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Journal of Clinical Endocrinology & Metabolism, Vol 66, 230-232, Copyright © 1988 by Endocrine Society


ARTICLES

High serum progesterone in hyperthyroid men with Graves' disease

K Nomura, H Suzuki, M Saji, N Horiba, M Ujihara, T Tsushima, H Demura and K Shizume
Department of Medicine, Tokyo Women's Medical College, Japan.

We measured serum progesterone in five men with hyperthyroidism due to Graves' disease. All had elevated serum progesterone levels before treatment with an antithyroid drug, and their serum progesterone levels declined concomitantly with their serum thyroid levels during treatment. Progesterone enhances estrogen's stimulation of mammary gland growth, and our findings suggest that progesterone may play a role in the gynecomastia that occurs in men with hyperthyroidism.


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W B Chan, V T F Yeung, C C Chow, W Y So, and C S Cockram
Gynaecomastia as a presenting feature of thyrotoxicosis
Postgrad. Med. J., April 1, 1999; 75(882): 229 - 231.
[Abstract] [Full Text]




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