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Journal of Clinical Endocrinology & Metabolism, Vol 48, 736-738, Copyright © 1979 by Endocrine Society

ARTICLES

Urinary follicle-stimulating hormone during pregnancy: relationship to sex of fetus

HE Kulin, SJ Santner and WJ Mann

FSH excretion was determined by RIA in 111 urine samples from 23 pregnant women. The use of acetone extraction allowed a 20-fold concentration of urine and the accurate quantitation of hormone levels. Between 10 weeks of gestation and term, FSH secretion was consistently low, with a mean excretion of 18 mIU/h; this amount compares to levels found in other states of marked hCG excess (e.g. choriocarcinoma) and is considerably less than the FSH excretion by prepubertal children. Maternal levels of urinary FSH did not differ with sex, suggesting a primary maternal pituitary origin for pregnancy FSH.




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Copyright © 1979 by The Endocrine Society