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Journal of Clinical Endocrinology & Metabolism, Vol 53, 109-102, Copyright © 1981 by Endocrine Society

ARTICLES

Effects of thyrotropin-releasing hormone and metoclopramide in patients with phenothiazine-induced hyperprolactinemia

HV Lankford, WG Blackard, DF Gardner and HS Tucker

TRH and metoclopramide tests were performed in 10 female patients with presumed phenothiazine-induced hyperprolactinemia to define the serum PRL response to these agents. Our results show that the serum PRL response to metoclopramide is blunted in most patients with phenothiazine-induced hyperprolactinemia, and the serum PRL response to TRH is exaggerated in most patients during and 3 weeks after stopping phenothiazines.




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Copyright © 1981 by The Endocrine Society