HT SAT Prior goiter Usual Rare Prior AITD Usual No Prior URTI Infrequent Frequent Pain/tenderness Present, may be extreme Extreme Goiter at onset Yes Yes Thyrotoxicosis at onset Variable Yes, usually RAIU Low or normal or high Very low Free thyroxine index Variable Variable CRP/ESR Normal or elevated Elevated MCAB Usually strong positive Negative or weak Pathology Fibrosis, lymphocytes Giant cells, polymorphs Steroid response Yes or no Yes Risk of long-term hypothyroidism Yes Rare Treatment T4, acetaminophen, aspirin, NSAID steroids, thyroidectomy Acetaminophen, aspirin, NSAID, steroids

AITD, Autoimmune thyroid disease; MCAB, monoclonal antibody.

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