help button home button Endocrine Society JCEM JCEM Call for Nominations for EIC
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS

This Article
Right arrow Submit a related Letter to the Editor
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mak, R. H.
Right arrow Articles by Chantler, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mak, R. H.
Right arrow Articles by Chantler, C.

Journal of Clinical Endocrinology & Metabolism, Vol 60, 229-233, Copyright © 1985 by Endocrine Society


ARTICLES

The influence of hyperparathyroidism on glucose metabolism in uremia

RH Mak, A Bettinelli, C Turner, GB Haycock and C Chantler

We studied glucose metabolism in a group of adolescents and young adults with uremia using the hyperglycemic clamp technique. In eight adolescent patients, the glucose metabolic rate correlated negatively with PTH levels and positively with the glomerular filtration rate. Six patients, one adolescent and five adults on regular hemodialysis with severe hyperparathyroidism, had low glucose metabolic rates and reduced insulin sensitivity compared to normal subjects. After parathyroidectomy, the glucose metabolic rate improved by 47%; plasma insulin concentrations during hyperglycemia increased by 37%, and insulin sensitivity did not change significantly. Thus, correction of hyperparathyroidism was associated with normalization of glucose metabolic rates and increased insulin secretion, but insulin resistance did not change.


This article has been cited by other articles:


Home page
NDT PlusHome page
M. Cozzolino, A. Galassi, M. Gallieni, and D. Brancaccio
Successful use of low-dose intravenous paricalcitol in the treatment of severe secondary hyperparathyroidism in a haemodialysis patient
NDT Plus, June 1, 2008; 1(3): 148 - 150.
[Full Text] [PDF]


Home page
Eur J EndocrinolHome page
T. Reinehr, G. de Sousa, U. Alexy, M Kersting, and W. Andler
Vitamin D status and parathyroid hormone in obese children before and after weight loss
Eur. J. Endocrinol., August 1, 2007; 157(2): 225 - 232.
[Abstract] [Full Text] [PDF]


Home page
J. Am. Soc. Nephrol.Home page
L. Cuppari, A. B. de Carvalho, C. M. Avesani, M. A. Kamimura, R. R. dos Santos Lobao, and S. A. Draibe
Increased Resting Energy Expenditure in Hemodialysis Patients with Severe Hyperparathyroidism
J. Am. Soc. Nephrol., November 1, 2004; 15(11): 2933 - 2939.
[Abstract] [Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1985 by The Endocrine Society