help button home button Endocrine Society JCEM JCEM Call for Nominations for EIC
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Submit a related Letter to the Editor
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Vining, R. F.
Right arrow Articles by Rice, B. V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Vining, R. F.
Right arrow Articles by Rice, B. V.

Journal of Clinical Endocrinology & Metabolism, Vol 56, 454-460, Copyright © 1983 by Endocrine Society

ARTICLES

Saliva estriol measurements: an alternative to the assay of serum unconjugated estriol in assessing feto-placental function

RF Vining, R McGinley and BV Rice

We have investigated the possibility of replacing measurements of maternal serum estriol (E3) with maternal saliva E3. Saliva and serum E3 concentrations were measured by RIA in samples obtained from normal subjects in late pregnancy. The saliva E3 was found to accurately reflect the serum unbound unconjugated E3 and was directly proportional to total serum unconjugated E3. The variability in saliva E3, as assessed by the coefficient of variation for samples collected at intervals of 1 day, 1 h, or 10 min (16.5%, 22.7%, and 13.1% respectively) was not significantly different from published data on the variability in serum E3. No diurnal variation was apparent in samples collected every hour throughout the waking period of a normal day (n = 23). The increase in saliva E3 with gestational age was consistent with the well established pattern for serum E3, with the median value exhibiting a small but significant rise between 32 and 33 weeks and a larger rise between 36 and 37 weeks. The ease with which saliva samples may be collected procedure together with the high correlation between saliva and serum unconjugated E3 levels suggest that assay of saliva E3 should replace serum E3 measurement for assessing feto-placental wellbeing.


This article has been cited by other articles:


Home page
 Ann. N. Y. Acad. Sci.Home page
C. LU, T. RODRIGUEZ, A. FUNEZ, R. S IRISH, and R. A FENSKE
The assessment of occupational exposure to diazinon in nicaraguan plantation workers using saliva biomonitoring.
Ann. N.Y. Acad. Sci., September 1, 2006; 1076: 355 - 365.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
J. B. Becker, A. P. Arnold, K. J. Berkley, J. D. Blaustein, L. A. Eckel, E. Hampson, J. P. Herman, S. Marts, W. Sadee, M. Steiner, et al.
Strategies and Methods for Research on Sex Differences in Brain and Behavior
Endocrinology, April 1, 2005; 146(4): 1650 - 1673.
[Abstract] [Full Text] [PDF]

Home page
 Crit. Rev. Oral Biol. Med.Home page
E. Kaufman and I. B. Lamster
THE DIAGNOSTIC APPLICATIONS OF SALIVA-- A REVIEW
Crit. Rev. Oral. Biol. Med., March 1, 2002; 13(2): 197 - 212.
[Abstract] [Full Text]

Home page
 J. Nutr.Home page
L. F. Hofman
Human Saliva as a Diagnostic Specimen
J. Nutr., May 1, 2001; 131(5): 1621S - 1625.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1983 by The Endocrine Society