| Patient |
Age (yr)/ sex |
Diagnosis |
Duration of alendronate treatment (yr) |
Other medications |
Incident fractures (yr on alendronate) |
Delayed/absent healing on alendronate (fracture site) |
Fracture healing yes/no (months off alendronate) |
|
| Group A |
|
|
|
|
|
|
|
| 1 |
55/F |
PO |
6 |
Ca, D |
Sacrum (6) |
NA |
No (12) |
| 2 |
76/F |
PO |
7 |
Ca, D |
Vertebra, rib (7) |
NA |
Yes (6) |
| 3 |
52/F |
POpen |
8 |
Ca, D |
Femoral shaft (8) |
4 months (femoral shaft) |
No (9) |
| 4 |
68/M |
IO |
8 |
Ca, D |
Bilateral femoral shaft (8) |
NA |
No (8) |
| Group B |
|
|
|
|
|
|
|
| 5 |
68/F |
PO |
3 |
E2, Ca, D |
Sacrum, ischium (3) |
3 months (ischium) |
Yes (8) |
| 6 |
70/F |
PO |
5 |
E2, Ca, D |
Pubic rami (3) |
2 yr (pubic rami) |
Yes (4) |
| 7 |
67/F |
POpen |
5 |
E2, Ca, D |
Bilateral femoral shaft (5) |
9 months (left femoral shaft) |
Yes (5) |
| Group C |
|
|
|
|
|
|
|
| 8 |
49/F |
GIO (asthma) |
3 |
Prednisone, Ca, D |
Proximal femur (1) |
2 yr (femur) |
No (8) |
| 9 |
64/F |
GIO (fibromyalgia) |
4 |
Prednisone, Ca, D |
Metatarsal, proximal femur (3) |
8 months (proximal femur) |
Yes (3) |
|
