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FIG. 2. Pattern of change over time for the TSH and FT4 serum values (mean ± SD) collected at six periods: before OH (time 0), and at d 20, 40, 60, 80, and 100 after successful OI. Left panels, Among all patients, a significant difference exists in the TSH and FT4 measures over time (one-way repeated-measures ANOVA for TSH and FT4, P < 0.001 and P = 0.005, respectively). Right panels, The pattern of change over time is different for TPO+ ( ) and TPO ( ) (two-way repeated-measures ANOVA for TSH and FT4, P = 0.010 and P = 0.020, respectively) patients. Conversion factor for FT4 (nanograms per liter picomoles per liter), 1.29. NS, Not significant.
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