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Contents: Volume 84, Issue 4   [Index by Author]       Other Issues:  
       Special Articles
       From the Clinical Research Centers
       Original Studies
       Rapid Communications
       Letters to the Editor
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Articles listed in blue may be of special interest to clinicians.

Special Articles:

Richard J. Mahler and Michael L. Adler
CLINICAL REVIEW 102: Type 2 Diabetes Mellitus: Update on Diagnosis, Pathophysiology, and Treatment
J Clin Endocrinol Metab 1999 84: 1165-1171. [Full Text]  

Arlan L. Rosenbloom
EDITORIAL: A Mathematical Model for Predicting Growth Response to Growth Hormone Replacement Therapy—A Useful Clinical Tool or an Intellectual Exercise?
J Clin Endocrinol Metab 1999 84: 1172-1173. [Full Text]  

Wouter W. de Herder and Steven W.J. Lamberts
EDITORIAL: Tumor Localization—The Ectopic ACTH Syndrome
J Clin Endocrinol Metab 1999 84: 1184-1185. [Full Text]  

A. P. Heaney, N. Sharer, B. Rameh, J. M. Braganza, and P. N. Durrington
CLINICAL CASE SEMINAR: Prevention of Recurrent Pancreatitis in Familial Lipoprotein Lipase Deficiency with High-Dose Antioxidant Therapy
J Clin Endocrinol Metab 1999 84: 1203-1205. [Abstract] [Full Text]  

Robert Wozniak, Lee Beckwith, Howard Ratech, and Martin I. Surks
CLINICAL CASE SEMINAR: Maltoma of the Thyroid in a Man with Hashimoto’s Thyroiditis
J Clin Endocrinol Metab 1999 84: 1206-1209. [Abstract] [Full Text]  

Anna Nordenström, Claude Marcus, Magnus Axelson, Anna Wedell, and E. Martin Ritzén
CLINICAL CASE SEMINAR: Failure of Cortisone Acetate Treatment in Congenital Adrenal Hyperplasia because of Defective 11ß-Hydroxysteroid Dehydrogenase Reductase Activity
J Clin Endocrinol Metab 1999 84: 1210-1213. [Abstract] [Full Text]  

From the Clinical Research Centers:

Fred R. Sattler, S. Victoria Jaque, E. Todd Schroeder, Connie Olson, Michael P. Dube, Carmen Martinez, William Briggs, Richard Horton, and Stanley Azen
Effects of Pharmacological Doses of Nandrolone Decanoate and Progressive Resistance Training in Immunodeficient Patients Infected with Human Immunodeficiency Virus
J Clin Endocrinol Metab 1999 84: 1268-1276. [Abstract] [Full Text]  

Steven C. Elbein, Sandra J. Hasstedt, Kimberley Wegner, and Steven E. Kahn
Heritability of Pancreatic ß-Cell Function among Nondiabetic Members of Caucasian Familial Type 2 Diabetic Kindreds
J Clin Endocrinol Metab 1999 84: 1398-1403. [Abstract] [Full Text]  

Original Studies:

Michael B. Ranke, Anders Lindberg, Pierre Chatelain, Patrick Wilton, Wayne Cutfield, Kerstin Albertsson-Wikland, and David A. Price
Derivation and Validation of a Mathematical Model for Predicting the Response to Exogenous Recombinant Human Growth Hormone (GH) in Prepubertal Children with Idiopathic GH Deficiency
J Clin Endocrinol Metab 1999 84: 1174-1183. [Abstract] [Full Text]  

D. J. TORPY, C. C. CHEN, N. MULLEN, J. L. DOPPMAN, J. A. CARRASQUILLO, G. P. CHROUSOS, and L. K. NIEMAN
Lack of Utility of 111In-Pentetreotide Scintigraphy in Localizing Ectopic ACTH Producing Tumors: Follow-Up of 18 Patients
J Clin Endocrinol Metab 1999 84: 1186-1192. [Abstract] [Full Text]  

A. Tabarin, N. Valli, P. Chanson, Y. Bachelot, V. Rohmer, V. Bex-Bachellerie, B. Catargi, P. Roger, and F. Laurent
Usefulness of Somatostatin Receptor Scintigraphy in Patients with Occult Ectopic Adrenocorticotropin Syndrome
J Clin Endocrinol Metab 1999 84: 1193-1202. [Abstract] [Full Text]  

Joel S. Finkelstein and Amy L. Arnold
Increases in Bone Mineral Density after Discontinuation of Daily Human Parathyroid Hormone and Gonadotropin-Releasing Hormone Analog Administration in Women with Endometriosis
J Clin Endocrinol Metab 1999 84: 1214-1219. [Abstract] [Full Text]  

Richard C. Jenkins, A. Meguid El Nahas, Martin E. Wilkie, Colin B. Brown, Jenny Jones, Ezio Ghigo, and Richard J. M. Ross
The Effects of Dose, Nutrition, and Age on Hexarelin-Induced Anterior Pituitary Hormone Secretion in Adult Patients on Maintenance Hemodialysis
J Clin Endocrinol Metab 1999 84: 1220-1225. [Abstract] [Full Text]  

Yoshikatsu Nakai, Seiji Hamagaki, Ryuro Takagi, Ataru Taniguchi, and Fumihiko Kurimoto
Plasma Concentrations of Tumor Necrosis Factor-{alpha} (TNF-{alpha}) and Soluble TNF Receptors in Patients with Anorexia Nervosa
J Clin Endocrinol Metab 1999 84: 1226-1228. [Abstract] [Full Text]  

Osama Sabri, Michael Zimny, Gernot Schulz, Mathias Schreckenberger, Patrick Reinartz, Klaus Willmes, and Udalrich Buell
Success Rate of Radioiodine Therapy in Graves’ Disease: The Influence of Thyrostatic Medication
J Clin Endocrinol Metab 1999 84: 1229-1233. [Abstract] [Full Text]  

Roberto Lanzi, Marco Losa, Giovanna Mignogna, Andrea Caumo, and Antonio Ettore Pontiroli
The Control on Growth Hormone Release by Free Fatty Acids Is Maintained in Acromegaly
J Clin Endocrinol Metab 1999 84: 1234-1238. [Abstract] [Full Text]  

Heike E. Naserke, Ezio Bonifacio, and Anette-G. Ziegler
Immunoglobulin G Insulin Autoantibodies in BABYDIAB Offspring Appear Postnatally: Sensitive Early Detection Using a Protein A/G-Based Radiobinding Assay
J Clin Endocrinol Metab 1999 84: 1239-1243. [Abstract] [Full Text]  

Dorothee Büchter, Sigrid von Eckardstein, Arnold von Eckardstein, Axel Kamischke, Manuela Simoni, Hermann M. Behre, and Eberhard Nieschlag
Clinical Trial of Transdermal Testosterone and Oral Levonorgestrel for Male Contraception
J Clin Endocrinol Metab 1999 84: 1244-1249. [Abstract] [Full Text]  

P. Moghetti, R. Castello, N. Zamberlan, M. Rossini, D. Gatti, C. Negri, F. Tosi, M. Muggeo, and S. Adami
Spironolactone, But Not Flutamide, Administration Prevents Bone Loss in Hyperandrogenic Women Treated with Gonadotropin-Releasing Hormone Agonist
J Clin Endocrinol Metab 1999 84: 1250-1254. [Abstract] [Full Text]  

Kazuaki Gunji, Annamaria De Bellis, Sumihisa Kubota, Jil Swanson, Sylvia Wengrowicz, Bruce Cochran, Brian A. C. Ackrell, Mario Salvi, Antonio Bellastella, Antonio Bizzarro, Antonio A. Sinisi, and Jack R. Wall
Serum Antibodies against the Flavoprotein Subunit of Succinate Dehydrogenase Are Sensitive Markers of Eye Muscle Autoimmunity in Patients with Graves’ Hyperthyroidism
J Clin Endocrinol Metab 1999 84: 1255-1262. [Abstract] [Full Text]  

Daniel E. Flanagan, Julian C. Vaile, Graham W. Petley, Vivienne M. Moore, Ian F. Godsland, Richard A. Cockington, Jeffrey S. Robinson, and David I. Phillips
The Autonomic Control of Heart Rate and Insulin Resistance in Young Adults
J Clin Endocrinol Metab 1999 84: 1263-1267. [Abstract] [Full Text]  

Annamaria Colao, Gaetana Cerbone, Rosario Pivonello, Gianluca Aimaretti, Sandro Loche, Carolina Di Somma, Antongiulio Faggiano, Ginevra Corneli, Ezio Ghigo, and Gaetano Lombardi
The Growth Hormone (GH) Response to the Arginine Plus GH-Releasing Hormone Test Is Correlated to the Severity of Lipid Profile Abnormalities in Adult Patients with GH Deficiency
J Clin Endocrinol Metab 1999 84: 1277-1282. [Abstract] [Full Text]  

Huey Kiam How, Allen Yeoh, Thuan Chong Quah, Youngman Oh, Ron G. Rosenfeld, and Kok-Onn Lee
Insulin-Like Growth Factor Binding Proteins (IGFBPs) and IGFBP-Related Protein 1-Levels in Cerebrospinal Fluid of Children with Acute Lymphoblastic Leukemia
J Clin Endocrinol Metab 1999 84: 1283-1287. [Abstract] [Full Text]  

Matthew S. Gill, Andrew A. Toogood, Jenny Jones, Peter E. Clayton, and Stephen M. Shalet
Serum Leptin Response to the Acute and Chronic Administration of Growth Hormone (GH) to Elderly Subjects with GH Deficiency
J Clin Endocrinol Metab 1999 84: 1288-1295. [Abstract] [Full Text]  

M. Leonsson, J. Oscarsson, I. Bosaeus, B. K. Lundgren, G. Johannsson, O. Wiklund, and B. Å. Bengtsson
Growth Hormone (GH) Therapy in GH-Deficient Adults Influences the Response to a Dietary Load of Cholesterol and Saturated Fat in Terms of Cholesterol Synthesis, But Not Serum Low Density Lipoprotein Cholesterol Levels
J Clin Endocrinol Metab 1999 84: 1296-1303. [Abstract] [Full Text]  

S. Venturoli, O. Marescalchi, F. M. Colombo, S. Macrelli, B. Ravaioli, A. Bagnoli, R. Paradisi, and C. Flamigni
A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism
J Clin Endocrinol Metab 1999 84: 1304-1310. [Abstract] [Full Text]  

Greet Van den Berghe, Pieter Wouters, Frank Weekers, Subburaman Mohan, Robert C. Baxter, Johannes D. Veldhuis, Cyril Y. Bowers, and Roger Bouillon
Reactivation of Pituitary Hormone Release and Metabolic Improvement by Infusion of Growth Hormone-Releasing Peptide and Thyrotropin-Releasing Hormone in Patients with Protracted Critical Illness
J Clin Endocrinol Metab 1999 84: 1311-1323. [Abstract] [Full Text]  

Mohamad Maghnie, Carolina Strigazzi, Carmine Tinelli, Michele Autelli, Mariangela Cisternino, Sandro Loche, and Francesca Severi
Growth Hormone (GH) Deficiency (GHD) of Childhood Onset: Reassessment of GH Status and Evaluation of the Predictive Criteria for Permanent GHD in Young Adults
J Clin Endocrinol Metab 1999 84: 1324-1328. [Abstract] [Full Text]  

Françoise Borson-Chazot, André Serusclat, Yadh Kalfallah, Xavier Ducottet, Geneviève Sassolas, Sophie Bernard, Florence Labrousse, Jorge Pastene, Agnès Sassolas, Yves Roux, and François Berthezène
Decrease in Carotid Intima-Media Thickness after One Year Growth Hormone (GH) Treatment in Adults with GH Deficiency
J Clin Endocrinol Metab 1999 84: 1329-1333. [Abstract] [Full Text]  

Annewieke W. van den Beld, Ilpo T. Huhtaniemi, Kim S. L. Pettersson, Huibert A. P. Pols, Diederick E. Grobbee, Frank H. de Jong, and Steven W. J. Lamberts
Luteinizing Hormone and Different Genetic Variants, as Indicators of Frailty in Healthy Elderly Men
J Clin Endocrinol Metab 1999 84: 1334-1339. [Abstract] [Full Text]  

V. L. Green, V. Speirs, A. M. Landolt, P. M. Foy, and S. L. Atkin
17ß-Hydroxysteroid Dehydrogenase Type 1, 2, 3, and 4 Expression and Enzyme Activity in Human Anterior Pituitary Adenomas
J Clin Endocrinol Metab 1999 84: 1340-1345. [Abstract] [Full Text]  

René Klinkby Støving, Allan Flyvbjerg, Jan Frystyk, Sanne Fisker, Jørgen Hangaard, Michael Hansen-Nord, and Claus Hagen
Low Serum Levels of Free and Total Insulin-Like Growth Factor I (IGF-I) in Patients with Anorexia Nervosa Are Not Associated with Increased IGF-Binding Protein-3 Proteolysis
J Clin Endocrinol Metab 1999 84: 1346-1350. [Abstract] [Full Text]  

Cecilia Invitti, Francesca Pecori Giraldi, Antonella Dubini, Paola Moroni, Marco Losa, Roberta Piccoletti, and Francesco Cavagnini
Galanin Is Released by Adrenocorticotropin-Secreting Pituitary Adenomas in Vivo and in Vitro
J Clin Endocrinol Metab 1999 84: 1351-1356. [Abstract] [Full Text]  

Monique H. A. Kester, Ellen Kaptein, Thirza J. Roest, Caren H. van Dijk, Dick Tibboel, Walter Meinl, Hansruedi Glatt, Michael W. H. Coughtrie, and Theo J. Visser
Characterization of Human Iodothyronine Sulfotransferases
J Clin Endocrinol Metab 1999 84: 1357-1364. [Abstract] [Full Text]  

H. M. Fraser, N. P. Groome, and A. S. McNeilly
Follicle-Stimulating Hormone-Inhibin B Interactions during the Follicular Phase of the Primate Menstrual Cycle Revealed by Gonadotropin-Releasing Hormone Antagonist and Antiestrogen Treatment
J Clin Endocrinol Metab 1999 84: 1365-1369. [Abstract] [Full Text]  

Rosemary L. Balleine, Sybille M. N. Hunt, and Christine L. Clarke
Coexpression of Alternatively Spliced Estrogen and Progesterone Receptor Transcripts in Human Breast Cancer
J Clin Endocrinol Metab 1999 84: 1370-1377. [Abstract] [Full Text]  

Shoji Mihara, Noboru Suzuki, Sueshige Wakisaka, Satoshi Suzuki, Noriaki Sekita, Shoso Yamamoto, Nobuhiko Saito, Takashi Hoshino, and Tsuyoshi Sakane
Effects of Thyroid Hormones on Apoptotic Cell Death of Human Lymphocytes
J Clin Endocrinol Metab 1999 84: 1378-1385. [Abstract] [Full Text]  

Katleen Hostens, Zhidong Ling, Christiaan Van Schravendijk, and Daniel Pipeleers
Prolonged Exposure of Human ß-Cells to High Glucose Increases Their Release of Proinsulin during Acute Stimulation with Glucose or Arginine
J Clin Endocrinol Metab 1999 84: 1386-1390. [Abstract] [Full Text]  

Mi Hwa Lee, June Young Park, Bo Youn Cho, and Chi-Bom Chae
Expression of the Functional Extracellular Domain of Human Thyrotropin Receptor Using a Vaccinia Virus System: Its Purification and Analysis of Autoantibody Binding
J Clin Endocrinol Metab 1999 84: 1391-1397. [Abstract] [Full Text]  

Horst Donner, Ralf R. Tönjes, Bart Van der Auwera, Thorsten Siegmund, Jens Braun, Ilse Weets, Jürgen Herwig, Reinhard Kurth, Klaus Henning Usadel, and Klaus Badenhoop
The Presence or Absence of a Retroviral Long Terminal Repeat Influences the Genetic Risk for Type 1 Diabetes Conferred by Human Leukocyte Antigen DQ Haplotypes
J Clin Endocrinol Metab 1999 84: 1404-1408. [Abstract] [Full Text]  

C. Hansen, R. Rouhi, G. Förster, and G. J. Kahaly
Increased Sulfatation of Orbital Glycosaminoglycans in Graves’ Ophthalmopathy
J Clin Endocrinol Metab 1999 84: 1409-1413. [Abstract] [Full Text]  

Yoshio Nakamura, Takeshi Usui, Haruo Mizuta, Hiroyuki Murabe, Seiji Muro, Michio Suda, Kiyoshi Tanaka, Issei Tanaka, Akira Shimatsu, and Kazuwa Nakao
Characterization of Prophet of Pit-1 Gene Expression in Normal Pituitary and Pituitary Adenomas in Humans
J Clin Endocrinol Metab 1999 84: 1414-1419. [Abstract] [Full Text]  

Felice Petraglia, Pasquale Florio, Chiara Benedetto, Luca Marozio, Anna Maria Di Blasio, Carlo Ticconi, Emilio Piccione, Stefano Luisi, Andrea R. Genazzani, and Wyle Vale
Urocortin Stimulates Placental Adrenocorticotropin and Prostaglandin Release and Myometrial Contractility in Vitro
J Clin Endocrinol Metab 1999 84: 1420-1423. [Abstract] [Full Text]  

Juan Carlos Jaume, Jin Guo, David L. Pauls, Margita Zakarija, J. Maxwell McKenzie, Janice A. Egeland, C. Lynne Burek, Noel R. Rose, William H. Hoffman, Basil Rapoport, and Sandra M. McLachlan
Evidence for Genetic Transmission of Thyroid Peroxidase Autoantibody Epitopic "Fingerprints"
J Clin Endocrinol Metab 1999 84: 1424-1431. [Abstract] [Full Text]  

J. Nakamura, Q. Lu, G. Aberdeen, E. Albrecht, and A. Brodie
The Effect of Estrogen on Aromatase and Vascular Endothelial Growth Factor Messenger Ribonucleic Acid in the Normal Nonhuman Primate Mammary Gland
J Clin Endocrinol Metab 1999 84: 1432-1437. [Abstract] [Full Text]  

Akira Hishinuma, Junta Takamatsu, Yoshihide Ohyama, Tamotsu Yokozawa, Yumiko Kanno, Kanji Kuma, Shigeru Yoshida, Nobuo Matsuura, and Tamio Ieiri
Two Novel Cysteine Substitutions (C1263R and C1995S) of Thyroglobulin Cause a Defect in Intracellular Transport of Thyroglobulin in Patients with Congenital Goiter and the Variant Type of Adenomatous Goiter
J Clin Endocrinol Metab 1999 84: 1438-1444. [Abstract] [Full Text]  

T. Hahn, S. Barth, R. Graf, M. Engelmann, D. Beslagic, J. M. H. M. Reul, F. Holsboer, G. Dohr, and G. Desoye
Placental Glucose Transporter Expression Is Regulated by Glucocorticoids
J Clin Endocrinol Metab 1999 84: 1445-1452. [Abstract] [Full Text]  

Gen Hirasawa, Hironobu Sasano, Takashi Suzuki, Junji Takeyama, Yasunari Muramatu, Kouhei Fukushima, Nobuo Hiwatashi, Takayoshi Toyota, Hiroshi Nagura, and Zygmunt S. Krozowski
11ß-Hydroxysteroid Dehydrogenase Type 2 and Mineralocorticoid Receptor in Human Fetal Development
J Clin Endocrinol Metab 1999 84: 1453-1458. [Abstract] [Full Text]  

D. H. C. Khoo, J. Parma, C. Rajasoorya, S. C. Ho, and G. Vassart
A Germline Mutation of the Thyrotropin Receptor Gene Associated with Thyrotoxicosis and Mitral Valve Prolapse in a Chinese Family
J Clin Endocrinol Metab 1999 84: 1459-1462. [Abstract] [Full Text]  

Daniela Pasquali, Valentina Rossi, Domenico Prezioso, Vittorio Gentile, Vittorio Colantuoni, Tullio Lotti, Antonio Bellastella, and Antonio A. Sinisi
Changes in Tissue Transglutaminase Activity and Expression during Retinoic Acid-Induced Growth Arrest and Apoptosis in Primary Cultures of Human Epithelial Prostate Cells
J Clin Endocrinol Metab 1999 84: 1463-1469. [Abstract] [Full Text]  

M.-M. Huber-Buchholz, D. G. P. Carey, and R. J. Norman
COMMENTS: Restoration of Reproductive Potential by Lifestyle Modification in Obese Polycystic Ovary Syndrome: Role of Insulin Sensitivity and Luteinizing Hormone
J Clin Endocrinol Metab 1999 84: 1470-1474. [Abstract] [Full Text]  

Rapid Communications:

Vibeke Hatorp, Won-Chin Huang, and Poul Strange
Pharmacokinetic Profiles of Repaglinide in Elderly Subjects With Type 2 Diabetes
J Clin Endocrinol Metab 1999 84: 1475-1478. [Abstract] [Full Text]  

W. Yuan and L. C. Giudice
Insulin-Like Growth Factor-II Mediates The Steroidogenic and Growth Promoting Actions of Follicle Stimulating Hormone On Human Ovarian Pre-Antral Follicles Cultured In Vitro
J Clin Endocrinol Metab 1999 84: 1479-1482. [Abstract] [Full Text]  

A. Hinney, A. Schmidt, K. Nottebom, O. Heibült, I. Becker, A. Ziegler, G. Gerber, M. Sina, T. Görg, H. Mayer, W. Siegfried, M. Fichter, H. Remschmidt, and J. Hebebrand
Several Mutations in the Melanocortin-4 Receptor Gene Including a Nonsense and a Frameshift Mutation Associated with Dominantly Inherited Obesity in Humans
J Clin Endocrinol Metab 1999 84: 1483-1486. [Abstract] [Full Text]  

Letters to the Editor:

A. M. Parfitt and S. Adami
Comment on Calcium-Regulated Renal Calcium Handling in Healthy Men
J Clin Endocrinol Metab 1999 84: 1487. [Full Text]  

Ghada El-Hajj Fuleihan
Calcium-Regulated Renal Calcium Handling in Healthy Men—Authors’ Response
J Clin Endocrinol Metab 1999 84: 1487a-1488. [Full Text]  

Luisa Barzon, Francesco Fallo, and Nicoletta Sonino
Comment—Is There a Role for Low Doses of Mitotane (o,p'-DDD) as Adjuvant Therapy in Adrenocortical Carcinoma?
J Clin Endocrinol Metab 1999 84: 1488. [Full Text]  

Gabriel Dickstein
Is There a Role for Low Doses of Mitotane (o,p',DDD) as Adjuvant Therapy in Adrenocortical Carcinoma?—Authors’ Response
J Clin Endocrinol Metab 1999 84: 1488a-1489. [Full Text]  

Ernesto de Menis, Domenico Billeci, and Elisabetta Marton
Uneventful Pregnancy in an Acromegalic Patient Treated with Slow-Release Lanreotide: A Case Report
J Clin Endocrinol Metab 1999 84: 1489. [Full Text]  

A. Michael Parfitt
Comment on "True" and "Apparent" Bone Density Measurement In Children with GH Deficiency
J Clin Endocrinol Metab 1999 84: 1490. [Full Text]  

Giampiero I. Baroncelli, Silvano Bertelloni, Cinzia Ceccarelli, and Giuseppe Saggese
Measurement of Volumetric Bone Mineral Density Accurately Determines Degree of Lumbar Undermineralization in Children with Growth Hormone Deficiency—Author’s Response
J Clin Endocrinol Metab 1999 84: 1490a-1491. [Full Text]  

Francesco Cetta
Comment on Carney Complex and Related Syndromes and their Genetic Loci
J Clin Endocrinol Metab 1999 84: 1491. [Full Text]  

Constantine A. Stratakis
Carney Complex and Related Syndromes and their Genetic Loci—Author’s Response
J Clin Endocrinol Metab 1999 84: 1491a-1492. [Full Text]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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