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Journal of Clinical Endocrinology & Metabolism, Vol 47, 204-207, Copyright © 1978 by Endocrine Society


ARTICLES

Lack of arginine vasopressin response to central dopamine blockade in normal adults

KS Kendler, RE Weitzman and RT Rubin

Haloperidol, a central nervous system dopamine blocker, was given im to seven normal volunteers at a dose level (1.0 mg) known to have central nervous system effects. Plasma PRL levels rose sharply in response to haloperidol, but plasma arginine vasopressin levels did not change significantly. These data do not support the hypothesis of a prominent dopamine neurotransmitter regulation of arginine vasopressin secretion.


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R. J. Goldberg
Selective Serotonin Reuptake Inhibitors: Infrequent Medical Adverse Effects
Arch Fam Med, January 1, 1998; 7(1): 78 - 84.
[Abstract] [Full Text] [PDF]




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