Articles listed in blue may be of special interest to clinicians.

Special Articles:

Maria I. New

EDITORIAL: Changes in The Journal of Clinical Endocrinology and Metabolism—An Editorial from Dr. Maria I. New, Editor-in-Chief
J Clin Endocrinol Metab 1997 82: 1655 [Full Text] [PDF]  

Barnett Zumoff

EDITORIAL: The Critical Role of Alcohol Consumption in Determining the Risk of Breast Cancer with Postmenopausal Estrogen Administration
J Clin Endocrinol Metab 1997 82: 1656-1658 [Full Text] [PDF]  

Shalender Bhasin and Joyce S. Tenover

EDITORIAL: Age-Associated Sarcopenia—Issues in the Use of Testosterone as an Anabolic Agent in Older Men
J Clin Endocrinol Metab 1997 82: 1659-1660 [Full Text] [PDF]  

Beverly M. K. Biller, Brooke Swearingen, Nicholas T. Zervas, and Anne Klibanski

PROFILES OF THE ENDOCRINE CLINIC: A Decade of the Massachusetts General Hospital Neuroendocrine Clinical Center
J Clin Endocrinol Metab 1997 82: 1668-1674 [Full Text] [PDF]  

Ilan Shimon and Shlomo Melmed

GENETIC BASIS OF ENDOCRINE DISEASE: Pituitary Tumor Pathogenesis
J Clin Endocrinol Metab 1997 82: 1675-1681 [Full Text] [PDF]  

Thiemo F. Veneman and Dirk W. Erkelens

CLINICAL REVIEW 88: Hypoglycemia Unawareness in Noninsulin-Dependent Diabetes Mellitus
J Clin Endocrinol Metab 1997 82: 1682-1684 [Full Text] [PDF]  

Jose F. Caro

EDITORIAL: Leptin Is Normal in PCOS, An Editorial about Three "Negative" Papers
J Clin Endocrinol Metab 1997 82: 1685-1686 [Full Text] [PDF]  

Delbert A. Fisher

EDITORIAL: The Hypothroxinemia of Prematurity
J Clin Endocrinol Metab 1997 82: 1701-1703 [Full Text] [PDF]  

Randall B. Barnes and David A. Ehrmann

CLINICAL CASE SEMINAR: Long-Term Suppression of Testosterone After Treatment with a Gonadotropin-Releasing Hormone Agonist in a Woman with a Presumed Testosterone Secreting Ovarian Tumor
J Clin Endocrinol Metab 1997 82: 1746-1748 [Full Text] [PDF]  

Mohamad Maghnie, Eugenio Genovese, Stefan Lundin, Federico Bonetti, and Maurizio Aricò

CLINICAL CASE SEMINAR: Hyatrogenic Extrapontine Myelinolysis in Central Diabetes Insipidus: Are Cyclosporine and 1-Desamino-8-D-Arginine Vasopressin Harmful in Association?
J Clin Endocrinol Metab 1997 82: 1749-1751 [Full Text] [PDF]  

Reproductive Endocrinology:

Rahmawati Sih, John E. Morley, Fran E. Kaiser, Horace M. Perry, III, Ping Patrick, and Candie Ross

Testosterone Replacement in Older Hypogonadal Men: A 12-Month Randomized Controlled Trial
J Clin Endocrinol Metab 1997 82: 1661-1667 [Abstract] [Full Text] [PDF]  

Christos S. Mantzoros, Andrea Dunaif, and Jeffrey S. Flier

Leptin Concentrations in the Polycystic Ovary Syndrome
J Clin Endocrinol Metab 1997 82: 1687-1691 [Abstract] [Full Text] [PDF]  

G. A. Laughlin, A. J. Morales, and S. S. C. Yen

Serum Leptin Levels in Women with Polycystic Ovary Syndrome: The Role of Insulin Resistance/ Hyperinsulinemia
J Clin Endocrinol Metab 1997 82: 1692-1696 [Abstract] [Full Text] [PDF]  

Juha Rouru, Leena Anttila, Pertti Koskinen, Tuula-Anneli Penttilä, Kerttu Irjala, Risto Huupponen, and Markku Koulu

Serum Leptin Concentrations in Women with Polycystic Ovary Syndrome
J Clin Endocrinol Metab 1997 82: 1697-1700 [Abstract] [Full Text] [PDF]  

N. A. Martina, E. Kim, U. Chitkara, N. C. Wathen, T. Chard, and L. C. Giudice

Gestational Age-Dependent Expression of Insulin-Like Growth Factor-Binding Protein-1 (IGFBP-1) Phosphoisoforms in Human Extraembryonic Cavities, Maternal Serum, and Decidua Suggests Decidua as the Primary Source of IGFBP-1 in these Fluids during Early Pregnancy
J Clin Endocrinol Metab 1997 82: 1894-1898 [Abstract] [Full Text] [PDF]  

Pascal Pigny, Rachel Desailloud, Christine Cortet-Rudelli, Alain Duhamel, Delphine Deroubaix-Allard, André Racadot, and Didier Dewailly

Serum -Inhibin Levels in Polycystic Ovary Syndrome: Relationship to the Serum Androstenedione Level
J Clin Endocrinol Metab 1997 82: 1939-1943 [Abstract] [Full Text] [PDF]  

Michael J. McPhaul, Hans-Udo Schweikert, and Diane R. Allman

Assessment of Androgen Receptor Function in Genital Skin Fibroblasts Using a Recombinant Adenovirus to Deliver an Androgen-Responsive Reporter Gene
J Clin Endocrinol Metab 1997 82: 1944-1948 [Abstract] [Full Text] [PDF]  

Radmila Runic, Frederick Schatz, Lewis Krey, Rita Demopoulos, Stephen Thung, Livia Wan, and Charles J. Lockwood

Alterations in Endometrial Stromal Cell Tissue Factor Protein and Messenger Ribonucleic Acid Expression in Patients Experiencing Abnormal Uterine Bleeding While Using Norplant-2 Contraception
J Clin Endocrinol Metab 1997 82: 1983-1988 [Abstract] [Full Text] [PDF]  

Pediatric Endocrinology:

Susana Ares, Héctor F. Escobar-Morreale, José Quero, Socorro Durán, María Jesus Presas, Rafael Herruzo, and Gabriella Morreale de Escobar

Neonatal Hypothyroxinemia: Effects of Iodine Intake and Premature Birth
J Clin Endocrinol Metab 1997 82: 1704-1712 [Abstract] [Full Text] [PDF]  

Nicole S. Glaser and Dennis M. Styne

Predictors of Early Remission of Hyperthyroidism in Children
J Clin Endocrinol Metab 1997 82: 1719-1726 [Abstract] [Full Text] [PDF]  

Maria Alexandra Magiakou, George Mastorakos, Keith Zachman, and George P. Chrousos

Blood Pressure in Children and Adolescents with Cushing’s Syndrome before and after Surgical Cure
J Clin Endocrinol Metab 1997 82: 1734-1738 [Abstract] [Full Text] [PDF]  

Primus E. Mullis, Noriko Yoshimura, Beatrice Kuhlmann, Kurt Lippuner, Philippe Jaeger, and Hobuhiro Harada

Aromatase Deficiency in a Female Who Is Compound Heterozygote for Two New Point Mutations in the P450_arom Gene: Impact of Estrogens on Hypergonadotropic Hypogonadism, Multicystic Ovaries, and Bone Densitometry in Childhood
J Clin Endocrinol Metab 1997 82: 1739-1745 [Abstract] [Full Text] [PDF]  

Anna Maria Pasquino, Franca Passeri, Ida Pucarelli, Maria Segni, and Giovanna Municchi

Spontaneous Pubertal Development in Turner’s Syndrome
J Clin Endocrinol Metab 1997 82: 1810-1813 [Abstract] [Full Text] [PDF]  

Judith L. Ross, Penelope Feuillan, Harvey Kushner, David Roeltgen, and Gordon B. Cutler, Jr.

Absence of Growth Hormone Effects on Cognitive Function in Girls with Turner Syndrome
J Clin Endocrinol Metab 1997 82: 1814-1817 [Abstract] [Full Text] [PDF]  

Ross Barnard, Fung-yee Chan, and H. David McIntyre

Growth Hormone-Binding Protein in Normal and Pathologic Gestation: Correlations with Maternal Diabetes and Fetal Growth
J Clin Endocrinol Metab 1997 82: 1879-1884 [Abstract] [Full Text] [PDF]  

Jean-Pierre Bourguignon, Jaak Jaeken, Arlette Gerard, and Francis de Zegher

Amino Acid Neurotransmission and Initiation of Puberty: Evidence from Nonketotic Hyperglycinemia in a Female Infant and Gonadotropin-Releasing Hormone Secretion by Rat Hypothalamic Explants
J Clin Endocrinol Metab 1997 82: 1899-1903 [Abstract] [Full Text] [PDF]  

Silva Arslanian, Chittiwat Suprasongsin, and Janine E. Janosky

Insulin Secretion and Sensitivity in Black Versus White Prepubertal Healthy Children
J Clin Endocrinol Metab 1997 82: 1923-1927 [Abstract] [Full Text] [PDF]  

R. Ravi Shankar, Regina I. Jakacki, Anzar Haider, Melissa W. Lee, and Ora Hirsch Pescovitz

COMMENTS: Testing the Hypothalamic-Pituitary-Adrenal Axis in Survivors of Childhood Brain and Skull-Based Tumors
J Clin Endocrinol Metab 1997 82: 1995-1998 [Abstract] [Full Text] [PDF]  

Clinical Studies:

Timothy W. Jones, Walter P. Borg, Monica A. Borg, Susan D. Boulware, Gregory McCarthy, David Silver, William V. Tamborlane, and Robert S. Sherwin

Resistance to Neuroglycopenia: An Adaptative Response during Intensive Insulin Treatment of Diabetes
J Clin Endocrinol Metab 1997 82: 1713-1718 [Abstract] [Full Text] [PDF]  

Katherine V. Williams, Sunil Nayak, Dorothy Becker, Jorge Reyes, and Lynn A. Burmeister

Fifty Years of Experience with Propylthiouracil-Associated Hepatotoxicity: What Have We Learned?
J Clin Endocrinol Metab 1997 82: 1727-1733 [Abstract] [Full Text] [PDF]  

Nina Hannover Bjarnason, Ketil Bjarnason, Jens Haarbo, Herjan J.T. Coelingh Bennink, and Claus Christiansen

Tibolone: Influence on Markers of Cardiovascular Disease
J Clin Endocrinol Metab 1997 82: 1752-1756 [Abstract] [Full Text] [PDF]  

Motoshi Okumura, Yoh Hidaka, Shoko Kuroda, Keiko Takeoka, Hisato Tada, and Nobuyuki Amino

Increased Serum Concentration of Soluble CD30 in Patients with Graves’ Disease and Hashimoto’s Thyroiditis
J Clin Endocrinol Metab 1997 82: 1757-1760 [Abstract] [Full Text] [PDF]  

Kathryn E. Graham, Mary H. Samuels, Hershel Raff, Stanley L. Barnwell, and David M. Cook

Intraoperative Adrenocorticotropin Levels During Transsphenoidal Surgery for Cushing’s Disease Do Not Predict Cure
J Clin Endocrinol Metab 1997 82: 1776-1779 [Abstract] [Full Text] [PDF]  

David C. Aron, Hershel Raff, and James W. Findling

Effectiveness Versus Efficacy: The Limited Value in Clinical Practice of High Dose Dexamethasone Suppression Testing in the Differential Diagnosis of Adrenocorticotropin-Dependent Cushing’s Syndrome
J Clin Endocrinol Metab 1997 82: 1780-1785 [Abstract] [Full Text] [PDF]  

Steven M. Haffner, Heikki Miettinen, Pauli Karhapää, Leena Mykkänen, and Markku Laakso

Leptin Concentrations, Sex Hormones, and Cortisol in Nondiabetic Men
J Clin Endocrinol Metab 1997 82: 1807-1809 [Abstract] [Full Text] [PDF]  

Takako Saito, San-e Ishikawa, Sei Sasaki, Tomoatsu Nakamura, Kumiko Rokkaku, Akio Kawakami, Kazufumi Honda, Fumiaki Marumo, and Toshikazu Saito

Urinary Excretion of Aquaporin-2 in the Diagnosis of Central Diabetes Insipidus
J Clin Endocrinol Metab 1997 82: 1823-1827 [Abstract] [Full Text] [PDF]  

Clare N. O. Jones, Dee Pei, Patricia Staris, Kenneth S. Polonsky, Y. D.-Ida Chen, and Gerald M. Reaven

Alterations in the Glucose-Stimulated Insulin Secretory Dose-Response Curve and in Insulin Clearance in Nondiabetic Insulin-Resistant Individuals
J Clin Endocrinol Metab 1997 82: 1834-1838 [Abstract] [Full Text] [PDF]  

Christos Mantzoros, Jeffrey S. Flier, Michael D. Lesem, Timothy D. Brewerton, and David C. Jimerson

Cerebrospinal Fluid Leptin in Anorexia Nervosa: Correlation with Nutritional Status and Potential Role in Resistance to Weight Gain
J Clin Endocrinol Metab 1997 82: 1845-1851 [Abstract] [Full Text] [PDF]  

Jack A. Yanovski, Susan Zelitch Yanovski, Philip W. Gold, and George P. Chrousos

Differences in Corticotropin-Releasing Hormone-Stimulated Adrenocorticotropin and Cortisol before and after Weight Loss
J Clin Endocrinol Metab 1997 82: 1874-1878 [Abstract] [Full Text] [PDF]  

Clifford J. Rosen, Charles H. Chesnut, III, and Nancy J. S. Mallinak

The Predictive Value of Biochemical Markers of Bone Turnover for Bone Mineral Density in Early Postmenopausal Women Treated with Hormone Replacement or Calcium Supplementation
J Clin Endocrinol Metab 1997 82: 1904-1910 [Abstract] [Full Text] [PDF]  

Won Bae Kim, Hyun Kyung Chung, Hong Kyu Lee, Leonard D. Kohn, Kazuo Tahara, and Bo Youn Cho

Changes in Epitopes for Thyroid-Stimulating Antibodies in Graves’ Disease Sera During Treatment of Hyperthyroidism: Therapeutic Implications
J Clin Endocrinol Metab 1997 82: 1953-1959 [Abstract] [Full Text] [PDF]  

Esteban Jódar, Manuel Muñoz-Torres, Fernando Escobar-Jiménez, Miguel Quesada, Juan D. Luna, and Nicolás Olea

Antiresorptive Therapy in Hyperthyroid Patients: Longitudinal Changes in Bone and Mineral Metabolism
J Clin Endocrinol Metab 1997 82: 1989-1994 [Abstract] [Full Text] [PDF]  

Experimental Studies:

M. Barbagallo, R. K. Gupta, O. Bardicef, M. Bardicef, and L. M. Resnick

Altered Ionic Effects of Insulin in Hypertension: Role of Basal Ion Levels in Determining Cellular Responsiveness
J Clin Endocrinol Metab 1997 82: 1761-1765 [Abstract] [Full Text] [PDF]  

Tobias Carling, Peter Ridefelt, Per Hellman, Jonas Rastad, and Göran Åkerström

Vitamin D Receptor Polymorphisms Correlate to Parathyroid Cell Function in Primary Hyperparathyroidism
J Clin Endocrinol Metab 1997 82: 1772-1775 [Abstract] [Full Text] [PDF]  

Søren A. Urhammer, Torben Hansen, Liselotte Brix Jensen, Jesper O. Clausen, Lars Hansen, Ken C. Chui, and Oluf Pedersen

Studies of the Impact of a Liver Glucokinase Promoter Variant on Glucose Tolerance and Insulin Sensitivity Index
J Clin Endocrinol Metab 1997 82: 1786-1789 [Abstract] [Full Text] [PDF]  

Meera S. Ramayya, Jian Zhou, Tomoshige Kino, James H. Segars, Carolyn A. Bondy, and George P. Chrousos

Steroidogenic Factor 1 Messenger Ribonucleic Acid Expression in Steroidogenic and Nonsteroidogenic Human Tissues: Northern Blot and in Situ Hybridization Studies
J Clin Endocrinol Metab 1997 82: 1799-1806 [Abstract] [Full Text] [PDF]  

Nathalie Bravenboer, Paulien Holzmann, Hans de Boer, Jan C. Roos, Eduard A. van der Veen, and Paul Lips

The Effect of Growth Hormone (GH) on Histomorphometric Indices of Bone Structure and Bone Turnover in GH-Deficient Men
J Clin Endocrinol Metab 1997 82: 1818-1822 [Abstract] [Full Text] [PDF]  

Steven Wise, Michael Nielsen, and Robert Rizza

Effects of Hepatic Glycogen Content on Hepatic Insulin Action in Humans: Alteration in the Relative Contributions of Glycogenolysis and Gluconeogenesis to Endogenous Glucose Production
J Clin Endocrinol Metab 1997 82: 1828-1833 [Abstract] [Full Text] [PDF]  

R. Heinrich and Z. Kraiem

The Protein Kinase A Pathway Inhibits c-jun and c-fos Protooncogene Expression Induced by the Protein Kinase C and Tyrosine Kinase Pathways in Cultured Human Thyroid Follicles
J Clin Endocrinol Metab 1997 82: 1839-1844 [Abstract] [Full Text] [PDF]  

Gillian M. Beattie, Vincenzo Cirulli, Ana D. Lopez, and Alberto Hayek

Ex Vivo Expansion of Human Pancreatic Endocrine Cells
J Clin Endocrinol Metab 1997 82: 1852-1856 [Abstract] [Full Text] [PDF]  

Su Xu, Paul Savage, John L. Burton, Jane Sansom, and Jeffrey M. P. Holly

Proteolysis of Insulin-Like Growth Factor-Binding Protein-3 by Human Skin Keratinocytes in Culture in Comparison to that in Skin Interstitial Fluid: The Role and Regulation of Components of the Plasmin System
J Clin Endocrinol Metab 1997 82: 1863-1868 [Abstract] [Full Text] [PDF]  

S. Goldman, M. Dirnfeld, H. Abramovici, and Z. Kraiem

Triiodothyronine and Follicle-Stimulating Hormone, Alone and Additively Together, Stimulate Production of the Tissue Inhibitor of Metalloproteinases-1 in Cultured Human Luteinized Granulosa Cells
J Clin Endocrinol Metab 1997 82: 1869-1873 [Abstract] [Full Text] [PDF]  

Sai A. Patibandla, John S. Dallas, Gattadahalli S. Seetharamaiah, Kazuo Tahara, Leonard D. Kohn, and Bellur S. Prabhakar

Flow Cytometric Analyses of Antibody Binding to Chinese Hamster Ovary Cells Expressing Human Thyrotropin Receptor
J Clin Endocrinol Metab 1997 82: 1885-1893 [Abstract] [Full Text] [PDF]  

William E. Connor, Don S. Lin, and Martha Neuringer

Biochemical Markers for Puberty in the Monkey Testis: Desmosterol and Docosahexaenoic Acid
J Clin Endocrinol Metab 1997 82: 1911-1916 [Abstract] [Full Text] [PDF]  

David R. Mann, Mukaila A. Akinbami, Kim Wallen, Kenneth G. Gould, Nigel P. Groome, Ian Swanston, Alan S. McNeilly, and Hamish M. Fraser

Inhibin-B in the Male Rhesus Monkey: Impact of Neonatal Gonadotropin-Releasing Hormone Antagonist Treatment and Sexual Development
J Clin Endocrinol Metab 1997 82: 1928-1933 [Abstract] [Full Text] [PDF]  

Hideki Yamaguchi, Masamitsu Nakazato, Mikiya Miyazato, Kenji Kangawa, and Shigeru Matsukura

A 5'-Splice Site Mutation in the Cytochrome P450 Steroid 17-Hydroxylase Gene in 17-Hydroxylase Deficiency
J Clin Endocrinol Metab 1997 82: 1934-1938 [Abstract] [Full Text] [PDF]  

Kanji Sato, Megumi Miyakawa, Noritaka Onoda, Hiroshi Demura, Tetsuji Yamashita, Masakazu Miura, Takeshi Kasajima, Kazuko Yamazaki, and Takao Obara

Increased Concentration of Vascular Endothelial Growth Factor/Vascular Permeability Factor in Cyst Fluid of Enlarging and Recurrent Thyroid Nodules
J Clin Endocrinol Metab 1997 82: 1968-1973 [Abstract] [Full Text] [PDF]  

Endocrinological Oncology:

Jianqi Liu, Arvi I. Kahri, Päivi Heikkilä, and Raimo Voutilainen

Ribonucleic Acid Expression of the Clustered Imprinted Genes, p57^KIP2, Insulin-Like Growth Factor II, and H19, in Adrenal Tumors and Cultured Adrenal Cells
J Clin Endocrinol Metab 1997 82: 1766-1771 [Abstract] [Full Text] [PDF]  

Rama Natarajan, Robert Esworthy, Wei Bai, Jia-Li Gu, Sharon Wilczynski, and Jerry Nadler

Increased 12-Lipoxygenase Expression in Breast Cancer Tissues and Cells. Regulation by Epidermal Growth Factor
J Clin Endocrinol Metab 1997 82: 1790-1798 [Abstract] [Full Text] [PDF]  

Kenneth B. Ain, Kimberly D. Taylor, Sharmen Tofiq, and Gopalakrishnan Venkataraman

Somatostatin Receptor Subtype Expression in Human Thyroid and Thyroid Carcinoma Cell Lines
J Clin Endocrinol Metab 1997 82: 1857-1862 [Abstract] [Full Text] [PDF]  

Christian F. Singer, Audrey Rasmussen, Marc E. Lippman, and Kevin J. Cullen

Coexpression of Stromelysin-3 and Insulin-Like Growth Factor II in Tumors of Ectodermal, Mesodermal, and Endodermal Origin: Indicator of a Fetal Cell Phenotype
J Clin Endocrinol Metab 1997 82: 1917-1922 [Abstract] [Full Text] [PDF]  

Da-Gong Wang, Colin F. Johnston, John J. Marley, Kerry V. Phenix, A. Brew Atkinson, Colin F. J. Russell, and Keith D. Buchanan

Expression of the Apoptosis-Suppressing Gene BCL-2 in Pheochromocytoma is Associated with the Expression of C-MYC
J Clin Endocrinol Metab 1997 82: 1949-1952 [Abstract] [Full Text] [PDF]  

Neil J. L. Gittoes, Christopher J. McCabe, Julie Verhaeg, Michael C. Sheppard, and Jayne A. Franklyn

Thyroid Hormone and Estrogen Receptor Expression in Normal Pituitary and Nonfunctioning Tumors of the Anterior Pituitary
J Clin Endocrinol Metab 1997 82: 1960-1967 [Abstract] [Full Text] [PDF]  

Naoko Sanno, Long Jin, Xiang Qian, R. Yoshiyuki Osamura, Bernd W. Scheithauer, Kalman Kovacs, and Ricardo V. Lloyd

Gonadotropin-Releasing Hormone and Gonadotropin-Releasing Hormone Receptor Messenger Ribonucleic Acids Expression in Nontumorous and Neoplastic Pituitaries
J Clin Endocrinol Metab 1997 82: 1974-1982 [Abstract] [Full Text] [PDF]  

Letters to the Editor:

William Rosner

Errors in the Measurement of Plasma Free Testosterone
J Clin Endocrinol Metab 1997 82: 2014-2015 [Full Text] [PDF]  

John E. Nestler

Errors in the Measurement of Plasma Free Testosterone—Author’s Response
J Clin Endocrinol Metab 1997 82: 2015 [Full Text] [PDF]  

F. Cetta, G. Montalto, M. Petracci, and A. Fusco

Thyroid Cancer and the Chernobyl Accident. Are Long-Term and Long Distance Side Effects of FallOut Radiation Greater Than Estimated?
J Clin Endocrinol Metab 1997 82: 2015-a-2016 [Full Text] [PDF]  

Yuri E. Nikiforov and James A. Fagin

Prevalence, Significance, and Biological Behavior of ret/PTC Associated Papillary Thyroid Carcinoma— Author’s Response
J Clin Endocrinol Metab 1997 82: 2016-2017 [Full Text] [PDF]  

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