Journal of Clinical Endocrinology & Metabolism, Vol 59, 806-808, Copyright © 1984 by Endocrine Society

ARTICLES

Hormonal influences on the secretion of steroid-binding proteins by a human hepatoma-derived cell line

W Rosner, DP Aden and MS Khan

We examined the influence of numerous substances on the secretion of corticosteroid-binding globulin (CBG) and testosterone-estradiol binding globulin (TeBG) by a human hepatoma-derived cell line. Thyroxine, at physiologic concentrations, resulted in an increased secretion of TeBG but not CBG. Estrogens, antiestrogens, and androgens were without effect on either of these binding proteins.

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