| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
Journal of Clinical Endocrinology & Metabolism, Vol 56, 1332-1334, Copyright © 1983 by Endocrine Society
ARTICLES |
ES Koay, CK Too, FC Greenwood and GD Bryant-Greenwood
Dispersed cells from human amnion and chorion were cultured with and without relaxin. The addition of this hormone caused an increased secretion of both collagenase and plasminogen activator into the culture medium over a 32 h period, but had no effect on proteoglycanase or beta-glucuronidase secretion. The increase in plasminogen activator was dose-related to the amount of relaxin added in vitro. The results show that the fetal membranes are a novel target tissue for relaxin in the human, and suggest that relaxin in vivo may cause a similar release of collagenolytic enzymes, leading to the weakening and eventual rupture of the fetal membranes.
This article has been cited by other articles:
![]() |
G. D. Bryant-Greenwood, A. Kern, S. Y. Yamamoto, D. W. Sadowsky, and M. J. Novy Relaxin and the Human Fetal Membranes Reproductive Sciences, December 1, 2007; 14(8_suppl): 42 - 45. [Abstract] [PDF] |
||||
![]() |
J. L. Dragoo, R. S. Lee, P. Benhaim, G. A. M. Finerman, and S. L. Hame Relaxin Receptors in the Human Female Anterior Cruciate Ligament Am. J. Sports Med., July 1, 2003; 31(4): 577 - 584. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. D. Bryant-Greenwood and L. K. Millar Human Fetal Membranes: Their Preterm Premature Rupture Biol Reprod, December 1, 2000; 63(6): 1575b - 1579. [Abstract] [Full Text] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Endocrinology | Endocrine Reviews | J. Clin. End. & Metab. |
| Molecular Endocrinology | Recent Prog. Horm. Res. | All Endocrine Journals |