help button home button Endocrine Society JCEM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a related Letter to the Editor
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Weyer, C.
Right arrow Articles by Tataranni, P. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Weyer, C.
Right arrow Articles by Tataranni, P. A.
Right arrowPubmed/NCBI databases
*Substance via MeSH
Medline Plus Health Information
*Diabetes
*Nutrition
*Obesity
The Journal of Clinical Endocrinology & Metabolism Vol. 86, No. 5 1930-1935
Copyright © 2001 by The Endocrine Society

Original Studies

Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia

Christian Weyer, Tohru Funahashi, Sachiyo Tanaka, Kikuko Hotta, Yuji Matsuzawa, Richard E. Pratley and P. Antonio Tataranni

Clinical Diabetes and Nutrition Section (C.W., R.E.P., P.A.T.), National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85016; and Department of Internal Medicine and Molecular Science (T.F., S.T., K.H., Y.M.), Graduate School of Medicine, Osaka University, Osaka, Japan

Address all correspondence and requests for reprints to: Christian Weyer, M.D., Clinical Diabetes and Nutrition Section, National Institutes of Health, 4212 North 16th Street, Room 5-41, Phoenix, Arizona 85016. E-mail: cweyer{at}phx.niddk.nih.gov

Plasma concentrations of adiponectin, a novel adipose-specific protein with putative antiatherogenic and antiinflammatory effects, were found to be decreased in Japanese individuals with obesity, type 2 diabetes, and cardiovascular disease, conditions commonly associated with insulin resistance and hyperinsulinemia.

To further characterize the relationship between adiponectinemia and adiposity, insulin sensitivity, insulinemia, and glucose tolerance, we measured plasma adiponectin concentrations, body composition (dual-energy x-ray absorptiometry), insulin sensitivity (M, hyperinsulinemic clamp), and glucose tolerance (75-g oral glucose tolerance test) in 23 Caucasians and 121 Pima Indians, a population with a high propensity for obesity and type 2 diabetes.

Plasma adiponectin concentration was negatively correlated with percent body fat (r = -0.43), waist-to-thigh ratio (r = -0.46), fasting plasma insulin concentration (r = -0.63), and 2-h glucose concentration (r = -0.38), and positively correlated with M (r = 0.59) (all P < 0.001); all relations were evident in both ethnic groups. In a multivariate analysis, fasting plasma insulin concentration, M, and waist-to-thigh ratio, but not percent body fat or 2-h glucose concentration, were significant independent determinates of adiponectinemia, explaining 47% of the variance (r2 = 0.47). Differences in adiponectinemia between Pima Indians and Caucasians (7.2 ± 2.6 vs. 10.2 ± 4.3 µg/ml, P < 0.0001) and between Pima Indians with normal, impaired, and diabetic glucose tolerance (7.5 ± 2.7, 6.1 ± 2.0, 5.5 ± 1.6 µg/ml, P < 0.0001) remained significant after adjustment for adiposity, but not after additional adjustment for M or fasting insulin concentration.

These results confirm that obesity and type 2 diabetes are associated with low plasma adiponectin concentrations in different ethnic groups and indicate that the degree of hypoadiponectinemia is more closely related to the degree of insulin resistance and hyperinsulinemia than to the degree of adiposity and glucose intolerance.




This article has been cited by other articles:


Home page
 J Antimicrob ChemotherHome page
J. E. Mallewa, E. Wilkins, J. Vilar, M. Mallewa, D. Doran, D. Back, and M. Pirmohamed
HIV-associated lipodystrophy: a review of underlying mechanisms and therapeutic options
J. Antimicrob. Chemother., October 1, 2008; 62(4): 648 - 660.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
G. Maiolino, M. Cesari, D. Sticchi, M. Zanchetta, L. Pedon, K. Antezza, A. C. Pessina, and G. P. Rossi
Plasma Adiponectin for Prediction of Cardiovascular Events and Mortality in High-Risk Patients
J. Clin. Endocrinol. Metab., September 1, 2008; 93(9): 3333 - 3340.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
P. Perez-Martinez, J. Lopez-Miranda, C. Cruz-Teno, J. Delgado-Lista, Y. Jimenez-Gomez, J. M. Fernandez, M. J. Gomez, C. Marin, F. Perez-Jimenez, and J. M. Ordovas
Adiponectin Gene Variants Are Associated with Insulin Sensitivity in Response to Dietary Fat Consumption in Caucasian Men
J. Nutr., September 1, 2008; 138(9): 1609 - 1614.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
S. J. Peterson, G. Drummond, D. H. Kim, M. Li, A. L. Kruger, S. Ikehara, and N. G. Abraham
L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice
J. Lipid Res., August 1, 2008; 49(8): 1658 - 1669.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
H. Leth, K. K. Andersen, J. Frystyk, L. Tarnow, P. Rossing, H.-H. Parving, and A. Flyvbjerg
Elevated Levels of High-Molecular-Weight Adiponectin in Type 1 Diabetes
J. Clin. Endocrinol. Metab., August 1, 2008; 93(8): 3186 - 3191.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
T. M. Barber, M. Hazell, C. Christodoulides, S. J. Golding, C. Alvey, K. Burling, A. Vidal-Puig, N. P. Groome, J. A. H. Wass, S. Franks, et al.
Serum Levels of Retinol-Binding Protein 4 and Adiponectin in Women with Polycystic Ovary Syndrome: Associations with Visceral Fat But No Evidence for Fat Mass-Independent Effects on Pathogenesis in This Condition
J. Clin. Endocrinol. Metab., July 1, 2008; 93(7): 2859 - 2865.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
H. Pinar, S. Basu, K. Hotmire, L. Laffineuse, L. Presley, M. Carpenter, P. M. Catalano, and S. Hauguel-de Mouzon
High Molecular Mass Multimer Complexes and Vascular Expression Contribute to High Adiponectin in the Fetus
J. Clin. Endocrinol. Metab., July 1, 2008; 93(7): 2885 - 2890.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
L. M Ritland, D L. Alekel, O. A Matvienko, K. B Hanson, J. W Stewart, L. N Hanson, M. B Reddy, M. D Van Loan, and U. Genschel
Centrally located body fat is related to appetitive hormones in healthy postmenopausal women.
Eur. J. Endocrinol., June 1, 2008; 158(6): 889 - 897.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Pathol.Home page
R Olufadi and C D Byrne
Clinical and laboratory diagnosis of the metabolic syndrome
J. Clin. Pathol., June 1, 2008; 61(6): 697 - 706.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
M. Li, D. H. Kim, P. L. Tsenovoy, S. J. Peterson, R. Rezzani, L. F. Rodella, W. S. Aronow, S. Ikehara, and N. G. Abraham
Treatment of Obese Diabetic Mice With a Heme Oxygenase Inducer Reduces Visceral and Subcutaneous Adiposity, Increases Adiponectin Levels, and Improves Insulin Sensitivity and Glucose Tolerance
Diabetes, June 1, 2008; 57(6): 1526 - 1535.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
S. E. Recabarren, R. Smith, R. Rios, M. Maliqueo, B. Echiburu, E. Codner, F. Cassorla, P. Rojas, and T. Sir-Petermann
Metabolic Profile in Sons of Women with Polycystic Ovary Syndrome
J. Clin. Endocrinol. Metab., May 1, 2008; 93(5): 1820 - 1826.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
C Joaquin, E Aguilera, M L Granada, M C Pastor, I Salinas, N Alonso, and A Sanmarti
Effects of GH treatment in GH-deficient adults on adiponectin, leptin and pregnancy-associated plasma protein-A.
Eur. J. Endocrinol., April 1, 2008; 158(4): 483 - 490.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
M. Kyriakakou, A. Malamitsi-Puchner, H. Militsi, T. Boutsikou, A. Margeli, D. Hassiakos, C. Kanaka-Gantenbein, I. Papassotiriou, and G. Mastorakos
Leptin and adiponectin concentrations in intrauterine growth restricted and appropriate for gestational age fetuses, neonates, and their mothers
Eur. J. Endocrinol., March 1, 2008; 158(3): 343 - 348.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
Y. Tabara, H. Osawa, R. Kawamoto, R. Tachibana-Iimori, M. Yamamoto, J. Nakura, T. Miki, H. Makino, and K. Kohara
Reduced High-Molecular-Weight Adiponectin and Elevated High-Sensitivity C-Reactive Protein Are Synergistic Risk Factors for Metabolic Syndrome in a Large-Scale Middle-Aged to Elderly Population: the Shimanami Health Promoting Program Study
J. Clin. Endocrinol. Metab., March 1, 2008; 93(3): 715 - 722.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart J SupplHome page
R. W. Nesto and K. Mackie
Endocannabinoid system and its implications for obesity and cardiometabolic risk
Eur. Heart J. Suppl., March 1, 2008; 10(suppl_B): B34 - B41.
[Abstract] [Full Text] [PDF]

Home page
 The Diabetes EducatorHome page
P. Hollander
Cardiometabolic Risk Factors and Visceral Adipose Tissue
The Diabetes Educator, March 1, 2008; 34(Supplement_2): 37S - 41S.
[Abstract] [Full Text] [PDF]

Home page
 The Diabetes EducatorHome page
S. T. Boyd
Management Through Risk Factor Modification
The Diabetes Educator, March 1, 2008; 34(Supplement_2): 42S - 48S.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
M. K. Ohman, Y. Shen, C. I. Obimba, A. P. Wright, M. Warnock, D. A. Lawrence, and D. T. Eitzman
Visceral Adipose Tissue Inflammation Accelerates Atherosclerosis in Apolipoprotein E-Deficient Mice
Circulation, February 12, 2008; 117(6): 798 - 805.
[Abstract] [Full Text] [PDF]

Home page
 Chronic Respiratory DiseaseHome page
M. Poulain, M. Doucet, V. Drapeau, G. Fournier, A. Tremblay, P. Poirier, and F. Maltais
Metabolic and inflammatory profile in obese patients with chronic obstructive pulmonary disease
Chronic Respiratory Disease, February 1, 2008; 5(1): 35 - 41.
[Abstract] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
J. Koska, N. Stefan, P. A Permana, C. Weyer, M. Sonoda, C. Bogardus, S. R Smith, D. R Joanisse, T. Funahashi, J. Krakoff, et al.
Increased fat accumulation in liver may link insulin resistance with subcutaneous abdominal adipocyte enlargement, visceral adiposity, and hypoadiponectinemia in obese individuals
Am. J. Clinical Nutrition, February 1, 2008; 87(2): 295 - 302.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
E. L Madsen, A. Rissanen, J. M Bruun, K. Skogstrand, S. Tonstad, D. M Hougaard, and B. Richelsen
Weight loss larger than 10% is needed for general improvement of levels of circulating adiponectin and markers of inflammation in obese subjects: a 3-year weight loss study
Eur. J. Endocrinol., February 1, 2008; 158(2): 179 - 187.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
M. E. Spurlock and N. K. Gabler
The Development of Porcine Models of Obesity and the Metabolic Syndrome
J. Nutr., February 1, 2008; 138(2): 397 - 402.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
S. H. S. Santos, L. R. Fernandes, E. G. Mario, A. V. M. Ferreira, L. C. J. Porto, J. I. Alvarez-Leite, L. M. Botion, M. Bader, N. Alenina, and R. A. S. Santos
Mas Deficiency in FVB/N Mice Produces Marked Changes in Lipid and Glycemic Metabolism
Diabetes, February 1, 2008; 57(2): 340 - 347.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
A. M.J. Wassink, Y. van der Graaf, J. K. Olijhoek, F. L.J. Visseren, and for the SMART Study Group
Metabolic syndrome and the risk of new vascular events and all-cause mortality in patients with coronary artery disease, cerebrovascular disease, peripheral arterial disease or abdominal aortic aneurysm
Eur. Heart J., January 2, 2008; 29(2): 213 - 223.
[Abstract] [Full Text] [PDF]

Home page
 ERRHome page
I. A. Harsch
Metabolic disturbances in patients with obstructive sleep apnoea syndrome
Eur. Respir. Rev., December 1, 2007; 16(106): 196 - 202.
[Abstract] [Full Text] [PDF]

Home page
 J. Gerontol. A Biol. Sci. Med. Sci.Home page
S. E. Yeo, N. P. Hays, R. A. Dennis, P. M. Kortebein, D. H. Sullivan, W. J. Evans, and R. H. Coker
Fat Distribution and Glucose Metabolism in Older, Obese Men and Women
J. Gerontol. A Biol. Sci. Med. Sci., December 1, 2007; 62(12): 1393 - 1401.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
T. Sir-Petermann, M. Maliqueo, E. Codner, B. Echiburu, N. Crisosto, V. Perez, F. Perez-Bravo, and F. Cassorla
Early Metabolic Derangements in Daughters of Women with Polycystic Ovary Syndrome
J. Clin. Endocrinol. Metab., December 1, 2007; 92(12): 4637 - 4642.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Chem.Home page
M. K. Sinha, T. Songer, Q. Xiao, J. H. Sloan, J. Wang, S. Ji, W. E. Alborn, R. A. Davis, M. M. Swarbrick, K. L. Stanhope, et al.
Analytical Validation and Biological Evaluation of a High Molecular-Weight Adiponectin ELISA
Clin. Chem., December 1, 2007; 53(12): 2144 - 2151.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
L. Hojbjerre, M. Rosenzweig, F. Dela, J. M Bruun, and B. Stallknecht
Acute exercise increases adipose tissue interstitial adiponectin concentration in healthy overweight and lean subjects
Eur. J. Endocrinol., November 1, 2007; 157(5): 613 - 623.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
M. H Rokling-Andersen, J. E Reseland, M. B Veierod, S. A Anderssen, D. R Jacobs Jr, P. Urdal, J.-O. Jansson, and C. A Drevon
Effects of long-term exercise and diet intervention on plasma adipokine concentrations
Am. J. Clinical Nutrition, November 1, 2007; 86(5): 1293 - 1301.
[Abstract] [Full Text] [PDF]

Home page
 Diabetes CareHome page
T. W.K. Ng, G. F. Watts, P. H. R. Barrett, K.-A. Rye, and D. C. Chan
Effect of Weight Loss on LDL and HDL Kinetics in the Metabolic Syndrome: Associations with changes in plasma retinol-binding protein-4 and adiponectin levels
Diabetes Care, November 1, 2007; 30(11): 2945 - 2950.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
A. Galler, G. Gelbrich, J. Kratzsch, N. Noack, T. Kapellen, and W. Kiess
Elevated serum levels of adiponectin in children, adolescents and young adults with type 1 diabetes and the impact of age, gender, body mass index and metabolic control: a longitudinal study
Eur. J. Endocrinol., October 1, 2007; 157(4): 481 - 489.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
K. A. Varady, D. J. Roohk, Y. C. Loe, B. K. McEvoy-Hein, and M. K. Hellerstein
Effects of modified alternate-day fasting regimens on adipocyte size, triglyceride metabolism, and plasma adiponectin levels in mice
J. Lipid Res., October 1, 2007; 48(10): 2212 - 2219.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
S. Murosaki, T. R. Lee, K. Muroyama, E. S. Shin, S. Y. Cho, Y. Yamamoto, and S. J. Lee
A Combination of Caffeine, Arginine, Soy Isoflavones, and L-Carnitine Enhances Both Lipolysis and Fatty Acid Oxidation in 3T3-L1 and HepG2 Cells in Vitro and in KK Mice in Vivo
J. Nutr., October 1, 2007; 137(10): 2252 - 2257.
[Abstract] [Full Text] [PDF]

Home page
 Am J EpidemiolHome page
D. M. Maahs, L. G. Ogden, J. K. Snell-Bergeon, G. L. Kinney, R. P. Wadwa, J. E. Hokanson, D. Dabelea, A. Kretowski, R. H. Eckel, and M. Rewers
Determinants of Serum Adiponectin in Persons with and without Type 1 Diabetes
Am. J. Epidemiol., September 15, 2007; 166(6): 731 - 740.
[Abstract] [Full Text] [PDF]

Home page
 Endocr Relat CancerHome page
Y.-F. Tian, C.-H. Chu, M.-H. Wu, C.-L. Chang, T. Yang, Y.-C. Chou, G.-C. Hsu, C.-P. Yu, J.-C. Yu, and C.-A. Sun
Anthropometric measures, plasma adiponectin, and breast cancer risk
Endocr. Relat. Cancer, September 1, 2007; 14(3): 669 - 677.
[Abstract] [Full Text] [PDF]

Home page
 Endocr Relat CancerHome page
L. Cong, J. Gasser, J. Zhao, B. Yang, F. Li, and A. Z Zhao
Human adiponectin inhibits cell growth and induces apoptosis in human endometrial carcinoma cells, HEC-1-A and RL95 2
Endocr. Relat. Cancer, September 1, 2007; 14(3): 713 - 720.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
M. Bullo, M. R Peeraully, P. Trayhurn, J Folch, and J. Salas-Salvado
Circulating nerve growth factor levels in relation to obesity and the metabolic syndrome in women
Eur. J. Endocrinol., September 1, 2007; 157(3): 303 - 310.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
D. Barb, C. J Williams, A. K Neuwirth, and C. S Mantzoros
Adiponectin in relation to malignancies: a review of existing basic research and clinical evidence
Am. J. Clinical Nutrition, September 1, 2007; 86(3): 858S - 866S.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
W.-S. Yang, Y.-C. Yang, C.-L. Chen, I-L. Wu, J.-Y. Lu, F.-H. Lu, T.-Y. Tai, and C.-J. Chang
Adiponectin SNP276 is associated with obesity, the metabolic syndrome, and diabetes in the elderly
Am. J. Clinical Nutrition, August 1, 2007; 86(2): 509 - 513.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
A. E Schutte, H. W Huisman, R. Schutte, L. Malan, J. M van Rooyen, N. T Malan, and P. E H Schwarz
Differences and similarities regarding adiponectin investigated in African and Caucasian women
Eur. J. Endocrinol., August 1, 2007; 157(2): 181 - 188.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
A Klamer, K Skogstrand, D M Hougaard, B Norgaard-Petersen, A Juul, and G Greisen
Adiponectin levels measured in dried blood spot samples from neonates born small and appropriate for gestational age
Eur. J. Endocrinol., August 1, 2007; 157(2): 189 - 194.
[Abstract] [Full Text] [PDF]

Home page
 J EndocrinolHome page
G. Yuan, X. Chen, Q. Ma, J. Qiao, R. Li, X. Li, S. Li, J. Tang, L. Zhou, H. Song, et al.
C-reactive protein inhibits adiponectin gene expression and secretion in 3T3-L1 adipocytes
J. Endocrinol., August 1, 2007; 194(2): 275 - 281.
[Abstract] [Full Text] [PDF]

Home page
 J EndocrinolHome page
T. Josephs, H. Waugh, I. Kokay, D. Grattan, and M. Thompson
Fasting-induced adipose factor identified as a key adipokine that is up-regulated in white adipose tissue during pregnancy and lactation in the rat
J. Endocrinol., August 1, 2007; 194(2): 305 - 312.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
L. J. Moran, M. Noakes, P. M. Clifton, G. A. Wittert, D. P. Belobrajdic, and R. J. Norman
C-Reactive Protein before and after Weight Loss in Overweight Women with and without Polycystic Ovary Syndrome
J. Clin. Endocrinol. Metab., August 1, 2007; 92(8): 2944 - 2951.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
M. Cesari, K. Narkiewicz, R. De Toni, E. Aldighieri, C. J. Williams, and G. P. Rossi
Heritability of Plasma Adiponectin Levels and Body Mass Index in Twins
J. Clin. Endocrinol. Metab., August 1, 2007; 92(8): 3082 - 3088.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
A. J. G. Hanley, D. Bowden, L. E. Wagenknecht, A. Balasubramanyam, C. Langfeld, M. F. Saad, J. I. Rotter, X. Guo, Y.-D. I. Chen, M. Bryer-Ash, et al.
Associations of Adiponectin with Body Fat Distribution and Insulin Sensitivity in Nondiabetic Hispanics and African-Americans
J. Clin. Endocrinol. Metab., July 1, 2007; 92(7): 2665 - 2671.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
T. Sir-Petermann, B. Echiburu, M M. Maliqueo, N. Crisosto, F. Sanchez, C. Hitschfeld, M. Carcamo, P. Amigo, and F. Perez-Bravo
Serum adiponectin and lipid concentrations in pregnant women with polycystic ovary syndrome
Hum. Reprod., July 1, 2007; 22(7): 1830 - 1836.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
J. Jurimae and T. Jurimae
Plasma adiponectin concentration in healthy pre- and postmenopausal women: relationship with body composition, bone mineral, and metabolic variables
Am J Physiol Endocrinol Metab, July 1, 2007; 293(1): E42 - E47.
[Abstract] [Full Text] [PDF]

Home page
 Diabetes CareHome page
J.A. Paniagua, A. G. de la Sacristana, I. Romero, A. Vidal-Puig, J.M. Latre, E. Sanchez, P. Perez-Martinez, J. Lopez-Miranda, and F. Perez-Jimenez
Monounsaturated Fat-Rich Diet Prevents Central Body Fat Distribution and Decreases Postprandial Adiponectin Expression Induced by a Carbohydrate-Rich Diet in Insulin-Resistant Subjects
Diabetes Care, July 1, 2007; 30(7): 1717 - 1723.
[Abstract] [Full Text] [PDF]

Home page
 Diabetes CareHome page
L. A. Barbour, C. E. McCurdy, T. L. Hernandez, J. P. Kirwan, P. M. Catalano, and J. E. Friedman
Cellular Mechanisms for Insulin Resistance in Normal Pregnancy and Gestational Diabetes
Diabetes Care, July 1, 2007; 30(Supplement_2): S112 - S119.
[Full Text] [PDF]

Home page
 J. Am. Coll. Nutr.Home page
S. Santosa, I. Demonty, A. H. Lichtenstein, K. Cianflone, and P. J.H. Jones
An Investigation of Hormone and Lipid Associations after Weight Loss in Women
J. Am. Coll. Nutr., June 1, 2007; 26(3): 250 - 258.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
R. K. Stoving, J.-W. Chen, D. Glintborg, K. Brixen, A. Flyvbjerg, K. Horder, and J. Frystyk
Bioactive Insulin-Like Growth Factor (IGF) I and IGF-Binding Protein-1 in Anorexia Nervosa
J. Clin. Endocrinol. Metab., June 1, 2007; 92(6): 2323 - 2329.
[Abstract] [Full Text] [PDF]

Home page
 Diabetes CareHome page
N. R. Poa and P. F. Edgar
Insulin Resistance Is Associated With Hypercortisolemia in Polynesian Patients Treated With Antipsychotic Medication
Diabetes Care, June 1, 2007; 30(6): 1425 - 1429.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
C. M. de Souza Batista, R.-Z. Yang, M.-J. Lee, N. M. Glynn, D.-Z. Yu, J. Pray, K. Ndubuizu, S. Patil, A. Schwartz, M. Kligman, et al.
Omentin Plasma Levels and Gene Expression Are Decreased in Obesity
Diabetes, June 1, 2007; 56(6): 1655 - 1661.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
L. Qi, A. Doria, E. Giorgi, and F. B. Hu
Variations in Adiponectin Receptor Genes and Susceptibility to Type 2 Diabetes in Women: A Tagging-Single Nucleotide Polymorphism Haplotype Analysis
Diabetes, June 1, 2007; 56(6): 1586 - 1591.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
W.-S. Chow, B. M.Y. Cheung, A. W.K. Tso, A. Xu, N. M.S. Wat, C. H.Y. Fong, L. H.Y. Ong, S. Tam, K. C.B. Tan, E. D. Janus, et al.
Hypoadiponectinemia as a Predictor for the Development of Hypertension: A 5-Year Prospective Study
Hypertension, June 1, 2007; 49(6): 1455 - 1461.
[Abstract] [Full Text] [PDF]

Home page