JCEM -- Table of Contents (84 [1])

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Special Articles:

F-Xavier Pi-Sunyer and Blandine Laferrère: THERAPEUTIC CONTROVERSY: Metabolic Abnormalities and the Role of Leptin in Human Obesity
J Clin Endocrinol Metab 1999 84: 3-7. [Full Text]

Louis J. Aronne: THERAPEUTIC CONTROVERSY: Drug Therapy for Obesity—A Therapeutic Option?
J Clin Endocrinol Metab 1999 84: 7-10. [Full Text]

George A. Bray: THERAPEUTIC CONTROVERSY: Overweight Is Risking Fate
J Clin Endocrinol Metab 1999 84: 10-12. [Full Text]

J. E. Gunton, J. Stiel, R. J. Caterson, and A. McElduff: CLINICAL CASE SEMINAR: Anti-Thyroid Drugs and Antincutrophil Cytoplasmic Antibody Positive Vasculitis. A Case Report and Review of the Literature
J Clin Endocrinol Metab 1999 84: 13-16. [Full Text]

From the Clinical Research Centers:

Gary S. Wand, Deborah Mangold, and Mahmood Ali: Adrenocorticotropin Responses to Naloxone in Sons of Alcohol-Dependent Men
J Clin Endocrinol Metab 1999 84: 64-68. [Abstract] [Full Text]

Corrine K. Welt, Dennis J. McNicholl, Ann E. Taylor, and Janet E. Hall: Female Reproductive Aging Is Marked by Decreased Secretion of Dimeric Inhibin
J Clin Endocrinol Metab 1999 84: 105-111. [Abstract] [Full Text]

Mary Ann Banerji, Nuzhat Faridi, Rajesh Atluri, Rochelle L. Chaiken, and Harold E. Lebovitz: Body Composition, Visceral Fat, Leptin, and Insulin Resistance in Asian Indian Men
J Clin Endocrinol Metab 1999 84: 137-144. [Abstract] [Full Text]

Richard S. Legro, Allen R. Kunselman, William C. Dodson, and Andrea Dunaif: Prevalence and Predictors of Risk for Type 2 Diabetes Mellitus and Impaired Glucose Tolerance in Polycystic Ovary Syndrome: A Prospective, Controlled Study in 254 Affected Women
J Clin Endocrinol Metab 1999 84: 165-169. [Abstract] [Full Text]

Abhimanyu Garg, Ronald M. Peshock, and James L. Fleckenstein: Adipose Tissue Distribution Pattern in Patients with Familial Partial Lipodystrophy (Dunnigan Variety)
J Clin Endocrinol Metab 1999 84: 170-174. [Abstract] [Full Text]

K. M. Prestwood, D. L. Thompson, A. M. Kenny, M. J. Seibel, C. C. Pilbeam, and L. G. Raisz: Low Dose Estrogen and Calcium Have an Additive Effect on Bone Resorption in Older Women
J Clin Endocrinol Metab 1999 84: 179-183. [Abstract] [Full Text]

Alison M. Duncan, Barbara E. Merz, Xia Xu, Theodore C. Nagel, William R. Phipps, and Mindy S. Kurzer: Soy Isoflavones Exert Modest Hormonal Effects in Premenopausal Women
J Clin Endocrinol Metab 1999 84: 192-197. [Abstract] [Full Text]

Susan T. Haden, Edward M. Brown, Andrew L. Stoll, Jennifer Scott, and Ghada El-Hajj Fuleihan: The Effect of Lithium on Calcium-Induced Changes in Adrenocorticotrophin Levels
J Clin Endocrinol Metab 1999 84: 198-200. [Abstract] [Full Text]

Steven Grinspoon, Colleen Corcoran, Daniel Rosenthal, Takara Stanley, Kristin Parlman, Madeline Costello, Michael Treat, Sheila Davis, Belton Burrows, Nesli Basgoz, and Anne Klibanski: Quantitative Assessment of Cross-Sectional Muscle Area, Functional Status, and Muscle Strength in Men with the Acquired Immunodeficiency Syndrome Wasting Syndrome
J Clin Endocrinol Metab 1999 84: 201-206. [Abstract] [Full Text]

Original Studies:

Annamaria Colao, Alberto Cuocolo, Paolo Marzullo, Emanuele Nicolai, Diego Ferone, Luigia Florimonte, Marco Salvatore, and Gaetano Lombardi: Effects of 1-Year Treatment with Octreotide on Cardiac Performance in Patients with Acromegaly
J Clin Endocrinol Metab 1999 84: 17-23. [Abstract] [Full Text]

Laurence Leenhardt, Gilles Hejblum, Brigitte Franc, Laurence Du Pasquier Fediaevsky, Thierry Delbot, Danièle Le Guillouzic, Fabrice Ménégaux, Claudine Guillausseau, Catherine Hoang, Gérard Turpin, and André Aurengo: Indications and Limits of Ultrasound-Guided Cytology in the Management of Nonpalpable Thyroid Nodules
J Clin Endocrinol Metab 1999 84: 24-28. [Abstract] [Full Text]

Ryo Mitamura, Koichi Yano, Naoki Suzuki, Yoshiya Ito, Yoshio Makita, and Akimasa Okuno: Diurnal Rhythms of Luteinizing Hormone, Follicle-Stimulating Hormone, and Testosterone Secretion before the Onset of Male Puberty
J Clin Endocrinol Metab 1999 84: 29-37. [Abstract] [Full Text]

A. Govind, M. S. Obhrai, and R. N. Clayton: Polycystic Ovaries Are Inherited as an Autosomal Dominant Trait: Analysis of 29 Polycystic Ovary Syndrome and 10 Control Families
J Clin Endocrinol Metab 1999 84: 38-43. [Abstract] [Full Text]

Penelope P. Feuillan, Janet V. Jones, Kevin Barnes, Karen Oerter-Klein, and Gordon B. Cutler, Jr.: Reproductive Axis after Discontinuation of Gonadotropin-Releasing Hormone Analog Treatment of Girls with Precocious Puberty: Long Term Follow-Up Comparing Girls with Hypothalamic Hamartoma to Those with Idiopathic Precocious Puberty
J Clin Endocrinol Metab 1999 84: 44-49. [Abstract] [Full Text]

Arlan L. Rosenbloom, Antonio Selman Almonte, Milton R. Brown, Delbert A. Fisher, Lisa Baumbach, and John S. Parks: Clinical and Biochemical Phenotype of Familial Anterior Hypopituitarism from Mutation of the PROP1 Gene
J Clin Endocrinol Metab 1999 84: 50-57. [Abstract] [Full Text]

Omar Serri, Pascal St-Jacques, Maryam Sartippour, and Geneviève Renier: Alterations of Monocyte Function in Patients with Growth Hormone (GH) Deficiency: Effect of Substitutive GH Therapy
J Clin Endocrinol Metab 1999 84: 58-63. [Abstract] [Full Text]

Eric Baudin, Jean-Michel Bidart, Philippe Rougier, Vladimir Lazar, Pierre Ruffié, Jacques Ropers, Michel Ducreux, Frédéric Troalen, Jean-Christophe Sabourin, Etienne Comoy, Philippe Lasser, Thierry DeBaere, and Martin Schlumberger: Screening for Multiple Endocrine Neoplasia Type 1 and Hormonal Production in Apparently Sporadic Neuroendocrine Tumors
J Clin Endocrinol Metab 1999 84: 69-75. [Abstract] [Full Text]

Gianluca Gennarelli, Jan Holte, Mats Stridsberg, Ulrika Lundqvist, Marco Massobrio, Torbjörn Bäckström, and Christian Berne: Response of the Pituitary-Adrenal Axis to Hypoglycemic Stress in Women with the Polycystic Ovary Syndrome
J Clin Endocrinol Metab 1999 84: 76-81. [Abstract] [Full Text]

Nobuyasu Kawai, Susumu Kanzaki, Syouko Takano-Watou, Chiaki Tada, Yoshitaka Yamanaka, Tsuyoshi Miyata, Masanori Oka, and Yoshiki Seino: Serum Free Insulin-Like Growth Factor I (IGF-I), Total IGF-I, and IGF-Binding Protein-3 Concentrations in Normal Children and Children with Growth Hormone Deficiency
J Clin Endocrinol Metab 1999 84: 82-89. [Abstract] [Full Text]

Sabine Costagliola, Nils G. Morgenthaler, Rudolf Hoermann, Klaus Badenhoop, Joachim Struck, Dirk Freitag, Stefan Poertl, Wolfgang Weglöhner, Jörg M. Hollidt, Beate Quadbeck, Jacques E. Dumont, Petra-Maria Schumm-Draeger, Andreas Bergmann, Klaus Mann, Gilbert Vassart, and Klaus-Henning Usadel: Second Generation Assay for Thyrotropin Receptor Antibodies Has Superior Diagnostic Sensitivity for Graves’ Disease
J Clin Endocrinol Metab 1999 84: 90-97. [Abstract] [Full Text]

Mayumi Ishikawa, Susumu Yokoya, Katsuhiko Tachibana, Yukihiro Hasegawa, Toshiaki Yasuda, Etsurou Tokuhiro, Yoshihide Hashimoto, and Toshiaki Tanaka: Serum Levels of 20-Kilodalton Human Growth Hormone (GH) Are Parallel Those of 22-Kilodalton Human GH in Normal and Short Children
J Clin Endocrinol Metab 1999 84: 98-104. [Abstract] [Full Text]

Frederick C. W. Wu, Ram Balasubramanian, Titia M. T. Mulders, and Herjan J. T. Coelingh-Bennink: Oral Progestogen Combined with Testosterone as a Potential Male Contraceptive: Additive Effects between Desogestrel and Testosterone Enanthate in Suppression of Spermatogenesis, Pituitary-Testicular Axis, and Lipid Metabolism
J Clin Endocrinol Metab 1999 84: 112-122. [Abstract] [Full Text]

Thor Ueland, Jens Bollerslev, Tony Bill Hansen, Ebbe Nils Ebbesen, Lis Mosekilde, Kim Brixen, Allan Flyvbjerg, and Ole Djøseland: Increased Cortical Bone Content of Insulin-Like Growth Factors in Acromegalic Patients
J Clin Endocrinol Metab 1999 84: 123-127. [Abstract] [Full Text]

Naveed Sattar, Ian A. Greer, Peter J. Galloway, Chris J. Packard, James Shepherd, Theresa Kelly, and Alan Mathers: Lipid and Lipoprotein Concentrations in Pregnancies Complicated by Intrauterine Growth Restriction
J Clin Endocrinol Metab 1999 84: 128-130. [Abstract] [Full Text]

Andrew A. Toogood and Stephen M. Shalet: Growth Hormone Replacement Therapy in the Elderly with Hypothalamic-Pituitary Disease: A Dose-Finding Study
J Clin Endocrinol Metab 1999 84: 131-136. [Abstract] [Full Text]

Pål Aukrust, Charlotte J. Haug, Thor Ueland, Egil Lien, Fredrik Müller, Terje Espevik, Jens Bollerslev, and Stig S. Frøland: Decreased Bone Formative and Enhanced Resorptive Markers in Human Immunodeficiency Virus Infection: Indication of Normalization of the Bone-Remodeling Process during Highly Active Antiretroviral Therapy
J Clin Endocrinol Metab 1999 84: 145-150. [Abstract] [Full Text]

Leslie J. De Groot: Dangerous Dogmas in Medicine: The Nonthyroidal Illness Syndrome
J Clin Endocrinol Metab 1999 84: 151-164. [Full Text]

Ellen Werber Leschek, Janet Jones, Kevin M. Barnes, Suvimol C. Hill, and Gordon B. Cutler, Jr.: Six-Year Results of Spironolactone and Testolactone Treatment of Familial Male-Limited Precocious Puberty with Addition of Deslorelin after Central Puberty Onset
J Clin Endocrinol Metab 1999 84: 175-178. [Abstract] [Full Text]

N. Mekki, M. A. Christofilis, M. Charbonnier, C. Atlan-Gepner, C. Defoort, C. Juhel, P. Borel, H. Portugal, A. M. Pauli, B. Vialettes, and D. Lairon: Influence of Obesity and Body Fat Distribution on Postprandial Lipemia and Triglyceride-Rich Lipoproteins in Adult Women
J Clin Endocrinol Metab 1999 84: 184-191. [Abstract] [Full Text]

Jeffrey J. Zachwieja, Steven R. Smith, Jennifer C. Lovejoy, Jennifer C. Rood, Marlene M. Windhauser, and George A. Bray: Testosterone Administration Preserves Protein Balance But Not Muscle Strength during 28 Days of Bed Rest
J Clin Endocrinol Metab 1999 84: 207-212. [Abstract] [Full Text]

Peter Meidahl Petersen, Anna-Maria Andersson, Mikael Rørth, Gedske Daugaard, and Niels E. Skakkebæk: Undetectable Inhibin B Serum Levels in Men after Testicular Irradiation
J Clin Endocrinol Metab 1999 84: 213-215. [Abstract] [Full Text]

Christina Heppner, Martin Reincke, Sunita K. Agarwal, Patricia Mora, Bruno Allolio, A. Lee Burns, Allen M. Spiegel, and Stephen J. Marx: MEN1 Gene Analysis in Sporadic Adrenocortical Neoplasms
J Clin Endocrinol Metab 1999 84: 216-219. [Abstract] [Full Text]

Reinhard Feneberg, Monika Sparber, Johannes D. Veldhuis, Otto Mehls, Eberhard Ritz, and Franz Schaefer: Synchronous Fluctuations of Blood Insulin and Lactate Concentrations in Humans
J Clin Endocrinol Metab 1999 84: 220-227. [Abstract] [Full Text]

Michael W. Sullivan, Ann Stewart-Akers, Joel S. Krasnow, Sarah L. Berga, and Anthony J. Zeleznik: Ovarian Responses in Women to Recombinant Follicle-Stimulating Hormone and Luteinizing Hormone (LH): A Role for LH in the Final Stages of Follicular Maturation
J Clin Endocrinol Metab 1999 84: 228-232. [Abstract] [Full Text]

Jean-Claude Schaer and Jean Claude Reubi: High Gastrin and Cholecystokinin (CCK) Gene Expression in Human Neuronal, Renal, and Myogenic Stem Cell Tumors: Comparison with CCK-A and CCK-B Receptor Contents
J Clin Endocrinol Metab 1999 84: 233-239. [Abstract] [Full Text]

H. O. D. Critchley, R. L. Jones, R. G. Lea, T. A. Drudy, R. W. Kelly, A. R. W. Williams, and D. T. Baird: Role of Inflammatory Mediators in Human Endometrium during Progesterone Withdrawal and Early Pregnancy
J Clin Endocrinol Metab 1999 84: 240-248. [Abstract] [Full Text]

Monica R. Gadelha, Toni R. Prezant, Karina N. Une, Roberta P. Glick, Stanley F. Moskal, II, Mario Vaisman, Shlomo Melmed, Rhonda D. Kineman, and Lawrence A. Frohman: Loss of Heterozygosity on Chromosome 11q13 in Two Families with Acromegaly/Gigantism Is Independent of Mutations of the Multiple Endocrine Neoplasia Type I Gene
J Clin Endocrinol Metab 1999 84: 249-256. [Abstract] [Full Text]

Artur Mayerhofer, Hugh C. Hemmings, Jr., Gretchen L. Snyder, Paul Greengard, Sylvia Boddien, Ulrike Berg, and Cosima Brucker: Functional Dopamine-1 Receptors and DARPP-32 Are Expressed in Human Ovary and Granulosa Luteal Cells in Vitro
J Clin Endocrinol Metab 1999 84: 257-264. [Abstract] [Full Text]

Wanli Cheng, Ontario D. Lau, and Nada A. Abumrad: Two Antiatherogenic Effects of Progesterone on Human Macrophages; Inhibition of Cholesteryl Ester Synthesis and Block of Its Enhancement by Glucocorticoids
J Clin Endocrinol Metab 1999 84: 265-271. [Abstract] [Full Text]

Bernard Zinman, Anthony J. G. Hanley, Stewart B. Harris, Jeremy Kwan, and I. George Fantus: Circulating Tumor Necrosis Factor- ${alpha}$ Concentrations in a Native Canadian Population with High Rates of Type 2 Diabetes Mellitus
J Clin Endocrinol Metab 1999 84: 272-278. [Abstract] [Full Text]

Y. J. H. Janssen, J. Doornbos, and F. Roelfsema: Changes in Muscle Volume, Strength, and Bioenergetics during Recombinant Human Growth Hormone (GH) Therapy in Adults with GH Deficiency
J Clin Endocrinol Metab 1999 84: 279-284. [Abstract] [Full Text]

E. Ghigo, L. Gianotti, E. Arvat, J. Ramunni, M. R. Valetto, F. Broglio, M. Rolla, F. Cavagnini, and E. E. Müller: Effects of Recombinant Human Insulin-Like Growth Factor I Administration on Growth Hormone (GH) Secretion, Both Spontaneous and Stimulated by GH-Releasing Hormone or Hexarelin, a Peptidyl GH Secretagogue, in Humans
J Clin Endocrinol Metab 1999 84: 285-290. [Abstract] [Full Text]

Falguni A. Patel, Vicki L. Clifton, K. Chwalisz, and John R. G. Challis: Steroid Regulation of Prostaglandin Dehydrogenase Activity and Expression in Human Term Placenta and Chorio-Decidua in Relation to Labor
J Clin Endocrinol Metab 1999 84: 291-299. [Abstract] [Full Text]

K. Lewandowski, R. Horn, C. J. O’Callaghan, D. Dunlop, G. F. Medley, P. O’Hare, and G. Brabant: Free Leptin, Bound Leptin, and Soluble Leptin Receptor in Normal and Diabetic Pregnancies
J Clin Endocrinol Metab 1999 84: 300-306. [Abstract] [Full Text]

E. R. Christ, M. H. Cummings, E. Albany, A. M. Umpleby, P. J. Lumb, A. S. Wierzbicki, R. P. Naoumova, M. A. Boroujerdi, P. H. Sönksen, and D. L. Russell-Jones: Effects of Growth Hormone (GH) Replacement Therapy on Very Low Density Lipoprotein Apolipoprotein B100 Kinetics in Patients with Adult GH Deficiency: A Stable Isotope Study
J Clin Endocrinol Metab 1999 84: 307-316. [Abstract] [Full Text]

Toshio Tsushima, Yuzuru Katoh, Yukitaka Miyachi, Kazuo Chihara, Akira Teramoto, Minoru Irie, and Yoshihide Hashimoto: Serum Concentration of 20K Human Growth Hormone (20K hGH) Measured by a Specific Enzyme-Linked Immunosorbent Assay
J Clin Endocrinol Metab 1999 84: 317-322. [Abstract] [Full Text]

Rong-Yu Liu, Jiang-Ning Zhou, Joop van Heerikhuize, Michel A. Hofman, and Dick F. Swaab: Decreased Melatonin Levels in Postmortem Cerebrospinal Fluid in Relation to Aging, Alzheimer’s Disease, and Apolipoprotein E- ${epsilon}$ 4/4 Genotype
J Clin Endocrinol Metab 1999 84: 323-327. [Abstract] [Full Text]

Liping Yu, Karl W. Brewer, Sherman Gates, Anya Wu, Tianbao Wang, Sunanda R. Babu, Peter A. Gottlieb, Brian M. Freed, Janelle Noble, Henry A. Erlich, Marian J. Rewers, and George S. Eisenbarth: DRB104 and DQ Alleles: Expression of 21-Hydroxylase Autoantibodies and Risk of Progression to Addison’s Disease
J Clin Endocrinol Metab 1999 84: 328-335. [Abstract] [Full Text]

P. Kopp, O. Karamanoglu Arseven, L. Sabacan, T. Kotlar, J. Dupuis, H. Cavaliere, C. L. S. Santos, J. L. Jameson, and G. Medeiros-Neto: Phenocopies for Deafness and Goiter Development in a Large Inbred Brazilian Kindred with Pendred’s Syndrome Associated with a Novel Mutation in the PDS Gene
J Clin Endocrinol Metab 1999 84: 336-341. [Abstract] [Full Text]

Diane M. Duffy, Dennis R. Stewart, and Richard L. Stouffer: Titrating Luteinizing Hormone Replacement to Sustain the Structure and Function of the Corpus Luteum after Gonadotropin-Releasing Hormone Antagonist Treatment in Rhesus Monkeys
J Clin Endocrinol Metab 1999 84: 342-349. [Abstract] [Full Text]

Carlos A. Suárez-Quian, Francisco Martínez-García, Manuel Nistal, and Javier Regadera: Androgen Receptor Distribution in Adult Human Testis
J Clin Endocrinol Metab 1999 84: 350-358. [Abstract] [Full Text]

Jiro Fujimoto, Hideki Sakaguchi, Reiko Hirose, and Teruhiko Tamaya: Expression of Platelet-Derived Endothelial Cell Growth Factor (PD-ECGF) Related to Angiogenesis in Ovarian Endometriosis
J Clin Endocrinol Metab 1999 84: 359-362. [Abstract] [Full Text]

Ryo Okazaki, Noriko Chikatsu, Masami Nakatsu, Yasuhiro Takeuchi, Miho Ajima, Junko Miki, Toshiro Fujita, Masanobu Arai, Yasuo Totsuka, Koshi Tanaka, and Seiji Fukumoto: A Novel Activating Mutation in Calcium-Sensing Receptor Gene Associated with a Family of Autosomal Dominant Hypocalcemia
J Clin Endocrinol Metab 1999 84: 363-366. [Abstract] [Full Text]

Ann M. Møller, Louise T. Dalgaard, Louise Ambye, Lars Hansen, Ole Schmitz, Torben Hansen, and Oluf Pedersen: COMMENTS: A Novel Phe75fsdelT Mutation in the Hepatocyte Nuclear Factor-4 ${alpha}$ Gene in a Danish Pedigree with Maturity-Onset Diabetes of the Young
J Clin Endocrinol Metab 1999 84: 367-369. [Abstract] [Full Text]

Rapid Communications:

L. Ola Nilsson, Anders Boman, Lars Sävendahl, Giedre Grigelioniene, Claes Ohlsson, E. Martin Ritzén, and Joanna Wroblewski: Demonstration of Estrogen Receptor-ß Immunoreactivity in Human Growth Plate Cartilage
J Clin Endocrinol Metab 1999 84: 370-373. [Abstract] [Full Text]

C. Evans, N. G. Morgenthaler, S. Lee, D. H. Llewellyn, R. Clifton-Bligh, R. John, J. H. Lazarus, V. K. K. Chatterjee, and M. Ludgate: Development of a Luminescent Bioassay for Thyroid Stimulating Antibodies
J Clin Endocrinol Metab 1999 84: 374-377. [Abstract] [Full Text]

S. Nimkarn, B. I. Cerame, J.-Q. Wei, M. Dumic, L. Brkljacic, M. I. New, and R. C. Wilson: Congenital Adrenal Hyperplasia (21-Hydroxylase Deficiency) Without Demonstrable Genetic Mutations
J Clin Endocrinol Metab 1999 84: 378-381. [Abstract] [Full Text]

Letters to the Editor:

Philippe L. Selvais and Dominique M. Maiter: Further Arguments for a Functional Difference Between Pituitary Corticotroph Macroadenomas and Microadenomas
J Clin Endocrinol Metab 1999 84: 382. [Full Text]

Laurence Katznelson and Anne Klibanski: Biochemical Assessment in Patients with Cushing’s Disease due to Corticotroph Macroadenomas—Authors’ Response
J Clin Endocrinol Metab 1999 84: 382a-383. [Full Text]

Shoichiro Nagasaka, San-e Ishikawa, and Toshikazu Saito: Comment on Glucose-To-Insulin Ratio as a Measure of Insulin Sensitivity in Women with PCOS
J Clin Endocrinol Metab 1999 84: 383. [Full Text]

Richard S. Legro and Andrea Dunaif: Fasting Glucose to Insulin Ratio, or Product of Glucose and Insulin?—Authors’ Response
J Clin Endocrinol Metab 1999 84: 383a. [Full Text]

Arthur S. Leon: Comment on Effect of Large Doses of Aspartame on Urinary Calcium Excretion
J Clin Endocrinol Metab 1999 84: 383b-384. [Full Text]

UN Nguyen: Increased Urinary Calcium Excretion after Acute Aspartame Ingestion in Healthy Subjects—Authors’ Response
J Clin Endocrinol Metab 1999 84: 384. [Full Text]

Joseph L. Shaker, Brian P. Moore, and Michael P. Whyte: Hyperparathyroidism and Increased Serum IGF-Binding Protein-2 Levels in Hepatitis C-Associated Osteosclerosis
J Clin Endocrinol Metab 1999 84: 384a-385. [Full Text]