help button home button Endocrine Society JCEM JCEM Call for Nominations for EIC
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a related Letter to the Editor
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mulheron, G. W.
Right arrow Articles by Schomberg, D. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mulheron, G. W.
Right arrow Articles by Schomberg, D. W.

Journal of Clinical Endocrinology & Metabolism, Vol 74, 458-460, Copyright © 1992 by Endocrine Society

ARTICLES

Human granulosa-luteal and cumulus cells express transforming growth factors-beta type 1 and type 2 mRNA

GW Mulheron, NL Bossert, JA Lapp, DK Walmer and DW Schomberg
Department of Obstetrics/Gynecology, Duke University Medical Center, Durham, NC 27710.

Human granulosa-luteal cells and cumulus cells obtained from women undergoing in vitro fertilization and embryo transfer (IVF-ET) were examined for the presence of TGF-beta 1 and TGF-beta 2 mRNA by reverse transcription-polymerase chain reaction (RT-PCR) analysis. RT-PCR analysis revealed that both follicle cell types express mRNA for both TGF-beta subtypes. Verification of RT-PCR products was done by restriction enzyme digestion analysis. These results suggest a role(s) for TGF-beta 1 and TGF-beta 2 in the development of human granulosa- luteal cells and the oocyte-cumulus cell complex.


This article has been cited by other articles:


Home page
 Mol Hum ReprodHome page
C. Osterlund and G. Fried
TGF{beta} receptor types I and II and the substrate proteins Smad 2 and 3 are present in human oocytes
Mol. Hum. Reprod., June 1, 2000; 6(6): 498 - 503.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
J. Qu, P. A. Godin, M. Nisolle, and J. Donnez
Expression of receptors for insulin-like growth factor-I and transforming growth factor-{beta} in human follicles
Mol. Hum. Reprod., February 1, 2000; 6(2): 137 - 145.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
B. Bieser,, M. Stojkovic,, E. Wolf,, H. Meyer,, and R. Einspanier
Growth Factors and Components for Extracellular Proteolysis Are Differentially Expressed during In Vitro Maturation of Bovine Cumulus-Oocyte Complexes
Biol Reprod, October 1, 1998; 59(4): 801 - 806.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1992 by The Endocrine Society