help button home button Endocrine Society JCEM JCEM Call for Nominations for EIC
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Submit a related Letter to the Editor
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shinkawa, O.
Right arrow Articles by Tachibana, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shinkawa, O.
Right arrow Articles by Tachibana, Y.

Journal of Clinical Endocrinology & Metabolism, Vol 56, 1327-1331, Copyright © 1983 by Endocrine Society

ARTICLES

Changes of serum gonadotropin levels and sex differences in premature and mature infant during neonatal life

O Shinkawa, N Furuhashi, T Fukaya, M Suzuki, H Kono and Y Tachibana

We measured FSH and LH concentrations by RIA in 130 cord sera and 213 peripheral sera obtained as serially as possible from 67 infants who were 5-75 days old and were born between the 28th and 42nd gestational weeks. Cord serum FSH and LH (+hCG) levels were 3.9-13.6 mIU/ml and 43.3-88.6 mIU/ml, respectively; they decreased with advancing gestational age. Postnatal FSH levels in male infants maintained low levels (3.7-8.7 mIU/ml). However, those in female infants increased with peak levels (51.8-270.3 mIU/ml) between 11 and 30 days after delivery, and then decreased; the surge was more marked and prolonged in preterm infants than in term infants. Postnatal LH levels in both sexes decreased rapidly after birth, which may be due to a decrease of placental hCG, and thereafter displayed patterns similar to FSH levels. We found a significant sex difference of serum gonadotropin levels in newborn infants and differences between term and preterm infants. Our results suggest that the sex difference of pituitary gonadal function exists and that the function matures during the fetal and neonatal life.


This article has been cited by other articles:


Home page
 PediatricsHome page
R. F. Greaves, R. W. Hunt, A. S. Chiriano, and M. R. Zacharin
Luteinizing Hormone and Follicle-Stimulating Hormone Levels in Extreme Prematurity: Development of Reference Intervals
Pediatrics, March 1, 2008; 121(3): e574 - e580.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
I. Bergada, C. Milani, P. Bedecarras, L. Andreone, M. G. Ropelato, S. Gottlieb, C. Bergada, S. Campo, and R. A. Rey
Time Course of the Serum Gonadotropin Surge, Inhibins, and Anti-Mullerian Hormone in Normal Newborn Males during the First Month of Life
J. Clin. Endocrinol. Metab., October 1, 2006; 91(10): 4092 - 4098.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
C.A. Williams, M.R. Wallace, K.C. Drury, S. Kipersztok, R.K. Edwards, R.S. Williams, M.J. Haller, D.A. Schatz, J.H. Silverstein, B.A. Gray, et al.
Blood lymphocyte chimerism associated with IVF and monochorionic dizygous twinning: Case report
Hum. Reprod., December 1, 2004; 19(12): 2816 - 2821.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
C. Bouvattier, J.-C. Carel, C. Lecointre, A. David, C. Sultan, A.-M. Bertrand, Y. Morel, and J.-L. Chaussain
Postnatal Changes of T, LH, and FSH in 46,XY Infants with Mutations in the AR Gene
J. Clin. Endocrinol. Metab., January 1, 2002; 87(1): 29 - 32.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1983 by The Endocrine Society