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The Journal of Clinical Endocrinology & Metabolism Vol. 85, No. 12 4921-4922
Copyright © 2000 by The Endocrine Society

Letters to the Editor

In Vivo Measurement of Renal 11ß-Hydroxysteroid Dehydrogenase Type 2 Activity

M. Quinkler, W. Oelkers and S. Diederich

Department of Endocrinology Universitätsklinikum Benjamin Franklin Freie Universität Berlin 12200 Berlin, Germany {hd2}To the editor:

Received June 6, 2000.

References

  1. Lovati E, Ferrari P, Dick B, et al. 1999 Molecular basis of human salt sensitivity: the role of the 11ß-hydroxysteroid dehydrogenase type 2. J Clin Endocrinol Metab. 84:3745–3749.[Abstract/Free Full Text]
  2. Ferrari P, Lovati E, Frey FJ. 2000 The role of the 11ß-hydroxysteroid dehydrogenase type 2 in human hypertension. J Hypertens. 18:241–248.[CrossRef][Medline]
  3. Brand E, Kato N, Chatelain N, et al. 1998 Structural analysis and evaluation of the 11ß-hydroxysteroid dehydrogenase (11ß-HSD-2) gene in human essential hypertension. J Hypertens. 16:1627–1633.[CrossRef][Medline]
  4. Connell JMC, Kenyon CJ, Ingram M, et al. 1996 Corticosteroids in essential hypertension: multiple candidate loci and phenotypic variation. Clin Exp Pharmacol Physiol. 23:369–374.[Medline]
  5. Ingram MC, Wallace AM, Collier A, Fraser R, Connell JMC. 1996 Sodium status, corticosteroid metabolism and blood pressure in normal human subjects and in a patient with abnormal salt appetite. Clin Exp Pharmacol Physiol. 23:375–378.[CrossRef][Medline]
  6. Iki K, Miyamori I, Hatakeyama H, et al. 1994 The activities of 5ß-reductase and 11ß-hydroxysteroid dehydrogenase in essential hypertension. Steroids. 59:656–660.[CrossRef][Medline]
  7. Soro A, Ingram MC, Tonolo G, Glorioso N, Fraser R. 1995 Evidence of coexisting changes in 11ß-hydroxysteroid dehydrogenase and 5ß-reductase activity in subjects with untreated essential hypertension. Hypertension. 25:67–70.[Abstract/Free Full Text]
  8. Vogt B, Dick B, N'Gankam V, Frey FJ, Frey BM. 1999 Reduced 11ß-hydroxysteroid dehydrogenase activity in patients with the nephrotic syndrome. J Clin Endocrinol Metab. 84:811–814.[Abstract/Free Full Text]
  9. Andrew R, Phillips DIW, Walker BR. 1998 Obesity and gender influence cortisol secretion and metabolism in man. J Clin Endocrinol Metab. 83:1806–1809.[Abstract/Free Full Text]
  10. Stewart PM, Boulton A, Kumar S, Clark PMS, Shackleton CHL. 1999 Cortisol metabolism in human obesity: impaired cortisone to cortisol conversion in subjects with central adiposity. J Clin Endocrinol Metab. 84:1022–1027.[Abstract/Free Full Text]
  11. Finken MJJ, Andrews RC, Andrew R, Walker BR. 1999 Cortisol metabolism in healthy young adults: sexual dimorphism in activities of A-ring reductases, but not 11ß-hydroxysteroid dehydrogenases. J Clin Endocrinol Metab. 84:3316–3321.[Abstract/Free Full Text]
  12. Palermo M, Cossu M, Shackleton CHL. 1998 Cure of apparent mineralocorticoid excess by kidney transplantation. N Engl J Med. 329:1787–1788.
  13. Best R, Walker BR. 1997 Additional value of measurement of urinary cortisone and unconjugated cortisol metabolites in assessing the activity of 11ß-hydroxysteroid dehydrogenase. Clin Endocrinol. 47:231–236.[CrossRef][Medline]
  14. Mantero F, Palermo M, Petrelli MD, Tedde R, Stewart PM, Shackleton CHL. 1996 Apparent mineralocorticoid excess: type I and type II. Steroids. 61:193–196.[CrossRef][Medline]
  15. Inglis GC, Ingram MC, Holloway CD, et al. 1999 Familial pattern of corticosteroids and their metabolism in adult human subjects—the Scottish adult twin study. J Clin Endocrinol Metab. 84:4132–4137.[Abstract/Free Full Text]




This Article
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