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Journal of Clinical Endocrinology & Metabolism, Vol 62, 1065-1069, Copyright © 1986 by Endocrine Society

ARTICLES

Ectopic prolactinoma in a patient with hyperparathyroidism and abnormal sellar radiography

Y Shenker, RV LLoyd, L Weatherbee, FK Port, RJ Grekin and AL Barkan

In a patient with hyperparathyroidism and chronic renal failure due to polycystic kidney disease, a finding of destroyed sellar and parasellar structures and hyperprolactinemia suggested the diagnosis of invasive pituitary prolactinoma. At surgery no tumor was found, and pathological examination of the sphenoid bone revealed a parathyroid bone lesion (brown tumor) as well as ectopic prolactinoma in the clivus. This patient demonstrates that a tumor may develop in ectopic pituitary tissue. The combination of radiographically abnormal sellar structures with pituitary hormone hypersecretion should not be regarded as absolute proof of a pituitary adenoma.


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R. M. Pluta, L. Nieman, J. L. Doppman, J. C. Watson, N. Tresser, D. A. Katz, and E. H. Oldfield
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[Abstract] [Full Text]


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