This Article Full Text (PDF) Submit a related Letter to the Editor Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Copyright Permission Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by ERTAN, A. Articles by ARIMURA, A. Search for Related Content PubMed PubMed Citation Articles by ERTAN, A. Articles by ARIMURA, A.

IMMUNOREACTIVE SOMATOSTATIN IN HUMAN PANCREATIC SECRETION

Department of Medicine, Tulane University School of Medicine, and Veterans Administration Medical Center New Orleans, Louisiana 70112

Address for reprint requests: K. Akdamar, MD, Chief of the GI Section, 1430 Tulane Ave., New Orleans, Louisiana 70112

Somatostatin in human pancreatic juice collected during endoscopic retrograde cholangiopancreatography following secretin injection was determined by RIA. The mean immunoreactive somatostatin (IRS) levels in the pancreatic juice of 13 non-diabetics was 78± 11 (SE) pg/ml. The IRS levels in 4 non-insulin-dependent diabetics ranged from 843 to 2286 pg/ml with a mean of 1559 ^± 392 (SE) pg/ml. This was significantly greater than non-diahetic values.The IRS in the pancreatic juice was immunologically indistinguishable from somatostatin¹⁴but consisted of 2 major components, one corresponding to somatostatin ¹⁴ and the other being of a molecular size of approximately 3000 daltons.

Received October 20, 1980.

This article has been cited by other articles:

				E. Bertelli and M. Bendayan Association between Endocrine Pancreas and Ductal System. More than an Epiphenomenon of Endocrine Differentiation and Development? J. Histochem. Cytochem., September 1, 2005; 53(9): 1071 - 1086. [Abstract] [Full Text] [PDF]