Articles listed in blue may be of special interest to clinicians.

Special Articles:

Francis de Zegher, Inge Francois, monique van helvoirt, and greet van den berghe

CLINICAL REVIEW 89: Small as Fetus and Short as Child: From Endogenous to Exogenous Growth Hormone
J Clin Endocrinol Metab 1997 82: 2021-2026. [Full Text]  

Romolo Sandrini, Raul C. Ribeiro, and Luiz DeLacerda

EXTENSIVE PERSONAL EXPERIENCE: Childhood Adrenocortical Tumors
J Clin Endocrinol Metab 1997 82: 2027-2031. [Full Text]  

H. de Boer and E. A. van der Veen

EDITORIAL: Why Retest Young Adults with Childhood-Onset Growth Hormone Deficiency?
J Clin Endocrinol Metab 1997 82: 2032-2036. [Full Text]  

Clinical Studies:

Constantine A. Stratakis, Nikos A. Courcoutsakis, Andrea Abati, Armando Filie, John L. Doppman, J. Aidan Carney, and Thomas Shawker

Thyroid Gland Abnormalities in Patients with the Syndrome of Spotty Skin Pigmentation, Myxomas, Endocrine Overactivity, and Schwannomas (Carney Complex)
J Clin Endocrinol Metab 1997 82: 2037-2043. [Abstract] [Full Text]  

Jolanda M. H. Elbers, Henk Asscheman, Jacob C. Seidell, Jos A. J. Megens, and Louis J. G. Gooren

Long-Term Testosterone Administration Increases Visceral Fat in Female to Male Transsexuals
J Clin Endocrinol Metab 1997 82: 2044-2047. [Abstract] [Full Text]  

Alexander D. Zwart, Ali Iranmanesh, and Johannes D. Veldhuis

Disparate Serum Free Testosterone Concentrations and Degrees of Hypothalamo-Pituitary-Luteinizing Hormone Suppression Are Achieved by Continuous Versus Pulsatile Intravenous Androgen Replacement in Men: A Clinical Experimental Model of Ketoconazole-Induced Reversible Hypoandrogenemia with Controlled Testosterone Add-Back
J Clin Endocrinol Metab 1997 82: 2062-2069. [Abstract] [Full Text]  

S. J. Lupien, S. Gaudreau, B. M. Tchiteya, F. Maheu, S. Sharma, N. P. V. Nair, R. L. Hauger, B. S. McEwen, and M. J. Meaney

Stress-Induced Declarative Memory Impairment in Healthy Elderly Subjects: Relationship to Cortisol Reactivity
J Clin Endocrinol Metab 1997 82: 2070-2075. [Abstract] [Full Text]  

J. Argente, N. Caballo, V. Barrios, M. T. Muñoz, J. Pozo, J. A. Chowen, G. Morandé, and M. Hernández

Multiple Endocrine Abnormalities of the Growth Hormone and Insulin-Like Growth Factor Axis in Patients with Anorexia Nervosa: Effect of Short- and Long-Term Weight Recuperation
J Clin Endocrinol Metab 1997 82: 2084-2092. [Abstract] [Full Text]  

B. L. GrÉgoire Nyomba, Lori Berard, and Liam J. Murphy

Free Insulin-Like Growth Factor I (IGF-I) in Healthy Subjects: Relationship with IGF-Binding Proteins and Insulin Sensitivity
J Clin Endocrinol Metab 1997 82: 2177-2181. [Abstract] [Full Text]  

Roel DeRijk, David Michelson, Brian Karp, John Petrides, Elise Galliven, Patty Deuster, Giulio Paciotti, Philip W. Gold, and Esther M. Sternberg

Exercise and Circadian Rhythm-Induced Variations in Plasma Cortisol Differentially Regulate Interleukin-1ß (IL-1ß), IL-6, and Tumor Necrosis Factor- (TNF) Production in Humans: High Sensitivity of TNF and Resistance of IL-6
J Clin Endocrinol Metab 1997 82: 2182-2191. [Abstract] [Full Text]  

Giuseppe Paolisso, Stefania Ammendola, Andrea Del Buono, Antonio Gambardella, Mariangela Riondino, Maria Rosaria Tagliamonte, Maria Rosaria Rizzo, Carlo Carella, and Michele Varricchio

Serum Levels of Insulin-Like Growth Factor-I (IGF-I) and IGF-Binding Protein-3 in Healthy Centenarians: Relationship with Plasma Leptin and Lipid Concentrations, Insulin Action, and Cognitive Function
J Clin Endocrinol Metab 1997 82: 2204-2209. [Abstract] [Full Text]  

R. Lanzi, M. F. Manzoni, A. C. Andreotti, M. E. Malighetti, E. Bianchi, L. Piceni Sereni, A. Caumo, L. Luzi, and A. E. Pontiroli

Evidence for an Inhibitory Effect of Physiological Levels of Insulin on the Growth Hormone (GH) Response to GH-Releasing Hormone in Healthy Subjects
J Clin Endocrinol Metab 1997 82: 2239-2243. [Abstract] [Full Text]  

Lorenz C. Hofbauer, Tina Mühlberg, August König, Gabriela Heufelder, Hermann-Dieter Schworm, and Armin E. Heufelder

Soluble Interleukin-1 Receptor Antagonist Serum Levels in Smokers and Nonsmokers with Graves’ Ophthalmopathy Undergoing Orbital Radiotherapy
J Clin Endocrinol Metab 1997 82: 2244-2247. [Abstract] [Full Text]  

Masato Odawara, Yoichi Tachi, and Kamejiro Yamashita

Paraoxonase Polymorphism (Gln¹⁹²-Arg) Is Associated with Coronary Heart Disease in Japanese Noninsulin-Dependent Diabetes Mellitus
J Clin Endocrinol Metab 1997 82: 2257-2260. [Abstract] [Full Text]  

Phillip D. K. Lee, Susan K. Durham, Victor Martinez, Oswaldo Vasconez, David R. Powell, and Jaime Guevara-Aguirre

Kinetics of Insulin-Like Growth Factor (IGF) and IGF-Binding Protein Responses to a Single Dose of Growth Hormone
J Clin Endocrinol Metab 1997 82: 2266-2274. [Abstract] [Full Text]  

Susan B. Racette, Simon W. Coppack, Michael Landt, and Samuel Klein

Leptin Production during Moderate-Intensity Aerobic Exercise
J Clin Endocrinol Metab 1997 82: 2275-2277. [Abstract] [Full Text]  

V. O. Shah, R. I. Dorin, Y. Sun, M. Braun, and P. G. Zager

Aldose Reductase Gene Expression Is Increased in Diabetic Nephropathy
J Clin Endocrinol Metab 1997 82: 2294-2298. [Abstract] [Full Text]  

E. Christiansen, A. Tibell, Aa. Vølund, J. J. Holst, K. Rasmussen, L. Schäffer, and S. Madsbad

Metabolism of Oral Glucose in Pancreas Transplant Recipients with Normal and Impaired Glucose Tolerance
J Clin Endocrinol Metab 1997 82: 2299-2307. [Abstract] [Full Text]  

Eisaku Okuyama, Nozomu Nishi, Shoju Onishi, Susumu Itoh, Yoshiro Ishii, Hiroshi Miyanaka, Keinosuke Fujita, and Yoshiyuki Ichikawa

A Novel Splicing Junction Mutation in the Gene for the Steroidogenic Acute Regulatory Protein Causes Congenital Lipoid Adrenal Hyperplasia
J Clin Endocrinol Metab 1997 82: 2337-2342. [Abstract] [Full Text]  

Oliver T. Wolf, Oliver Neumann, DIRK H. HELLHAMMER, Andrea C. Geiben, Christian J. Strasburger, Regina A. Dressendörfer, Karl-Martin Pirke, and Clemens Kirschbaum

COMMENTS: Effects of a Two-Week Physiological Dehydroepiandrosterone Substitution on Cognitive Performance and Well-Being in Healthy Elderly Women and Men
J Clin Endocrinol Metab 1997 82: 2363-2367. [Abstract] [Full Text]  

Clinical Research Center Studies:

Selma F. Witchel, Peter A. Lee, Makiko Suda-Hartman, Massimo Trucco, and Eric P. Hoffman

Evidence for a Heterozygote Advantage in Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
J Clin Endocrinol Metab 1997 82: 2097-2101. [Abstract] [Full Text]  

David A. Ehrmann, David J. Schneider, Burton E. Sobel, Melissa K. Cavaghan, Jacqueline Imperial, Robert L. Rosenfield, and Kenneth S. Polonsky

Troglitazone Improves Defects in Insulin Action, Insulin Secretion, Ovarian Steroidogenesis, and Fibrinolysis in Women with Polycystic Ovary Syndrome
J Clin Endocrinol Metab 1997 82: 2108-2116. [Abstract] [Full Text]  

Steven I. Sherman, Matthew D. Ringel, Michele J. Smith, Helen A. Kopelen, William A. Zoghbi, and Paul W. Ladenson

Augmented Hepatic and Skeletal Thyromimetic Effects of Tiratricol in Comparison with Levothyroxine
J Clin Endocrinol Metab 1997 82: 2153-2158. [Abstract] [Full Text]  

Ayse Pinar Cemeroglu, Ariel L. Barkan, Gad B. Kletter, Inese Z. Beitins, and Carol M. Foster

Changes in Serum Immunoreactive and Bioactive Growth Hormone Concentrations in Boys with Advancing Puberty and in Response to a 20-Hour Estradiol Infusion
J Clin Endocrinol Metab 1997 82: 2166-2171. [Abstract] [Full Text]  

Andrew A. Toogood, Ralf M. Nass, Suzan S. Pezzoli, Paul A. O’Neill, Michael O. Thorner, and Stephen M. Shalet

Preservation of Growth Hormone Pulsatility Despite Pituitary Pathology, Surgery, and Irradiation
J Clin Endocrinol Metab 1997 82: 2215-2221. [Abstract] [Full Text]  

Endocrinological Oncology:

Etienne Delgrange, Jacqueline Trouillas, Dominique Maiter, Julian Donckier, and Jacques Tourniaire

Sex-Related Difference in the Growth of Prolactinomas: A Clinical and Proliferation Marker Study
J Clin Endocrinol Metab 1997 82: 2102-2107. [Abstract] [Full Text]  

T. H. Jones, S. K. Justice, and A. Price

Suppression of Tyrosine Kinase Activity Inhibits [³H]Thymidine Uptake in Cultured Human Pituitary Tumor Cells
J Clin Endocrinol Metab 1997 82: 2143-2147. [Abstract] [Full Text]  

Catarina Bjelfman, Torbjörn G. Söderström, Einar Brekkan, Bo Johan Norlén, Lars Egevad, Torsten Unge, Stefan Andersson, and Anders Rane

Differential Gene Expression of Steroid 5-Reductase 2 in Core Needle Biopsies from Malignant and Benign Prostatic Tissue
J Clin Endocrinol Metab 1997 82: 2210-2214. [Abstract] [Full Text]  

Alberto Falchetti, Annamaria Morelli, Andrea Amorosi, Francesco Tonelli, Silvia Fabiani, Valentina Martineti, Roberto Castello, Lino Furlani, and Maria Luisa Brandi

Allelic Loss in Parathyroid Tumors from Individuals Homozygous for Multiple Endocrine Neoplasia Type 1
J Clin Endocrinol Metab 1997 82: 2278-2282. [Abstract] [Full Text]  

Allan Flyvbjerg, Ole Mogensen, Bent Mogensen, and Ole Steen Nielsen

Elevated Serum Insulin-Like Growth Factor-Binding Protein 2 (IGFBP-2) and Decreased IGFBP-3 in Epithelial Ovarian Cancer: Correlation with Cancer Antigen 125 and Tumor-Associated Trypsin Inhibitor
J Clin Endocrinol Metab 1997 82: 2308-2313. [Abstract] [Full Text]  

Antonino Belfiore, Pietro Gangemi, Angela Costantino, Giovanna Russo, Gabriella M. Santonocito, Orazio Ippolito, Maria F. Di Renzo, Paolo Comoglio, Antonino Fiumara, and Riccardo Vigneri

Negative/Low Expression of the Met/Hepatocyte Growth Factor Receptor Identifies Papillary Thyroid Carcinomas with High Risk of Distant Metastases
J Clin Endocrinol Metab 1997 82: 2322-2328. [Abstract] [Full Text]  

J. J. Mukherjee, N. Islam, G. Kaltsas, D. G. Lowe, M. Charlesworth, F. Afshar, P. J. Trainer, J. P. Monson, G. M. Besser, and A. B. Grossman

COMMENTS: Clinical, Radiological and Pathological Features of Patients with Rathke’s Cleft Cysts: Tumors That May Recur
J Clin Endocrinol Metab 1997 82: 2357-2362. [Abstract] [Full Text]  

Experimental Studies:

R. Hoermann, C. Spitzweg, S. Poertl, K. Mann, A. E. Heufelder, and P. M. Schumm-Draeger

Regulation of Intercellular Adhesion Molecule-1 Expression in Human Thyroid Cells in Vitro and Human Thyroid Tissue Transplanted to the Nude Mouse in Vivo: Role of Graves’ Immunoglobulins and Human Thyrotropin Receptor
J Clin Endocrinol Metab 1997 82: 2048-2055. [Abstract] [Full Text]  

Mark A. Lane, Donald K. Ingram, Sheldon S. Ball, and George S. Roth

Dehydroepiandrosterone Sulfate: A Biomarker of Primate Aging Slowed by Calorie Restriction
J Clin Endocrinol Metab 1997 82: 2093-2096. [Abstract] [Full Text]  

Ayumu Kakinuma, Gregorio D. Chazenbalk, Juan Carlos Jaume, Basil Rapoport, and Sandra M. McLachlan

The Human Thyrotropin (TSH) Receptor in a TSH Binding Inhibition Assay for TSH Receptor Autoantibodies
J Clin Endocrinol Metab 1997 82: 2129-2134. [Abstract] [Full Text]  

Lane K. Christenson and Richard L. Stouffer

Follicle-Stimulating Hormone and Luteinizing Hormone/Chorionic Gonadotropin Stimulation of Vascular Endothelial Growth Factor Production by Macaque Granulosa Cells from Pre- and Periovulatory Follicles
J Clin Endocrinol Metab 1997 82: 2135-2142. [Abstract] [Full Text]  

P. C. Hindmarsh, C. H. D. Fall, P. J. Pringle, C. Osmond, and C. G. D. Brook

Peak and Trough Growth Hormone Concentrations Have Different Associations with the Insulin-Like Growth Factor Axis, Body Composition, and Metabolic Parameters
J Clin Endocrinol Metab 1997 82: 2172-2176. [Abstract] [Full Text]  

Stephen G. Somkuti, Lingwen Yuan, Marc A. Fritz, and Bruce A. Lessey

Epidermal Growth Factor and Sex Steroids Dynamically Regulate a Marker of Endometrial Receptivity in Ishikawa Cells
J Clin Endocrinol Metab 1997 82: 2192-2197. [Abstract] [Full Text]  

A.S. Dusso, S. Kamimura, M. Gallieni, M. Zhong, L. Negrea, S. Shapiro, and E. Slatopolsky

-Interferon-Induced Resistance to 1,25-(OH)₂ D₃ in Human Monocytes and Macrophages: A Mechanism for the Hypercalcemia of Various Granulomatoses
J Clin Endocrinol Metab 1997 82: 2222-2232. [Abstract] [Full Text]  

Ennian Xiao, Linna Xia-Zhang, David Shanen, and Michel Ferin

Tonic Support of Luteinizing Hormone Secretion by Adrenal Progesterone in the Ovariectomized Monkey Replaced with Midfollicular Phase Levels of Estradiol
J Clin Endocrinol Metab 1997 82: 2233-2238. [Abstract] [Full Text]  

S. Grottoli, M. Procopio, M. Maccario, M. Zini, S. E. Oleandri, F. Tassone, R. Valcavi, and E. Ghigo

In Obesity, Glucose Load Loses Its Early Inhibitory, But Maintains Its Late Stimulatory, Effect on Somatotrope Secretion
J Clin Endocrinol Metab 1997 82: 2261-2265. [Abstract] [Full Text]  

Krista Erkkilä, Kenth Henriksén, Virve Hirvonen, Sakari Rannikko, Jaakko Salo, Martti Parvinen, and Leo Dunkel

Testosterone Regulates Apoptosis in Adult Human Seminiferous Tubules in Vitro
J Clin Endocrinol Metab 1997 82: 2314-2321. [Abstract] [Full Text]  

Dejan Pavlovic, Marnix Van De Winkel, Bart Van der Auwera, Meng-Chi Chen, Frans Schuit, Luc Bouwens, and Daniel Pipeleers

Effect of Interferon- and Glucose on Major Histocompatibility Complex Class I and Class II Expression by Pancreatic ß- and Non-ß-Cells
J Clin Endocrinol Metab 1997 82: 2329-2336. [Abstract] [Full Text]  

Günter Päth, Stefan R. Bornstein, Monika Ehrhart-Bornstein, and Werner A. Scherbaum

Interleukin-6 and the Interleukin-6 Receptor in the Human Adrenal Gland: Expression and Effects on Steroidogenesis
J Clin Endocrinol Metab 1997 82: 2343-2349. [Abstract] [Full Text]  

Pediatric Endocrinology:

Hitoshi Tobiume, Susumu Kanzaki, Shigeki Hida, Taeko Ono, Tadashi Moriwake, Shigeki Yamauchi, Hiroyuki Tanaka, and Yoshiki Seino

Serum Bone Alkaline Phosphatase Isoenzyme Levels in Normal Children and Children with Growth Hormone (GH) Deficiency: A Potential Marker for Bone Formation and Response to GH Therapy
J Clin Endocrinol Metab 1997 82: 2056-2061. [Abstract] [Full Text]  

J. Argente, N. Caballo, V. Barrios, J. Pozo, M. T. Muñoz, J. A. Chowen, and M. Hernández

Multiple Endocrine Abnormalities of the Growth Hormone and Insulin-Like Growth Factor Axis in Prepubertal Children with Exogenous Obesity: Effect of Short- and Long-Term Weight Reduction
J Clin Endocrinol Metab 1997 82: 2076-2083. [Abstract] [Full Text]  

Jean-Claude Carel, Jean-Pierre Tresca, Muriel Letrait, Jean-Louis Chaussain, Yves Lebouc, Jean-Claude Job, and Joel Coste

Growth Hormone Testing for the Diagnosis of Growth Hormone Deficiency in Childhood: A Population Register-Based Study
J Clin Endocrinol Metab 1997 82: 2117-2121. [Abstract] [Full Text]  

Tim R. Nagy, Barbara A. Gower, Christina A. Trowbridge, Carl Dezenberg, Richard M. Shewchuk, and Michael I. Goran

Effects of Gender, Ethnicity, Body Composition, and Fat Distribution on Serum Leptin Concentrations in Children
J Clin Endocrinol Metab 1997 82: 2148-2152. [Abstract] [Full Text]  

Lourdes Ibáñez, Neus Potau, Maria Zampolli, Susanna RiquÉ, Paul Saenger, and Antonio Carrascosa

Hyperinsulinemia and Decreased Insulin-Like Growth Factor-Binding Protein-1 Are Common Features in Prepubertal and Pubertal Girls with a History of Premature Pubarche
J Clin Endocrinol Metab 1997 82: 2283-2288. [Abstract] [Full Text]  

Toshihiro Tajima, KENJI FUJIEDA Jun Nakae, Takio Toyoura, Kazuhiko Shimozawa, Satoshi Kusuda, Katsumi Goji, Teturo Nagashima, and Gordon B. Cutler, Jr.

COMMENTS: Molecular Basis of Nonclassical Steroid 21-Hydroxylase Deficiency Detected by Neonatal Mass Screening in Japan
J Clin Endocrinol Metab 1997 82: 2350-2356. [Abstract] [Full Text]  

Reproductive Endocrinology:

Hiroshi Fujiwara, Tetsuro Honda, Masamichi Ueda, Kimihiko Nakamura, Shigetoshi Yamada, Michiyuki Maeda, and Takahide Mori

Laminin Suppresses Progesterone Production by Human Luteinizing Granulosa Cells via Interaction with Integrin ₆ß₁
J Clin Endocrinol Metab 1997 82: 2122-2128. [Abstract] [Full Text]  

M. Misrahi, G. Meduri, S. Pissard, C. Bouvattier, I. Beau, H. Loosfelt, A. Jolivet, R. Rappaport, E. Milgrom, and P. Bougneres

Comparison of Immunocytochemical and Molecular Features with the Phenotype in a Case of Incomplete Male Pseudohermaphroditism Associated with a Mutation of the Luteinizing Hormone Receptor
J Clin Endocrinol Metab 1997 82: 2159-2165. [Abstract] [Full Text]  

Gangyi Dong, Roopmathy Rajah, Thanh Vu, Andrew R. Hoffman, Ron G. Rosenfeld, Charles T. Roberts, Jr., Donna M. Peehl, and Pinchas Cohen

Decreased Expression of Wilms’ Tumor Gene WT-1 and Elevated Expression of Insulin Growth Factor-II (IGF-II) and Type 1 IGF Receptor Genes in Prostatic Stromal Cells from Patients with Benign Prostatic Hyperplasia
J Clin Endocrinol Metab 1997 82: 2198-2203. [Abstract] [Full Text]  

Ann E. Taylor, Brian McCourt, Kathryn A. Martin, Ellen J. Anderson, Judith M. Adams, David Schoenfeld, and Janet E. Hall

Determinants of Abnormal Gonadotropin Secretion in Clinically Defined Women with Polycystic Ovary Syndrome
J Clin Endocrinol Metab 1997 82: 2248-2256. [Abstract] [Full Text]  

Eyal Y. Anteby, Roger D. Johnson, Xiahoua Huang, D. Michael Nelson, and Yoel Sadovsky

Transcriptional Regulation of Prostaglandin-H Synthase-2 Gene in Human Trophoblasts
J Clin Endocrinol Metab 1997 82: 2289-2293. [Abstract] [Full Text]  

Rapid Communications:

Peter Vorwerk, Youngman Oh, Phillip D. K. Lee, Aruna Khare, and Ron G. Rosenfeld

Synthesis of IGFBP-3 Fragments in a Baculovirus System and Characterization of Monoclonal Anti-IGFBP-3 Antibodies
J Clin Endocrinol Metab 1997 82: 2368-2370. [Abstract] [Full Text]  

Helmut Dotzlaq, Etienne Leygue, Peter H. Watson, and Leigh C. Murphy

Expression of Estrogen Receptor-ß in Human Breast Tumors
J Clin Endocrinol Metab 1997 82: 2371-2374. [Abstract] [Full Text]  

Letters to the Editor:

Barnett Zumoff

Alcohol, Estrogens, and Breast Cancer
J Clin Endocrinol Metab 1997 82: 2375-2378. [Full Text]  

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