Supplemental Data

Supplemental Data

Files in this Data Supplement:

• Appendix Figure S1 - Random-effects meta-analysis of insulin sensitizers vs. placebo for the treatment of hirsutism. Vertical lines represent no treatment effect. Squares and horizontal lines represent the point estimates and associated CI for each comparison, expressed as Ferriman-Gallwey scores. The diamond represents the random-effects pooled weighted mean difference (WMD) for insulin sensitizers vs. placebo, with the center representing the point estimate and the width representing the associated CI.
• Appendix Figure S2 - Random-effects meta-analysis of insulin sensitizers vs. OCPs for the treatment of hirsutism. Vertical lines represent no treatment effect. Squares and horizontal lines represent the point estimates and associated CI for each comparison, expressed as Ferriman-Gallwey scores. The diamond represents the random-effects pooled weighted mean difference (WMD) for insulin sensitizers vs. OCPs, with the center representing the point estimate and the width representing the associated CI.
• Appendix Figure S3 - Random-effects meta-analysis of insulin sensitizers (metformin) vs. anti-androgens for the treatment of hirsutism. Vertical lines represent no treatment effect. Squares and horizontal lines represent the point estimates and associated CI for each comparison, expressed as Ferriman-Gallwey scores. The diamond represents the random-effects pooled weighted mean difference (WMD) for metformin vs. flutamide, with the center representing the point estimate and the width representing the associated CI.
• Appendix Figure S4 - Random-effects meta-analysis of insulin sensitizers (metformin) in combination with other treatments for the treatment of hirsutism. Vertical lines represent no treatment effect. Squares and horizontal lines represent the point estimates and associated CI for each comparison, expressed as Ferriman-Gallwey scores. The diamond represents the random-effects pooled weighted mean difference (WMD) with the center representing the point estimate and the width representing the associated CI. A - Metformin and flutamide vs. OCPs. B - Metformin and flutamide vs. flutamide. C – Metformin and flutamide vs. metformin.