help button home button Endocrine Society JCEM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Submit a related Letter to the Editor
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ehrenkranz, J. R.
Right arrow Articles by Cutler, G. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ehrenkranz, J. R.
Right arrow Articles by Cutler, G. B., Jr

Journal of Clinical Endocrinology & Metabolism, Vol 55, 307-310, Copyright © 1982 by Endocrine Society

ARTICLES

Daily rhythm of plasma melatonin in normal and precocious puberty

JR Ehrenkranz, L Tamarkin, F Comite, RE Johnsonbaugh, DE Bybee, DL Loriaux and GB Cutler Jr

A previous study of normal humans has shown a decrease in plasma melatonin at the onset of puberty, suggesting that melatonin may act to restrain pubertal onset. We have measured plasma melatonin throughout a 24-h period in normal and constitutionally short males at different pubertal stages and in patients with idiopathic true precocious puberty and familial male isosexual precocity. The 24-h profile of plasma melatonin was similar for the prepubertal, pubertal, and adult males studied, with all subjects having low levels (20-50 pg/ml) during the day and high levels (80-100 pg/ml) at night between 0100-0500 h. The 24- h profiles of the patients with isosexual precocity were similar to the profiles observed throughout normal puberty. These data do not support a role for melatonin in the initiation of normal or precocious puberty in man.


This article has been cited by other articles:


Home page
 J. Clin. Endocrinol. Metab.Home page
E. Leibenluft, P. J. Schmidt, E. H. Turner, M. A. Danaceau, S. B. Ashman, T. A. Wehr, and D. R. Rubinow
Effects of Leuprolide-Induced Hypogonadism and Testosterone Replacement on Sleep, Melatonin, and Prolactin Secretion in Men
J. Clin. Endocrinol. Metab., October 1, 1997; 82(10): 3203 - 3207.
[Abstract] [Full Text] [PDF]

Home page
 J Biol RhythmsHome page
H. Underwood and B. D. Goldman
Vertebrate Circadian and Photoperiodic Systems: Role of the Pineal Gland and Melatonin
J Biol Rhythms, December 1, 1987; 2(4): 279 - 315.
[PDF]

Home page
 J PsychopharmacolHome page
S.A. Checkley and S.B.G. Park
The psychopharmacology of the human pineal
J Psychopharmacol, January 1, 1987; 1(2): 109 - 125.
[Abstract] [PDF]

Home page
 ScienceHome page
L Tamarkin, C. Baird, and O. Almeida
Melatonin: a coordinating signal for mammalian reproduction?
Science, February 15, 1985; 227(4688): 714 - 720.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1982 by The Endocrine Society