help button home button Endocrine Society JCEM JCEM Call for Nominations for EIC
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Submit a related Letter to the Editor
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Khokher, M. A.
Right arrow Articles by Dandona, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Khokher, M. A.
Right arrow Articles by Dandona, P.

Journal of Clinical Endocrinology & Metabolism, Vol 56, 393-396, Copyright © 1983 by Endocrine Society

ARTICLES

Insulin-like stimulatory effect of Fc fragments of human immunoglobulin G on rat adipocyte lipogenesis: indirect evidence for Fc receptor on adipocytes

MA Khokher and P Dandona

We have recently shown that human immunoglobulin G (IgG) exerts an insulin-like stimulatory effect on lipogenesis by rat and human adipocytes in vitro. Highly purified polyclonal IgGs prepared from normal subjects have stimulatory potencies similar to those of monoclonal IgGs obtained from patients with hIgG myeloma. These observations suggest that this effect is probably exerted by a nonspecific nonvariable portion of the IgG molecule. We now present data to show that the Fc moiety of the IgG molecule is responsible for the stimulatory effect of this IgG molecule. These data also provide evidence for the first time that adipocytes may have Fc receptors.


This article has been cited by other articles:


Home page
 ANGIOLOGYHome page
V. Fonseca, D.P. Mikhailidis, F. Boag, M.A. Barradas, J.Y. Jeremy, L. Gracey, and P. Dandona
Thrombocytopenia and Lupus-Like Anticoagulant in a Patient with Peripheral Vascular Disease: Response to Infusion of Prostacyclin
Angiology, April 1, 1985; 36(4): 258 - 263.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1983 by The Endocrine Society