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Anterior Mediastinal Mass in a Patient with Graves' Disease^*

THOMAS A. BERGMAN, CARY N. MARIASH and JACK H. OPPENHEIMER

Division of Endocrinology and Metabolism, Department of Medicine, University of Minnesota Minneapolis, Minnesota 55455

To whom correspondence and requests for reprints should be addressed.

The finding of hyperplastic lymphoid tissue in patients with Graves' disease is not uncommon. However, massive thymic enlargement is quite rare. In this report we present evidence that a massively enlarged thymus in a patient with Graves' disease returned to normal upon institution of propylthiouracil therapy. We suggest that a potential response to antithyroid therapy must be considered before recommending invasive procedures.

^* This work was supported in part by NIH Grant AM-19812 (to J.H.O.) and Clinical Investigative Award AM-00800 (to C.N.M.).

Received March 11, 1982.

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