help button home button Endocrine Society JCEM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS

Journal of Clinical Endocrinology & Metabolism Vol. 71, No. 2 505-508
doi:10.1210/jcem-71-2-505
Copyright © 1990 by the Endocrine Society.
This Article
Right arrow Full Text (PDF)
Right arrow Submit a related Letter to the Editor
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by LURIE, S. N.
Right arrow Articles by KRISHNAN, K. R. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by LURIE, S. N.
Right arrow Articles by KRISHNAN, K. R. R.

In Vivo Assessment of Pituitary Gland Volume with Magnetic Resonance Imaging: The Effect of Age*

S. N. LURIE, P. M. DORAISWAMY, M. M. HUSAIN, O. B. BOYKO, E. H. ELLINWOOD, G. S. FIGIEL, JR. and K. R. R. KRISHNAN

Duke University Medical Center Durham, North Carolina 27710

Address requests for reprints to: K. R. R. Krishnan, M.D., Box 3215, Duke University Medical Center, Durham, North Carolina 27710.

We used sagittal and coronal Tl weighted magnetic resonance images, at 1.5 Tesla, to measure the height, width, length, and cross-sectional area and to generate two estimates of pituitary gland volume in 35 normal volunteers aged 26–79 yr (19 females and 16 males). Subjects over 50 yr of age had significantly smaller pituitary gland height (P = 0.03), area (P = 0.04), and volume (P = 0.04) than those under 50 yr (by two-tailed t test). Overall, age was negatively correlated with pituitary volume (V1: r = –0.51; P = 0.003; V2: r = –0.47; P = 0.008), area (r = –0.43; P = 0.009), and height (r = –0.46; P = 0.005), but not with pituitary length or width. There were no statistically significant differences in pituitary size between men and women (by two-tailed t test). These findings suggest that pituitary gland height provides a good single measure for the assessment of pituitary gland size and that age must be controlled for in studies of pituitary gland size.

* This work was supported in part by NIMH-MH 42210.

Received December 29, 1989.




This article has been cited by other articles:


Home page
J PsychopharmacolHome page
C. M. Pariante
Pituitary volume in psychosis: the first review of the evidence
J Psychopharmacol, March 1, 2008; 22(2_suppl): 76 - 81.
[Abstract] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
A. M. Fink, S. Vidmar, S. Kumbla, C. C. Pedreira, S. Kanumakala, C. Williams, J. B. Carlin, and F. J. Cameron
Age-Related Pituitary Volumes in Prepubertal Children with Normal Endocrine Function: Volumetric Magnetic Resonance Data
J. Clin. Endocrinol. Metab., June 1, 2005; 90(6): 3274 - 3278.
[Abstract] [Full Text] [PDF]


Home page
Br. J. PsychiatryHome page
C. M. Pariante, K. Vassilopoulou, D. Velakoulis, L. Phillips, B. Soulsby, S. J. Wood, W. Brewer, D. J. Smith, P. Dazzan, A. R. Yung, et al.
Pituitary volume in psychosis
The British Journal of Psychiatry, July 1, 2004; 185(1): 5 - 10.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
P. Chanson, F. Daujat, J. Young, A. Bellucci, M. Kujas, D. Doyon, and G. Schaison
Normal Pituitary Hypertrophy as a Frequent Cause of Pituitary Incidentaloma: A Follow-Up Study
J. Clin. Endocrinol. Metab., July 1, 2001; 86(7): 3009 - 3015.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Neuroradiol.Home page
R. A. Murray, H. G. Maheshwari, E. J. Russell, and G. Baumann
Pituitary Hypoplasia in Patients with a Mutation in the Growth hormone-releasing Hormone Receptor Gene
AJNR Am. J. Neuroradiol., April 1, 2000; 21(4): 685 - 689.
[Abstract] [Full Text]


Home page
RadiologyHome page
T. Shimono, H. Hatabu, K. Kasagi, Y. Miki, S. Nishizawa, T. Misaki, A. Hiraga, and J. Konishi
Rapid Progression of Pituitary Hyperplasia in Humans with Primary Hypothyroidism: Demonstration with MR Imaging
Radiology, November 1, 1999; 213(2): 383 - 388.
[Abstract] [Full Text]


Home page
Am. J. Neuroradiol.Home page
K. Takano, H. Utsunomiya, H. Ono, M. Ohfu, and M. Okazaki
Normal Development of the Pituitary Gland: Assessment with Three-dimensional MR Volumetry
AJNR Am. J. Neuroradiol., February 1, 1999; 20(2): 312 - 315.
[Abstract] [Full Text]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1990 by The Endocrine Society