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Journal of Clinical Endocrinology & Metabolism, Vol 50, 867-869, Copyright © 1980 by Endocrine Society

ARTICLES

Normal integrated concentration of aldosterone and plasma renin activity: effect of age

Z Zadik and AA Kowarski

The integrated concentration of aldosterone (IC-ALDO) and PRA (IC-PRA) was studied in 78 normal subjects ranging in age from 9--50 yr. Whereas the IC-ALDO to IC-PRA were found to decrease with age, the ratio of IC- ALDO to IC-PRA was not affected by age. A significant lowering of the normal range and variance was achieved by measuring the 24-h integrated concentration instead of the concentration in discrete samples.




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