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Journal of Clinical Endocrinology & Metabolism, Vol 80, 1956-1959, Copyright © 1995 by Endocrine Society


ARTICLES

Islet amyloid polypeptide in pancreatic tissue of children with persistent hyperinsulinemic hypoglycemia caused by primary islet hyperplasia and nesidioblastosis

KI Rother, JA Carney, M Couce, J Charlesworth and PC Butler
Endocrine Research Unit, Mayo Clinic, Rochester, Minnesota 55905, USA.

Islet amyloid is a recognized characteristic finding in insulinoma and secondary islet hyperplasia resulting from severe insulin resistance. Little information is available about the presence of islet amyloid in primary islet hyperplasia (nesidioblastosis) of childhood. Here we report that islet amyloid was not present in 12 children with primary islet hyperplasia associated with hyperinsulinemic hypoglycemia.





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Copyright © 1995 by The Endocrine Society