87.6.2830 [Abstract] [Full Text] [PDF]  

Vicki L. Clifton, Euan M. Wallace, and Roger Smith

Short-Term Effects of Glucocorticoids in the Human Fetal-Placental Circulation in Vitro
J Clin Endocrinol Metab 2002 87: 2838-2842 doi:10.1210/jc.87.6.2838 [Abstract] [Full Text] [PDF]  

G. Serviddio, G. Loverro, M. Vicino, F. Prigigallo, I. Grattagliano, E. Altomare, and G. Vendemiale

Modulation of Endometrial Redox Balance during the Menstrual Cycle: Relation with Sex Hormones
J Clin Endocrinol Metab 2002 87: 2843-2848 doi:10.1210/jc.87.6.2843 [Abstract] [Full Text] [PDF]  

Noriko Yamamoto, Lane K. Christenson, Jan M. MCAllister, and Jerome F. Strauss, III

Growth Differentiation Factor-9 Inhibits 3'5'-Adenosine Monophosphate-Stimulated Steroidogenesis in Human Granulosa and Theca Cells
J Clin Endocrinol Metab 2002 87: 2849-2856 doi:10.1210/jc.87.6.2849 [Abstract] [Full Text] [PDF]  

Vincenzo Rochira, Antonio Balestrieri, Marco Faustini-Fustini, Stefano Borgato, Paolo Beck-Peccoz, and Cesare Carani

Pituitary Function in a Man with Congenital Aromatase Deficiency: Effect of Different Doses of Transdermal E2 on Basal and Stimulated Pituitary Hormones
J Clin Endocrinol Metab 2002 87: 2857-2862 doi:10.1210/jc.87.6.2857 [Abstract] [Full Text] [PDF]  

Johan Svensson, Johannes D. Veldhuis, Ali Iranmanesh, Bengt-Åke Bengtsson, and Gudmundur Johannsson

Increased Orderliness of Growth Hormone (GH) Secretion in GH-Deficient Adults with Low Serum Insulin-Like Growth Factor I
J Clin Endocrinol Metab 2002 87: 2863-2869 doi:10.1210/jc.87.6.2863 [Abstract] [Full Text] [PDF]  

Lourdes Ibáñez, Carme Valls, Angela Ferrer, Ken Ong, David B. Dunger, and Francis de Zegher

Additive Effects of Insulin-Sensitizing and Anti-Androgen Treatment in Young, Nonobese Women with Hyperinsulinism, Hyperandrogenism, Dyslipidemia, and Anovulation
J Clin Endocrinol Metab 2002 87: 2870-2874 doi:10.1210/jc.87.6.2870 [Abstract] [Full Text] [PDF]  

Johan Verhaeghe, Axelle Pintiaux, Erik van Herck, Georges Hennen, Jean-Michel Foidart, and Ahmed Igout

Placental GH, IGF-I, IGF-Binding Protein-1, and Leptin during a Glucose Challenge Test in Pregnant Women: Relation with Maternal Body Weight, Glucose Tolerance, and Birth Weight
J Clin Endocrinol Metab 2002 87: 2875-2882 doi:10.1210/jc.87.6.2875 [Abstract] [Full Text] [PDF]  

Steven Grinspoon, Lisa Thomas, Karen Miller, David Herzog, and Anne Klibanski

Effects of Recombinant Human IGF-I and Oral Contraceptive Administration on Bone Density in Anorexia Nervosa
J Clin Endocrinol Metab 2002 87: 2883-2891 doi:10.1210/jc.87.6.2883 [Abstract] [Full Text] [PDF]  

Urszula S. Masiukiewicz, MaryAnn Mitnick, Barbara I. Gulanski, and Karl L. Insogna

Evidence that the IL-6/IL-6 Soluble Receptor Cytokine System Plays a Role in the Increased Skeletal Sensitivity to PTH in Estrogen-Deficient Women
J Clin Endocrinol Metab 2002 87: 2892-2898 doi:10.1210/jc.87.6.2892 [Abstract] [Full Text] [PDF]  

G. I. Uwaifo, S. J. Parikh, M. Keil, J. Elberg, J. Chin, and J. A. Yanovski

Comparison of Insulin Sensitivity, Clearance, and Secretion Estimates Using Euglycemic and Hyperglycemic Clamps in Children
J Clin Endocrinol Metab 2002 87: 2899-2905 doi:10.1210/jc.87.6.2899 [Abstract] [Full Text] [PDF]  

Akira Katsuki, Yasuhiro Sumida, Esteban C. Gabazza, Shuichi Murashima, Hideki Urakawa, Kohei Morioka, Nagako Kitagawa, Takashi Tanaka, Rika Araki-Sasaki, Yasuko Hori, Kaname Nakatani, Yutaka Yano, and Yukihiko Adachi

QUICKI Is Useful for Following Improvements in Insulin Sensitivity after Therapy in Patients with Type 2 Diabetes Mellitus
J Clin Endocrinol Metab 2002 87: 2906-2908 doi:10.1210/jc.87.6.2906 [Abstract] [Full Text] [PDF]  

Maki Shintani, Hiroshi Ikegami, Tomomi Fujisawa, Yoshihiko Kawaguchi, Mitsuru Ohishi, Tomohiro Katsuya, Jitsuo Higaki, Kazuaki Shimamoto, and Toshio Ogihara

Leptin Gene Polymorphism Is Associated with Hypertension Independent of Obesity
J Clin Endocrinol Metab 2002 87: 2909-2912 doi:10.1210/jc.87.6.2909 [Abstract] [Full Text] [PDF]  

Johannes Pleiner, Georg Schaller, Friedrich Mittermayer, Michaela Bayerle-Eder, Michael Roden, and Michael Wolzt

FFA-Induced Endothelial Dysfunction Can Be Corrected by Vitamin C
J Clin Endocrinol Metab 2002 87: 2913-2917 doi:10.1210/jc.87.6.2913 [Abstract] [Full Text] [PDF]  

Margaret O. Sowell, Nitai Mukhopadhyay, Patrizia Cavazzoni, Sudha Shankar, Helmut O. Steinberg, Alan Breier, Charles M. Beasley, Jr, and Jamie Dananberg

Hyperglycemic Clamp Assessment of Insulin Secretory Responses in Normal Subjects Treated with Olanzapine, Risperidone, or Placebo
J Clin Endocrinol Metab 2002 87: 2918-2923 doi:10.1210/jc.87.6.2918 [Abstract] [Full Text] [PDF]  

Sam Mesiano, Eng-Cheng Chan, John T. Fitter, Kenneth Kwek, George Yeo, and Roger Smith

Progesterone Withdrawal and Estrogen Activation in Human Parturition Are Coordinated by Progesterone Receptor A Expression in the Myometrium
J Clin Endocrinol Metab 2002 87: 2924-2930 doi:10.1210/jc.87.6.2924 [Abstract] [Full Text] [PDF]  

Zida Wu, Martin Bidlingmaier, Changlu Liu, Errol B. De Souza, Matthias Tschöp, Katherine M. Morrison, and Christian J. Strasburger

Quantification of the Soluble Leptin Receptor in Human Blood by Ligand-Mediated Immunofunctional Assay
J Clin Endocrinol Metab 2002 87: 2931-2939 doi:10.1210/jc.87.6.2931 [Abstract] [Full Text] [PDF]  

Giovambattista Desideri, Maria Contina Marinucci, Gianluca Tomassoni, Pier Giorgio Masci, Anna Santucci, and Claudio Ferri

Vitamin E Supplementation Reduces Plasma Vascular Cell Adhesion Molecule-1 and von Willebrand Factor Levels and Increases Nitric Oxide Concentrations in Hypercholesterolemic Patients
J Clin Endocrinol Metab 2002 87: 2940-2945 doi:10.1210/jc.87.6.2940 [Abstract] [Full Text] [PDF]  

Bertalan Dudás and István Merchenthaler

Close Juxtapositions between LHRH Immunoreactive Neurons and Substance P Immunoreactive Axons in the Human Diencephalon
J Clin Endocrinol Metab 2002 87: 2946-2953 doi:10.1210/jc.87.6.2946 [Abstract] [Full Text] [PDF]  

Graham J. Burton, Adrian L. Watson, Joanne Hempstock, Jeremy N. Skepper, and Eric Jauniaux

Uterine Glands Provide Histiotrophic Nutrition for the Human Fetus during the First Trimester of Pregnancy
J Clin Endocrinol Metab 2002 87: 2954-2959 doi:10.1210/jc.87.6.2954 [Abstract] [Full Text] [PDF]  

Christopher W. Gregory, Elizabeth M. Wilson, K. B. C. Apparao, Ruth A. Lininger, William R. Meyer, Ania Kowalik, Marc A. Fritz, and Bruce A. Lessey

Steroid Receptor Coactivator Expression throughout the Menstrual Cycle in Normal and Abnormal Endometrium
J Clin Endocrinol Metab 2002 87: 2960-2966 doi:10.1210/jc.87.6.2960 [Abstract] [Full Text] [PDF]  

Ulrika Segersten, Pamela Correa, Martin Hewison, Per Hellman, Henning Dralle, Tobias Carling, Göran Åkerström, and Gunnar Westin

25-Hydroxyvitamin D₃-1-Hydroxylase Expression in Normal and Pathological Parathyroid Glands
J Clin Endocrinol Metab 2002 87: 2967-2972 doi:10.1210/jc.87.6.2967 [Abstract] [Full Text] [PDF]  

L. F. G. Silveira, P. M. Stewart, M. Thomas, D. A. Clark, P. M. G. Bouloux, and G. S. MacColl

Novel Homozygous Splice Acceptor Site GnRH Receptor (GnRHR) Mutation: Human GnRHR "Knockout"
J Clin Endocrinol Metab 2002 87: 2973-2977 doi:10.1210/jc.87.6.2973 [Abstract] [Full Text] [PDF]  

Lorraine E. L. Katz, Diva D. DeLeón, Hui Zhao, and Abbas F. Jawad

Free and Total Insulin-Like Growth Factor (IGF)-I Levels Decline during Fasting: Relationships with Insulin and IGF-Binding Protein-1
J Clin Endocrinol Metab 2002 87: 2978-2983 doi:10.1210/jc.87.6.2978 [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Edward W. Hillhouse and Emmanouil Karteris

Expression of Multiple Corticotropin-Releasing Hormone Receptors in the Human Heart
J Clin Endocrinol Metab 2002 87: 2992 doi:10.1210/jc.87.6.2992 [Full Text] [PDF]  

Yuichiro Kimura, Kazuhiro Takahashi, Kazuhito Totsune, Yasunari Muramatsu, Chika Kaneko, Andrew D. Darnel, Takashi Suzuki, Masahito Ebina, Toshihiro Nukiwa, and Hironobu Sasano

Authors’ Response: Expression of Multiple Corticotropin-Releasing Hormone Receptors in the Human Heart
J Clin Endocrinol Metab 2002 87: 2992a-2993a doi:10.1210/jc.87.6.2992-a [Full Text] [PDF]  

Robert L. Rosenfield

Serum Cortisol and 17-Hydroxyprogesterone Concentrations in Children with Classic Congenital Adrenal Hyperplasia
J Clin Endocrinol Metab 2002 87: 2993 doi:10.1210/jc.87.6.2993 [Full Text] [PDF]  

Evangelia Charmandari

Author’s Response: Serum Cortisol and 17-Hydroxyprogesterone Concentrations in Children with Classic Congenital Adrenal Hyperplasia
J Clin Endocrinol Metab 2002 87: 2993a doi:10.1210/jc.87.6.2993-a [Full Text] [PDF]  

Bridget E. Busuttil and Albert G. Frauman

TSH Receptor Expression in Cardiac Muscle Tissue
J Clin Endocrinol Metab 2002 87: 2994 doi:10.1210/jc.87.6.2994 [Full Text] [PDF]  

Peter Igaz, Attila Patócs, Károly Rácz, Izabella Klein, András Váradi, and Olga Ésik

Occurrence of Pheochromocytoma in a MEN2A Family with Codon 609 Mutation of the RET Protooncogene
J Clin Endocrinol Metab 2002 87: 2994a doi:10.1210/jc.87.6.2994-a [Full Text] [PDF]  

Announcements:

STADY III: International Symposium on Signal Transduction in Health and Disease, Tel Aviv, Israel; October 1–4, 2002
J Clin Endocrinol Metab 2002 87: 2580 doi:10.1210/jc.87.6.2580 [Full Text] [PDF]  

First International Symposium on Insulin Action, Insulin Resistance, Inflammation, and Atherosclerosis, Niagara Falls, New York; September 20–22, 2002
J Clin Endocrinol Metab 2002 87: 2605 doi:10.1210/jc.87.6.2605 [Full Text] [PDF]  

Massachusetts General Hospital Reproductive Endocrine Unit
J Clin Endocrinol Metab 2002 87: 2628 doi:10.1210/jc.87.6.2628 [Full Text] [PDF]  

Fifth International Congress, International Society for Neuroimmunomodulation, Le Corum, Montpellier, France; September 9–11, 2002
J Clin Endocrinol Metab 2002 87: 2687 doi:10.1210/jc.87.6.2687 [Full Text] [PDF]  

Second International Symposium on Progestins, Progesterone Receptor Modulators and Progesterone Antagonists, Siena, Italy; November 20–23, 2002. www.unisi.it/eventi/progestins
J Clin Endocrinol Metab 2002 87: 2776 doi:10.1210/jc.87.6.2776 [Full Text] [PDF]  

Fifth Annual Scientific Forum, Southeast Lipid Association, Williamsburg, Virginia; August 2–4, 2002
J Clin Endocrinol Metab 2002 87: 2808 doi:10.1210/jc.87.6.2808 [Full Text] [PDF]  

Second Transplant Bone Disease Meeting (TBDM 2002) [satellite of the XIX International Congress of the Transplantation Society], Buenos Aires, Argentina; August 16–17, 2002
J Clin Endocrinol Metab 2002 87: 2842 doi:10.1210/jc.87.6.2842 [Full Text] [PDF]  

Ninth International Congress on Obesity, Hotel Transamérica, São Paulo, Brazil; August 24–29, 2002
J Clin Endocrinol Metab 2002 87: 2869 doi:10.1210/jc.87.6.2869 [Full Text] [PDF]  

Research Resources:

Endocrine-Related Resources from the National Institutes of Health
J Clin Endocrinol Metab 2002 87: 2995-2997 doi:10.1210/jc.87.6.2995 [Full Text] [PDF]  

National Hormone & Peptide Program - NIDDK: Recombinant Hormones, Hypothalamic Peptides & Other Hormones, Antisera, Reagents, & Hormone Assay Services Available
J Clin Endocrinol Metab 2002 87: 2998-3000 doi:10.1210/jc.87.6.2998 [Full Text] [PDF]  

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