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Contents: Volume 82, Issue 11   [Index by Author]       Other Issues:  
       Special Articles
       From the Clinical Research Centers
       Original Studies
       Rapid Communications
       Letters to the Editor
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Articles listed in blue may be of special interest to clinicians.

Special Articles:

Michael Peter, Lubna Fawaz, Stenvert L. S. Drop, Hendrik K. A. Visser, and Wolfgang G. Sippell
A PRISMATIC CASE: Hereditary Defect in Biosynthesis of Aldosterone: Aldosterone Synthase Deficiency 1964–1997
J Clin Endocrinol Metab 1997 82: 3525-3528. [Abstract] [Full Text]  

Katie A. Woods, Florence Dastot, Michael A. Preece, Adrian J. L. Clark, Marie-Catherine Postel-Vinay, Pierre G. Chatelain, Michael B. Ranke, Ron G. Rosenfeld, Serge Amselem, and Martin O. Savage
EXTENSIVE PERSONAL EXPERIENCE: Phenotype: Genotype Relationships in Growth Hormone Insensitivity Syndrome
J Clin Endocrinol Metab 1997 82: 3529-3535. [Abstract] [Full Text]  

Mark C. Eddy, Rattana Leelawattana, William H. McAlister, and Michael P. Whyte
CLINICAL CASE SEMINAR: Calcinosis Universalis Complicating Juvenile Dermatomyositis: Resolution During Probenecid Therapy
J Clin Endocrinol Metab 1997 82: 3536-3542. [Full Text]  

From the Clinical Research Centers:

O. Khorram, M. Yeung, L. Vu, and S. S. C. Yen
Effects of [Norleucine27]Growth Hormone-Releasing Hormone (GHRH) (1–29)-NH2 Administration on the Immune System of Aging Men and Women
J Clin Endocrinol Metab 1997 82: 3590-3596. [Abstract] [Full Text]  

M. H. Samuels and P. A. McDaniel
Thyrotropin Levels during Hydrocortisone Infusions That Mimic Fasting-Induced Cortisol Elevations: A Clinical Research Center Study
J Clin Endocrinol Metab 1997 82: 3700-3704. [Abstract] [Full Text]  

David A. Fryburg, Arthur Weltman, Linda A. Jahn, Judy Y. Weltman, Eugene Samojlik, Raymond L. Hintz, and Johannes D. Veldhuis
Short-Term Modulation of the Androgen Milieu Alters Pulsatile, But Not Exercise- or Growth Hormone (GH)-Releasing Hormone-Stimulated GH Secretion in Healthy Men: Impact of Gonadal Steroid and GH Secretory Changes on Metabolic Outcomes
J Clin Endocrinol Metab 1997 82: 3710-3719. [Abstract] [Full Text]  

Carl Grunfeld, William Doerrler, Miyin Pang, Peter Jensen, Karl H. Weisgraber, and Kenneth R. Feingold
Abnormalities of Apolipoprotein E in the Acquired Immunodeficiency Syndrome
J Clin Endocrinol Metab 1997 82: 3734-3740. [Abstract] [Full Text]  

Konstantinos Ziambaras, William A. Totty, Steven L. Teitelbaum, Megan Dierkes, and Michael P. Whyte
Extraskeletal Osteoclastomas Responsive to Dexamethasone Treatment in Paget Bone Disease
J Clin Endocrinol Metab 1997 82: 3826-3834. [Abstract] [Full Text]  

Original Studies:

V. Mijatovic, P. Kenemans, J. C. Netelenbos, E. R. A. Peters-Muller, G. J. van Kamp, G. A. Voetberg, P. H. M. van de Weijer, and M. J. van der Mooren
Oral 17ß-Estradiol Continuously Combined with Dydrogesterone Lowers Serum Lipoprotein(a) Concentrations in Healthy Postmenopausal Women
J Clin Endocrinol Metab 1997 82: 3543-3547. [Abstract] [Full Text]  

P. C. Ng, G. W. K. Wong, C. W. K. Lam, C. H. Lee, M. Y. Wong, T. F. Fok, W. Wong, and D. C. F. Chan
Pituitary-Adrenal Response in Preterm Very Low Birth Weight Infants after Treatment with Antenatal Corticosteroids
J Clin Endocrinol Metab 1997 82: 3548-3552. [Abstract] [Full Text]  

Keh-Chuan Loh, Francis S. Greenspan, Lauren Gee, Theodore R. Miller, and Peter P. B. Yeo
Pathological Tumor-Node-Metastasis (pTNM) Staging for Papillary and Follicular Thyroid Carcinomas: A Retrospective Analysis of 700 Patients
J Clin Endocrinol Metab 1997 82: 3553-3562. [Abstract] [Full Text]  

Furio Pacini, Tatiana Vorontsova, Eugeni P. Demidchik, Eleonora Molinaro, Laura Agate, Cristina Romei, Elena Shavrova, Eugeny D. Cherstvoy, Yuriy Ivashkevitch, Elvira Kuchinskaya, Martin Schlumberger, Giuseppe Ronga, Mauro Filesi, and Aldo Pinchera
Post-Chernobyl Thyroid Carcinoma in Belarus Children and Adolescents: Comparison with Naturally Occurring Thyroid Carcinoma in Italy and France
J Clin Endocrinol Metab 1997 82: 3563-3569. [Abstract] [Full Text]  

W. Reid Litchfield, Maria I. New, Caroline Coolidge, Richard P. Lifton, and Robert G. Dluhy
Evaluation of the Dexamethasone Suppression Test for the Diagnosis of Glucocorticoid-Remediable Aldosteronism
J Clin Endocrinol Metab 1997 82: 3570-3573. [Abstract] [Full Text]  

Annamaria Colao, Antonella Di Sarno, Maria Luisa Landi, Sossio Cirillo, Francesca Sarnacchiaro, Giuseppina Facciolli, Rosario Pivonello, Mauro Cataldi, Bartolomeo Merola, Lucio Annunziato, and Gaetano Lombardi
Long-Term and Low-Dose Treatment with Cabergoline Induces Macroprolactinoma Shrinkage
J Clin Endocrinol Metab 1997 82: 3574-3579. [Abstract] [Full Text]  

Brandon J. Orr-Walker, Margaret C. Evans, Ruth W. Ames, Judith M. Clearwater, and Ian R. Reid
Premature Hair Graying and Bone Mineral Density
J Clin Endocrinol Metab 1997 82: 3580-3583. [Abstract] [Full Text]  

Paul-Martin Holterhus, Hennie T. Brüggenwirth, Olaf Hiort, Annette Kleinkauf-Houcken, Klaus Kruse, Gernot H. G. Sinnecker, and Albert O. Brinkmann
Mosaicism due to a Somatic Mutation of the Androgen Receptor Gene Determines Phenotype in Androgen Insensitivity Syndrome
J Clin Endocrinol Metab 1997 82: 3584-3589. [Abstract] [Full Text]  

Evert J. P. van Santbrink and Bart C. J. M. Fauser
Urinary Follicle-Stimulating Hormone for Normogonadotropic Clomiphene-Resistant Anovulatory Infertility: Prospective, Randomized Comparison between Low Dose Step-Up and Step-Down Dose Regimens
J Clin Endocrinol Metab 1997 82: 3597-3602. [Abstract] [Full Text]  

Masao Jinno, Yuuko Katsumata, Toshihisa Hoshiai, Yukio Nakamura, Kazuya Matsumoto, and Yasunori Yoshimura
A Therapeutic Role of Prolactin Supplementation in Ovarian Stimulation for in Vitro Fertilization: The Bromocriptine-Rebound Method
J Clin Endocrinol Metab 1997 82: 3603-3611. [Abstract] [Full Text]  

Nina Vahl, Niels Møller, Torsten Lauritzen, Jens S. Christiansen, and Jens O. L. Jørgensen
Metabolic Effects and Pharmacokinetics of a Growth Hormone Pulse in Healthy Adults: Relation to Age, Sex, and Body Composition
J Clin Endocrinol Metab 1997 82: 3612-3618. [Abstract] [Full Text]  

Giovanni Targher, Maria Alberiche, Marina B. Zenere, Riccardo C. Bonadonna, Michele Muggeo, and Enzo Bonora
Cigarette Smoking and Insulin Resistance in Patients with Noninsulin-Dependent Diabetes Mellitus
J Clin Endocrinol Metab 1997 82: 3619-3624. [Abstract] [Full Text]  

Joseph T. King, Jr., Amy C. Justice, and David C. Aron
Management of Incidental Pituitary Microadenomas: A Cost-Effectiveness Analysis
J Clin Endocrinol Metab 1997 82: 3625-3632. [Abstract] [Full Text]  

Naoko Momotani, Jaeduk Yoshimura Noh, Naofumi Ishikawa, and Kunihiko Ito
Effects of Propylthiouracil and Methimazole on Fetal Thyroid Status in Mothers with Graves’ Hyperthyroidism
J Clin Endocrinol Metab 1997 82: 3633-3636. [Abstract] [Full Text]  

Alice C. Chiu, Ebrahim S. Delpassand, and Steven I. Sherman
Prognosis and Treatment of Brain Metastases in Thyroid Carcinoma
J Clin Endocrinol Metab 1997 82: 3637-3642. [Abstract] [Full Text]  

Priscila C. Gagliardi, Sergio Bernasconi, and David R. Repaske
Autosomal Dominant Neurohypophyseal Diabetes Insipidus Associated with a Missense Mutation Encoding Gly23->Val in Neurophysin II
J Clin Endocrinol Metab 1997 82: 3643-3646. [Abstract] [Full Text]  

Michael Rosenbaum, Margery Nicolson, Jules Hirsch, Ellen Murphy, Florence Chu, and Rudolph L. Leibel
Effects of Weight Change on Plasma Leptin Concentrations and Energy Expenditure
J Clin Endocrinol Metab 1997 82: 3647-3654. [Abstract] [Full Text]  

Maria Elena Fisfalen, Ellen M. Palmer, Gijs A. van Seventer, Keyoumars Soltani, Yoshikuni Sawai, Edwin Kaplan, Yoh Hidaka, Carole Ober, and Leslie J. DeGroot
Thyrotropin-Receptor and Thyroid Peroxidase-Specific T Cell Clones and Their Cytokine Profile in Autoimmune Thyroid Disease
J Clin Endocrinol Metab 1997 82: 3655-3663. [Abstract] [Full Text]  

Fernando Larrea, Araceli Martínez-Castillo, Victor Cabrera, Jorge Alcocer-Varela, Gloria Queipo, Cecilia Cariño, and Donato Alarcón-Segovia
A Bioactive 60-Kilodalton Prolactin Species Is Preferentially Secreted in Cultures of Mitogen-Stimulated and Nonstimulated Peripheral Blood Mononuclear Cells from Subjects with Systemic Lupus Erythematosus
J Clin Endocrinol Metab 1997 82: 3664-3669. [Abstract] [Full Text]  

Michael Stowasser, Michael G. Gartside, Wendy L. Taylor, Terry J. Tunny, and Richard D. Gordon
In Familial Hyperaldosteronism Type I, Hybrid Gene-Induced Aldosterone Production Dominates That Induced by Wild-Type Genes
J Clin Endocrinol Metab 1997 82: 3670-3676. [Abstract] [Full Text]  

Lucia Ghizzoni, George Mastorakos, Maria E. Street, Alessandra Vottero, Gemma Mazzardo, Maurizio Vanelli, George P. Chrousos, and Sergio Bernasconi
Spontaneous Thyrotropin and Cortisol Secretion Interactions in Patients with Nonclassical 21-Hydroxylase Deficiency and Control Children
J Clin Endocrinol Metab 1997 82: 3677-3683. [Abstract] [Full Text]  

Stefan K. G. Grebe, Bryan McIver, Ian D. Hay, Patricia S.-C. Wu, Lea M. Z. Maciel, Harry A. Drabkin, John R. Goellner, Clive S. Grant, Robert B. Jenkins, and Norman L. Eberhardt
Frequent Loss of Heterozygosity on Chromosomes 3p and 17p without VHL or p53 Mutations Suggests Involvement of Unidentified Tumor Suppressor Genes in Follicular Thyroid Carcinoma
J Clin Endocrinol Metab 1997 82: 3684-3691. [Abstract] [Full Text]  

Christopher J. Ormandy, Rosemary E. Hall, David L. Manning, John F. R. Robertson, Roger W. Blamey, Paul A. Kelly, Robert I. Nicholson, and Robert L. Sutherland
Coexpression and Cross-Regulation of the Prolactin Receptor and Sex Steroid Hormone Receptors in Breast Cancer
J Clin Endocrinol Metab 1997 82: 3692-3699. [Abstract] [Full Text]  

Hidesuke Kaji, Osamu Nose, Hitoshi Tajiri, Yutaka Takahashi, Keiji Iida, Tetsuya Takahashi, Yasuhiko Okimura, Hiromi Abe, and Kazuo Chihara
Novel Compound Heterozygous Mutations of Growth Hormone (GH) Receptor Gene in a Patient with GH Insensitivity Syndrome
J Clin Endocrinol Metab 1997 82: 3705-3709. [Abstract] [Full Text]  

Corrine K. Welt, Geralyn Lambert-Messerlian, Wenxin Zheng, William F. Crowley, Jr., and Alan L. Schneyer
Presence of Activin, Inhibin, and Follistatin in Epithelial Ovarian Carcinoma
J Clin Endocrinol Metab 1997 82: 3720-3727. [Abstract] [Full Text]  

A. Arroyo, G. A. Laughlin, A. J. Morales, and S. S. C. Yen
Inappropriate Gonadotropin Secretion in Polycystic Ovary Syndrome: Influence of Adiposity
J Clin Endocrinol Metab 1997 82: 3728-3733. [Abstract] [Full Text]  

Euy Y. Soh, Quan-Yang Duh, Saif A. Sobhi, Dave M. Young, Howard D. Epstein, Mariwil G. Wong, Y. Kit Garcia, Young D. Min, Richard F. Grossman, Allan E. Siperstein, and Orlo H. Clark
Vascular Endothelial Growth Factor Expression Is Higher in Differentiated Thyroid Cancer than in Normal or Benign Thyroid
J Clin Endocrinol Metab 1997 82: 3741-3747. [Abstract] [Full Text]  

Kutluk Oktay, David Briggs, and Roger G. Gosden
Ontogeny of Follicle-Stimulating Hormone Receptor Gene Expression in Isolated Human Ovarian Follicles
J Clin Endocrinol Metab 1997 82: 3748-3751. [Abstract] [Full Text]  

A. Gardas, A. Lewartowska, B. J. Sutton, Z. Pasieka, A. M. McGregor, and J. P. Banga
Human Thyroid Peroxidase (TPO) Isoforms, TPO-1 and TPO-2: Analysis of Protein Expression in Graves’ Thyroid Tissue
J Clin Endocrinol Metab 1997 82: 3752-3757. [Abstract] [Full Text]  

A. Emptoz-Bonneton, J. C. Crave, H. Lejeune, C. Brébant, and M. Pugeat
Corticosteroid-Binding Globulin Synthesis Regulation by Cytokines and Glucocorticoids in Human Hepatoblastoma-Derived (HepG2) Cells
J Clin Endocrinol Metab 1997 82: 3758-3762. [Abstract] [Full Text]  

Steven W. Lockley, Debra J. Skene, Josephine Arendt, Homayoun Tabandeh, Alan C. Bird, and Remy Defrance
Relationship between Melatonin Rhythms and Visual Loss in the Blind
J Clin Endocrinol Metab 1997 82: 3763-3770. [Abstract] [Full Text]  

Philippe Caron, Louis Buscail, Albert Beckers, Jean-Pierre Estève, Ahmed Igout, Georges Hennen, and Christiane Susini
Expression of Somatostatin Receptor SST4 in Human Placenta and Absence of Octreotide Effect on Human Placental Growth Hormone Concentration during Pregnancy
J Clin Endocrinol Metab 1997 82: 3771-3776. [Abstract] [Full Text]  

Thein G. Tut, Farid J. Ghadessy, M. A. Trifiro, L. Pinsky, and E. L. Yong
Long Polyglutamine Tracts in the Androgen Receptor Are Associated with Reduced Trans-Activation, Impaired Sperm Production, and Male Infertility
J Clin Endocrinol Metab 1997 82: 3777-3782. [Abstract] [Full Text]  

Hana Rosolova, Otto Mayer, Jr., and Gerald Reaven
Effect of Variations in Plasma Magnesium Concentration on Resistance to Insulin-Mediated Glucose Disposal in Nondiabetic Subjects
J Clin Endocrinol Metab 1997 82: 3783-3785. [Abstract] [Full Text]  

Jean-Louis Vigne, James T. Murai, Bradley W. Arbogast, Weiping Jia, Susan J. Fisher, and Robert N. Taylor
Elevated Nonesterified Fatty Acid Concentrations in Severe Preeclampsia Shift the Isoelectric Characteristics of Plasma Albumin
J Clin Endocrinol Metab 1997 82: 3786-3792. [Abstract] [Full Text]  

Ramzi R. Hajjar, Fran E. Kaiser, and John E. Morley
Outcomes of Long-Term Testosterone Replacement in Older Hypogonadal Males: A Retrospective Analysis
J Clin Endocrinol Metab 1997 82: 3793-3796. [Abstract] [Full Text]  

Alessandro Peri, Guido Fantoni, Simone Granchi, Gabriella B. Vannelli, Tullio Barni, Sandra Amerini, Cinzia Pupilli, Guido Barbagli, Gianni Forti, Mario Serio, and Mario Maggi
Gene Expression of Endothelin-1, Endothelin-Converting Enzyme-1, and Endothelin Receptors in Human Epididymis
J Clin Endocrinol Metab 1997 82: 3797-3806. [Abstract] [Full Text]  

A. Biason-Lauber, E. Leiberman, and M. Zachmann
A Single Amino Acid Substitution in the Putative Redox Partner-Binding Site of P450c17 as Cause of Isolated 17,20-Lyase Deficiency
J Clin Endocrinol Metab 1997 82: 3807-3812. [Abstract] [Full Text]  

Tamar Amit, Tal Bergman, Florence Dastot, Moussa B. H. Youdim, Serge Amselem, and Ze’ev Hochberg
A Membrane-Fixed, Truncated Isoform of the Human Growth Hormone Receptor
J Clin Endocrinol Metab 1997 82: 3813-3817. [Abstract] [Full Text]  

Richard S. McIntosh, M. Suhail Asghar, E. Helen Kemp, Philip F. Watson, Andrzej Gardas, J. Paul Banga, and Anthony P. Weetman
Analysis of Immunoglobulin G{kappa} Antithyroid Peroxidase Antibodies from Different Tissues in Hashimoto’s Thyroiditis
J Clin Endocrinol Metab 1997 82: 3818-3825. [Abstract] [Full Text]  

Jun Nakae, Shuji Abe, Toshihiro Tajima, Nozomi Shinohara, Mari Murashita, Yutaka Igarashi, Satoshi Kusuda, Junzou Suzuki, and Kenji Fujieda
Three Novel Mutations and a De Novo Deletion Mutation of the DAX-1 Gene in Patients with X-Linked Adrenal Hypoplasia Congenita
J Clin Endocrinol Metab 1997 82: 3835-3841. [Abstract] [Full Text]  

Kazumi Iino, Hironobu Sasano, Yutaka Oki, Noriaki Andoh, Ryong-Woon Shin, Tetsuyuki Kitamoto, Kazuhito Totsune, Kazuhiro Takahashi, Hiroyoshi Suzuki, Hiroshi Nagura, and Teruya Yoshimi
Urocortin Expression in Human Pituitary Gland and Pituitary Adenoma
J Clin Endocrinol Metab 1997 82: 3842-3850. [Abstract] [Full Text]  

T. Z. Thomas, H. Wang, P. Niclasen, M. K. O’Bryan, L. W. Evans, N. P. Groome, J. Pedersen, and G. P. Risbridger
Expression and Localization of Activin Subunits and Follistatins in Tissues from Men with High Grade Prostate Cancer
J Clin Endocrinol Metab 1997 82: 3851-3858. [Abstract] [Full Text]  

Gen Hirasawa, Hironobu Sasano, Ken-ichi Takahashi, Kouhei Fukushima, Takashi Suzuki, Nobuo Hiwatashi, Takayosi Toyota, Zygmunt S. Krozowski, and Hiroshi Nagura
Colocalization of 11ß-Hydroxysteroid Dehydrogenase Type II and Mineralocorticoid Receptor in Human Epithelia
J Clin Endocrinol Metab 1997 82: 3859-3863. [Abstract] [Full Text]  

Graeme Eisenhofer, Anders Åneman, Peter Friberg, Douglas Hooper, Lars Fåndriks, Hans Lonroth, Béla Hunyady, and Eva Mezey
Substantial Production of Dopamine in the Human Gastrointestinal Tract
J Clin Endocrinol Metab 1997 82: 3864-3871. [Abstract] [Full Text]  

Nabil Moghrabi, Judith R. Head, and Stefan Andersson
Cell Type-Specific Expression of 17ß-Hydroxysteroid Dehydrogenase Type 2 in Human Placenta and Fetal Liver
J Clin Endocrinol Metab 1997 82: 3872-3878. [Abstract] [Full Text]  

H.-P. Holzapfel, P. Wonerow, W. von Petrykowski, M. Henschen, W. A. Scherbaum, and R. Paschke
Sporadic Congenital Hyperthyroidism due to a Spontaneous Germline Mutation in the Thyrotropin Receptor Gene
J Clin Endocrinol Metab 1997 82: 3879-3884. [Abstract] [Full Text]  

Dagmar Führer, Hans-Peter Holzapfel, Peter Wonerow, Werner A. Scherbaum, and Ralf Paschke
Somatic Mutations in the Thyrotropin Receptor Gene and Not in the Gs{alpha} Protein Gene in 31 Toxic Thyroid Nodules
J Clin Endocrinol Metab 1997 82: 3885-3891. [Abstract] [Full Text]  

José B. Mechica, Maria Odette R. Leite, Berenice B. Mendonca, Eliana S. T. Frazzatto, Aurélio Borelli, and Ana C. Latronico
COMMENTS: A Novel Nonsense Mutation in the First Zinc Finger of the Vitamin D Receptor Causing Hereditary 1,25-Dihydroxyvitamin D3-Resistant Rickets
J Clin Endocrinol Metab 1997 82: 3892-3894. [Abstract] [Full Text]  

Jerzy W. Kolaczynski, Barry J. Goldstein, and Robert V. Considine
COMMENTS: Dexamethasone, OB Gene, and Leptin in Humans; Effect of Exogenous Hyperinsulinemia
J Clin Endocrinol Metab 1997 82: 3895-3897. [Abstract] [Full Text]  

Rapid Communications:

C. R. Parker, Jr., R. L. Mixon, R. M. Brissie, and W. E. Grizzle
Aging Alters Zonation in the Adrenal Cortex of Men
J Clin Endocrinol Metab 1997 82: 3898-3901. [Abstract] [Full Text]  

Oliver Gimm, Debbie J. Marsh, Scott D. Andrew, Andrea Frilling, Patricia L. M. Dahia, Lois M. Mulligan, Jeffrey D. Zajac, Bruce G. Robinson, and Charis Eng
Germline Dinucleotide Mutation in Codon 883 of the RETProto-Oncogene in Multiple Endocrine Neoplasia Type 2B Without Codon 918 Mutation
J Clin Endocrinol Metab 1997 82: 3902-3904. [Abstract] [Full Text]  

Letters to the Editor:

Michael Weissel
Mild Clinical Expression of Myasthenia Gravis Associated with Autoimmune Thyroid Disease
J Clin Endocrinol Metab 1997 82: 3905. [Full Text]  

Michele Marinó, Giuseppe Barbesino, Luca Manetti, Luca Chiovato, Roberta Ricciardi, Bruno Rossi, Alberto Muratorio, Stefano Mariotti, Lewis E. Braverman, and Aldo Pinchera
Mild Clinical Expression of Myasthenia Gravis Associated with Autoimmune Thyroid Disease—Authors’ Response
J Clin Endocrinol Metab 1997 82: 3905a-3906. [Full Text]  

Zubair Baloch and Virginia A. Livolsi
Detection of an Activating Mutation of the Thyrotropin Receptor in a Case of an Autonomously Hyperfunctioning Thyroid Insular Carcinoma
J Clin Endocrinol Metab 1997 82: 3906. [Full Text]  

D. Russo, S. Filetti, G. Grasso, Osp. S. Pietro e Gravina, S. Tumino, and A. Belfiore
Detection of an Activating Mutation of the Thyrotropin Receptor in a Case of an Autonomously Hyperfunctioning Thyroid Insular Carcinoma—Authors’ Response
J Clin Endocrinol Metab 1997 82: 3906a-3908. [Full Text]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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