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Journal of Clinical Endocrinology & Metabolism, Vol 54, 470-473, Copyright © 1982 by Endocrine Society

ARTICLES

Normal cortical bone mass in patients after long term coumadin therapy

LD Piro, MP Whyte, WA Murphy and SJ Birge

Clinical delineation of the warfarin embryopathy and the recent discovery of osteocalcin (a vitamin K-dependent bone protein) suggest that coumadin therapy could adversely affect the skeleton. Using bone densitometry and metacarpal cortical width measurement, we found normal cortical bone mass in 17 adults receiving long term coumadin therapy.


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