Articles listed in blue may be of special interest to clinicians.

Special Articles:

Lorraine A. Fitzpatrick and M. D.

EDITORIAL: Coronary Artery Disease in Women—an Equal Opportunity Killer
J Clin Endocrinol Metab 1998 83: 719-720. [Full Text]  

Vivien Herman-Bonert, Maria Seliverstov, and Shlomo Melmed

CLINICAL CASE SEMINAR: Pregnancy in Acromegaly: Successful Therapeutic Outcome
J Clin Endocrinol Metab 1998 83: 727-731. [Full Text]  

From the Clinical Research Centers:

Felicia Cosman, Jeri Nieves, Lillian Woelfert, Susan Gordon, Victor Shen, and Robert Lindsay

Parathyroid Responsivity in Postmenopausal Women with Osteoporosis During Treatment with Parathyroid Hormone
J Clin Endocrinol Metab 1998 83: 788-790. [Abstract] [Full Text]  

Anne B. Namnoum, George R. Merriam, Arnold M. Moses, and Michael A. Levine

Reproductive Dysfunction in Women with Albright’s Hereditary Osteodystrophy
J Clin Endocrinol Metab 1998 83: 824-829. [Abstract] [Full Text]  

Christina Wang, Nancy G. Berman, Johannes D. Veldhuis, Tina Der, Veronica McDonald, Barbara Steiner, and Ronald S. Swerdloff

Graded Testosterone Infusions Distinguish Gonadotropin Negative-Feedback Responsiveness in Asian and White Men—A Clinical Research Center Study
J Clin Endocrinol Metab 1998 83: 870-876. [Abstract] [Full Text]  

Original Studies:

Thomas B. Clarkson, Mary S. Anthony, and Christopher P. Jerome

Lack of Effect of Raloxifene on Coronary Artery Atherosclerosis of Postmenopausal Monkeys
J Clin Endocrinol Metab 1998 83: 721-726. [Abstract] [Full Text]  

Carolina A. Moreira Kulak, Cristina Bandeira, Dora Voss, Sylwester M. Sobieszczyk, Shonni J. Silverberg, Francisco Bandeira, and John P. Bilezikian

Marked Improvement in Bone Mass after Parathyroidectomy in Osteitis Fibrosa Cystica
J Clin Endocrinol Metab 1998 83: 732-735. [Full Text]  

J. Hangaard, M. Andersen, E. Grodum, O. Koldkjær, and C. Hagen

Pulsatile Luteinizing Hormone Secretion in Patients with Addison’s Disease. Impact of Glucocorticoid Substitution
J Clin Endocrinol Metab 1998 83: 736-743. [Abstract] [Full Text]  

Roman Hovorka, Ludovic Chassin, Stephen D. Luzio, Rebecca Playle, and David R. Owens

Pancreatic ß-Cell Responsiveness during Meal Tolerance Test: Model Assessment in Normal Subjects and Subjects with Newly Diagnosed Noninsulin-Dependent Diabetes Mellitus
J Clin Endocrinol Metab 1998 83: 744-750. [Abstract] [Full Text]  

Hassan M. Heshmati, B. Lawrence Riggs, Mary F. Burritt, Carol A. McAlister, Peter C. Wollan, and Sundeep Khosla

Effects of the Circadian Variation in Serum Cortisol on Markers of Bone Turnover and Calcium Homeostasis in Normal Postmenopausal Women
J Clin Endocrinol Metab 1998 83: 751-756. [Abstract] [Full Text]  

D. I. W. Phillips, D. J. P. Barker, C. H. D. Fall, J. R. Seckl, C. B. Whorwood, P. J. Wood, and B. R. Walker

Elevated Plasma Cortisol Concentrations: A Link between Low Birth Weight and the Insulin Resistance Syndrome?
J Clin Endocrinol Metab 1998 83: 757-760. [Abstract] [Full Text]  

Laurence Katznelson, Peter N. Riskind, Velia C. Saxe, and Anne Klibanski

Prolactin Pulsatile Characteristics in Postmenopausal Women
J Clin Endocrinol Metab 1998 83: 761-764. [Abstract] [Full Text]  

Peter Laurberg, Klaus M. Pedersen, Astradur Hreidarsson, Nikulas Sigfusson, Eigil Iversen, and Preben R. Knudsen

Iodine Intake and the Pattern of Thyroid Disorders: A Comparative Epidemiological Study of Thyroid Abnormalities in the Elderly in Iceland and in Jutland, Denmark
J Clin Endocrinol Metab 1998 83: 765-769. [Abstract] [Full Text]  

Ilona Berndt, Marlene Reuter, B. Saller, Karin Frank-Raue, P. Groth, M. Grußendorf, F. Raue, M. M. Ritter, and W. Höppner

A New Hot Spot for Mutations in the ret Protooncogene Causing Familial Medullary Thyroid Carcinoma and Multiple Endocrine Neoplasia Type 2A
J Clin Endocrinol Metab 1998 83: 770-774. [Abstract] [Full Text]  

Annamaria Colao, Paolo Marzullo, Diego Ferone, Stefano Spiezia, Gaetana Cerbone, Valeria Marinò, Antonella Di Sarno, Bartolomeo Merola, and Gaetano Lombardi

Prostatic Hyperplasia: An Unknown Feature of Acromegaly
J Clin Endocrinol Metab 1998 83: 775-779. [Abstract] [Full Text]  

E. Papini, L. Petrucci, R. Guglielmi, C. Panunzi, R. Rinaldi, V. Bacci, A. Crescenzi, F. Nardi, R. Fabbrini, and C. M. Pacella

Long-Term Changes in Nodular Goiter: A 5-Year Prospective Randomized Trial of Levothyroxine Suppressive Therapy for Benign Cold Thyroid Nodules
J Clin Endocrinol Metab 1998 83: 780-783. [Abstract] [Full Text]  

Elizabeth A. Cummings, Sonia R. Salisbury, Morris L. Givner, and Roger S. Rittmaster

Testolactone-Associated High Androgen Levels, a Pharmacologic Effect or a Laboratory Artifact?
J Clin Endocrinol Metab 1998 83: 784-787. [Abstract] [Full Text]  

Elke D. Eckert, Claire Pomeroy, Nancy Raymond, Peter F. Kohler, Paul Thuras, and Cyril Y. Bowers

Leptin in Anorexia Nervosa
J Clin Endocrinol Metab 1998 83: 791-795. [Abstract] [Full Text]  

Daniel Flanagan, Peter Wood, Robert Sherwin, Kwasi Debrah, and David Kerr

Gin and Tonic and Reactive Hypoglycemia: What Is Important–the Gin, the Tonic, or Both?
J Clin Endocrinol Metab 1998 83: 796-800. [Abstract] [Full Text]  

Georgina Pearce, D. Aaron Tabensky, Pierre D. Delmas, H. W. Gordon Baker, and Ego Seeman

Corticosteroid-Induced Bone Loss in Men
J Clin Endocrinol Metab 1998 83: 801-806. [Abstract] [Full Text]  

Carolina Di Somma, Annamaria Colao, Antonella Di Sarno, Michele Klain, Maria Luisa Landi, Giuseppina Facciolli, Rosario Pivonello, Nicola Panza, Marco Salvatore, and Gaetano Lombardi

Bone Marker and Bone Density Responses to Dopamine Agonist Therapy in Hyperprolactinemic Males
J Clin Endocrinol Metab 1998 83: 807-813. [Abstract] [Full Text]  

Roger S. Rittmaster, E. Carl Abbott, Robert Douglas, Morris L. Givner, Lea Lehmann, Sethu Reddy, Sonia R. Salisbury, Allan H. Shlossberg, Meng H. Tan, and Samuel E. York

Effect of Methimazole, with or without L-Thyroxine, on Remission Rates in Graves’ Disease
J Clin Endocrinol Metab 1998 83: 814-818. [Abstract] [Full Text]  

Ronald L. Prigeon, Steven E. Kahn, and Daniel Porte, Jr.

Effect of Troglitazone on B Cell Function, Insulin Sensitivity, and Glycemic Control in Subjects with Type 2 Diabetes Mellitus
J Clin Endocrinol Metab 1998 83: 819-823. [Abstract] [Full Text]  

Finn Noe Bennedbæk, Lars Kjær Nielsen, and Laszlo Hegedüs

Effect of Percutaneous Ethanol Injection Therapy Versus Suppressive Doses of L-Thyroxine on Benign Solitary Solid Cold Thyroid Nodules: A Randomized Trial
J Clin Endocrinol Metab 1998 83: 830-835. [Abstract] [Full Text]  

Gretchen P. Eberhart, Armando J. Mendez, and Mason W. Freeman

Decreased Cholesterol Efflux from Fibroblasts of a Patient without Tangier Disease, but with Markedly Reduced High Density Lipoprotein Cholesterol Levels
J Clin Endocrinol Metab 1998 83: 836-846. [Abstract] [Full Text]  

Susan K. Fried, Dove A. Bunkin, and Andrew S. Greenberg

Omental and Subcutaneous Adipose Tissues of Obese Subjects Release Interleukin-6: Depot Difference and Regulation by Glucocorticoid
J Clin Endocrinol Metab 1998 83: 847-850. [Abstract] [Full Text]  

Daniel S. McConnell, QiFa Wang, Patrick M. Sluss, Nicola Bolf, Rita H. Khoury, Alan L. Schneyer, A. Rees Midgley, Jr., Nancy E. Reame, William F. Crowley, Jr., and Vasantha Padmanabhan

A Two-Site Chemiluminescent Assay for Activin-Free Follistatin Reveals That Most Follistatin Circulating in Men and Normal Cycling Women Is in an Activin-Bound State
J Clin Endocrinol Metab 1998 83: 851-858. [Abstract] [Full Text]  

Akira Katsuki, Yasuhiro Sumida, Shuichi Murashima, Kazuya Murata, Yoshihiro Takarada, Kuninobu Ito, Masashi Fujii, Ken Tsuchihashi, Hiroyuki Goto, Kaname Nakatani, and Yutaka Yano

Serum Levels of Tumor Necrosis Factor- Are Increased in Obese Patients with Noninsulin-Dependent Diabetes Mellitus
J Clin Endocrinol Metab 1998 83: 859-862. [Abstract] [Full Text]  

A. M. Parfitt, Q. Wang, and S. Palnitkar

Rates of Cell Proliferation in Adenomatous, Suppressed, and Normal Parathyroid Tissue: Implications for Pathogenesis
J Clin Endocrinol Metab 1998 83: 863-869. [Abstract] [Full Text]  

Michaela Luconi, Lorella Bonaccorsi, Mario Maggi, Paola Pecchioli, Csilla Krausz, Gianni Forti, and Elisabetta Baldi

Identification and Characterization of Functional Nongenomic Progesterone Receptors on Human Sperm Membrane
J Clin Endocrinol Metab 1998 83: 877-885. [Abstract] [Full Text]  

Heike Hellmold, Tove Rylander, Malin Magnusson, Eva Reihnér, Margaret Warner, and Jan-Åke Gustafsson

Characterization of Cytochrome P450 Enzymes in Human Breast Tissue from Reduction Mammaplasties
J Clin Endocrinol Metab 1998 83: 886-895. [Abstract] [Full Text]  

Janice D. Wagner, Michael J. Thomas, J. Koudy Williams, Li Zhang, Kathryn A. Greaves, and William T. Cefalu

Insulin Sensitivity and Cardiovascular Risk Factors in Ovariectomized Monkeys with Estradiol Alone or Combined with Nomegestrol Acetate
J Clin Endocrinol Metab 1998 83: 896-901. [Abstract] [Full Text]  

C. M. Halleux, I. Servais, B. A. Reul, R. Detry, and S. M. Brichard

Multihormonal Control of ob Gene Expression and Leptin Secretion from Cultured Human Visceral Adipose Tissue: Increased Responsiveness to Glucocorticoids in Obesity
J Clin Endocrinol Metab 1998 83: 902-910. [Abstract] [Full Text]  

D. Mazzeo, P. Viganó, A. M. Di Blasio, F. Sinigaglia, M. Vignali, and P. Panina-Bordignon

Interleukin-12 and Its Free p40 Subunit Regulate Immune Recognition of Endometrial Cells: Potential Role in Endometriosis
J Clin Endocrinol Metab 1998 83: 911-916. [Abstract] [Full Text]  

Nannette A. T. M. Huizenga, Pieter de Lange, Jan W. Koper, Richard N. Clayton, William E. Farrell, Aart Jan van der Lely, Albert O. Brinkmann, Frank H. de Jong, and Steven W. J. Lamberts

Human Adrenocorticotropin-Secreting Pituitary Adenomas Show Frequent Loss of Heterozygosity at the Glucocorticoid Receptor Gene Locus
J Clin Endocrinol Metab 1998 83: 917-921. [Abstract] [Full Text]  

A. M. Wilson, L. C. McFarlane, and B. J. Lipworth

Effects of Low and High Doses of Inhaled Flunisolide and Triamcinolone Acetonide on Basal and Dynamic Measures of Adrenocortical Activity in Healthy Volunteers
J Clin Endocrinol Metab 1998 83: 922-925. [Abstract] [Full Text]  

Graciela Krikun, Frederick Schatz, Nigel Mackman, Seth Guller, and Charles J. Lockwood

Transcriptional Regulation of the Tissue Factor Gene by Progestins in Human Endometrial Stromal Cells
J Clin Endocrinol Metab 1998 83: 926-930. [Abstract] [Full Text]  

Niels Moller, Peter O’Brien, and K. Sreekumaran Nair

Disruption of the Relationship between Fat Content and Leptin Levels with Aging in Humans
J Clin Endocrinol Metab 1998 83: 931-934. [Abstract] [Full Text]  

J. A. Fischer, F. Egert, E. Werder, and W. Born

An Inherited Mutation Associated with Functional Deficiency of the -Subunit of the Guanine Nucleotide-Binding Protein G_s in Pseudo- and Pseudopseudohypoparathyroidism
J Clin Endocrinol Metab 1998 83: 935-938. [Abstract] [Full Text]  

Luigi Gennari, Lucia Becherini, Laura Masi, Riccardo Mansani, Stefano Gonnelli, Chiara Cepollaro, Sandra Martini, Andrea Montagnani, Giuseppe Lentini, Angela Maria Becorpi, and Maria Luisa Brandi

Vitamin D and Estrogen Receptor Allelic Variants in Italian Postmenopausal Women: Evidence of Multiple Gene Contribution to Bone Mineral Density
J Clin Endocrinol Metab 1998 83: 939-944. [Abstract] [Full Text]  

Mikael Nilsson, Johanna Husmark, Ulla Björkman, and Lars E. Ericson

Cytokines and Thyroid Epithelial Integrity: Interleukin-1 Induces Dissociation of the Junctional Complex and Paracellular Leakage in Filter-Cultured Human Thyrocytes
J Clin Endocrinol Metab 1998 83: 945-952. [Abstract] [Full Text]  

Jan S. Krüssel, Hong-Yuan Huang, Carlos Simón, Barry Behr, Andrea R. Pape, Yan Wen, Peter Bielfeld, and Mary Lake Polan

Single Blastomeres within Human Preimplantation Embryos Express Different Amounts of Messenger Ribonucleic Acid for ß-Actin and Interleukin-1 Receptor Type I
J Clin Endocrinol Metab 1998 83: 953-959. [Abstract] [Full Text]  

Chisato Tanaka, Katsuhiko Yoshimoto, Shozo Yamada, Hiroshi Nishioka, Setsuko Ii, Maki Moritani, Takashi Yamaoka, and Mitsuo Itakura

Absence of Germ-Line Mutations of the Multiple Endocrine Neoplasia Type 1 (MEN1) Gene in Familial Pituitary Adenoma in Contrast to MEN1 in Japanese
J Clin Endocrinol Metab 1998 83: 960-965. [Abstract] [Full Text]  

Michelle B. Sholar, Jack H. Mendelson, Nancy K. Mello, Arthur J. Siegel, Marc J. Kaufman, Jonathan M. Levin, Perry F. Renshaw, and Bruce M. Cohen

Concurrent Pharmacokinetic Analysis of Plasma Cocaine and Adrenocorticotropic Hormone in Men
J Clin Endocrinol Metab 1998 83: 966-968. [Abstract] [Full Text]  

Sally L. Mellor, Michelle G. Richards, John S. Pedersen, David M. Robertson, and Gail P. Risbridger

Loss of the Expression and Localization of Inhibin -Subunit in High Grade Prostate Cancer
J Clin Endocrinol Metab 1998 83: 969-975. [Abstract] [Full Text]  

Graham W. Aberdeen, Maria G. Leavitt, Gerald J. Pepe, and Eugene D. Albrecht

Effect of Maternal Betamethasone Administration at Midgestation on Baboon Fetal Adrenal Gland Development and Adrenocorticotropin Receptor Messenger Ribonucleic Acid Expression
J Clin Endocrinol Metab 1998 83: 976-982. [Abstract] [Full Text]  

Salman Azhar, Louisa Tsai, Satyanarayana Medicherla, Yasmine Chandrasekher, Linda Giudice, and Eve Reaven

Human Granulosa Cells Use High Density Lipoprotein Cholesterol for Steroidogenesis
J Clin Endocrinol Metab 1998 83: 983-991. [Abstract] [Full Text]  

Masashi Hirai, Susumu Suzuki, Masatoshi Onoda, Yoshinori Hinokio, Aki Hirai, Masataka Ohtomo, Masaki Chiba, Shigeru Kasuga, Satoshi Hirai, Yoshinori Satoh, Hiroaki Akai, Shigeaki Miyabayashi, and Takayoshi Toyota

Mitochondrial Deoxyribonucleic Acid 3256C-T Mutation in a Japanese Family with Noninsulin-Dependent Diabetes Mellitus
J Clin Endocrinol Metab 1998 83: 992-994. [Abstract] [Full Text]  

B. Calvo, J. R. Bilbao, I. Urrutia, J. Eizaguirre, S. Gaztambide, and L. Castaño

Identification of a Novel Nonsense Mutation and a Missense Substitution in the Vasopressin-Neurophysin II Gene in Two Spanish Kindreds with Familial Neurohypophyseal Diabetes Insipidus
J Clin Endocrinol Metab 1998 83: 995-997. [Abstract] [Full Text]  

R. S. Bahn, C. M. Dutton, N. Natt, W. Joba, C. Spitzweg, and A. E. Heufelder

Thyrotropin Receptor Expression in Graves’ Orbital Adipose/Connective Tissues: Potential Autoantigen in Graves’ Ophthalmopathy
J Clin Endocrinol Metab 1998 83: 998-1002. [Abstract] [Full Text]  

Francesco Cetta, Gennaro Chiappetta, Rosa Marina Melillo, Margherita Petracci, Giulia Montalto, Massimo Santoro, and Alfredo Fusco

The ret/ptc1 Oncogene Is Activated in Familial Adenomatous Polyposis-Associated Thyroid Papillary Carcinomas
J Clin Endocrinol Metab 1998 83: 1003-1006. [Abstract] [Full Text]  

J. Rendl, D. Bier, T. Groh, and C. Reiners

Rapid Urinary Iodide Test
J Clin Endocrinol Metab 1998 83: 1007-1012. [Abstract] [Full Text]  

D. J. Kennaway and A. Voultsios

COMMENTS: Circadian Rhythm of Free Melatonin in Human Plasma
J Clin Endocrinol Metab 1998 83: 1013-1015. [Abstract] [Full Text]  

Issei Yoshiuchi, Ryosuke Shingu, Hiromu Nakajima, Tomoya Hamaguchi, Yukio Horikawa, Tomoyuki Yamasaki, Takanori Oue, Akira Ono, Jun-ichiro Miyagawa, Mitsuyoshi Namba, Toshiaki Hanafusa, and Yuji Matsuzawa

COMMENTS: Mutation/Polymorphism Scanning of Glucose-6-Phosphatase Gene Promoter in Noninsulin-Dependent Diabetes Mellitus Patients
J Clin Endocrinol Metab 1998 83: 1016-1019. [Abstract] [Full Text]  

Andrzej Slominski, Gennady Ermak, Joseph E. Mazurkiewicz, James Baker, and Jacobo Wortsman

COMMENTS: Characterization of Corticotropin-Releasing Hormone (CRH) in Human Skin
J Clin Endocrinol Metab 1998 83: 1020-1024. [Abstract] [Full Text]  

Rapid Communications:

Alfred W. Brandenberger, Meng Kian Tee, and Roberts B. Jaffe

Estrogen Receptor Alpha (ER-) and Beta (ER-ß) mRNAs in Normal Ovary, Ovarian Serous Cystadenocarcinoma and Ovarian Cancer Cell Lines: Down-Regulation of ER-ß in Neoplastic Tissues
J Clin Endocrinol Metab 1998 83: 1025-1028. [Abstract] [Full Text]  

Felice Petraglia, Stefano Luisi, Patricia Pautier, Jean-Christophe Sabourin, Rodolfo Rey, Catherine Lhomme, and Jean-Michel Bidart

Inhibin B Is the Major Form of Inhibin/Activin Family Secreted by Granulosa Cell Tumors
J Clin Endocrinol Metab 1998 83: 1029-1032. [Abstract] [Full Text]  

Susan E. Taymans, Svetlana Pack, Evgenia Pak, David J. Torpy, Zhengping Zhuang, and Constantine A. Stratakis

Human CYP11B2 (Aldosterone Synthase) Maps To Chromosome 8q24.3
J Clin Endocrinol Metab 1998 83: 1033-1036. [Abstract] [Full Text]  

Bernd Jilma, Petra Stohlawetz, Thomas Pernerstorfer, Hans-Georg Eichler, Claudia Müllner, and Stylianos Kapiotis

Glucocorticoids Dose-Dependently Increase Plasma Levels of Granulocyte Colony Stimulating Factor in Man
J Clin Endocrinol Metab 1998 83: 1037-1040. [Abstract] [Full Text]  

Letters to the Editor:

Jun Minamikawa, Mika Yamauchi, Daisuke Inoue, and Hiroyuki Koshiyama

Another Potential Use of Troglitazone in Noninsulin-Dependent Diabetes Mellitus
J Clin Endocrinol Metab 1998 83: 1041. [Full Text]  

Hironori Yamasaki, Kiyohiro Izumino, Hirofumi Takino, Shigenobu Nagataki, and Yoshihiko Yamaguchi

Troglitazone Ameliorates Insulin Resistance in Patients with Werner’s Syndrome—Author’s Response
J Clin Endocrinol Metab 1998 83: 1041a-1042. [Full Text]  

Julio Licinio

Longitudinally Sampled Human Plasma Leptin and Cortisol Concentrations Are Inversely Correlated
J Clin Endocrinol Metab 1998 83: 1042. [Full Text]  

S. M. Haffner, H. Miettinen, P. Karhapää, L. Mykkänen, and M. Laakso

Leptin Concentrations, Sex Hormones, and Cortisol in Nondiabetic Men—Authors’ Response
J Clin Endocrinol Metab 1998 83: 1042a-1043. [Full Text]  

Gabrielle Howard, Tuan Nguyen, and Nigel Morrison

Genetic Influences on Bone Density: Physiological Correlates of Vitamin D Receptor Gene Alleles in Premenopausal Women. Notification of Genotype Corrections
J Clin Endocrinol Metab 1998 83: 1043. [Full Text]  

Philippe L. Selvais, Julian E. Donckier, Laurent Rousseau, Sylvie A. Ahn, Jean-Marie Ketelslegers, and Michel F. Rousseau

Hemodynamic Effects of Parathyroid Hormone-Related Peptide: Is There a Pathophysiological Relevance?
J Clin Endocrinol Metab 1998 83: 1043a-1044. [Full Text]  

Michael Wolzt

Hemodynamic Effects of Parathyroid Hormone-Related Peptide: Is There A Pathophysiological Relevance?—Author’s Response
J Clin Endocrinol Metab 1998 83: 1044. [Full Text]  

Claude D. Arnaud

Biochemical Markers of Bone Turnover for Predicting BMD in Early Postmenopausal Women
J Clin Endocrinol Metab 1998 83: 1044a-1045. [Full Text]  

Clifford J. Rosen

The Predictive Value of Biochemical Markers of Bone Turnover for Bone Mineral Density In Early Postmenopausal Women Treated with Hormone Replacement or Calcium Supplementation—Author’s Response
J Clin Endocrinol Metab 1998 83: 1045-1046. [Full Text]  

David J. Torpy and Constantine A. Stratakis

Linkage Analysis of Familial Hyperaldosteronism Type II—Absence of Linkage to the Gene Encoding the Angiotensin II Receptor Type 1
J Clin Endocrinol Metab 1998 83: 1046. [Full Text]  

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