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Journal of Clinical Endocrinology & Metabolism, Vol 51, 252-253, Copyright © 1980 by Endocrine Society

ARTICLES

Medullary carcinoma of the thyroid before age 2 years

MR Stjernholm, JC Freudenbourg, HS Mooney, FJ Kinney and LJ Deftos

An 18-month-old infant was evaluated for medullary thyroid carcinoma (MTC) because of a maternal history of the tumor and the presence of characteristic mucosal abnormalities. Although examination of the thyroid gland was normal, RIA of plasma calcitonin reveled elevated basal levels of the hormone and the patient underwent total thyroidectomy at 23 months of age. Histological examination of the tumor was consistent with the diagnosis f MTC, and this diagnosis was confirmed by immunohistology. The earliest feasible evaluation for MTC should be performed in children of an affected family.


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