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Journal of Clinical Endocrinology & Metabolism, Vol 46, 698-701, Copyright © 1978 by Endocrine Society

ARTICLES

Transitory hCG-like activity in the urine of some IUD users

GD Hodgen, HC Chen, ML Dufau, TA Klein and DR Mishell

Using an antiserum (H-93) specific to the COOH-terminal peptide of hCG beta and gel chromatography, we found the transitory (1-2 days) presence of a gonadotropin having immunological, biological, and physical similarity to hCG, but not typical hLH, in the late luteal phase (days 24-29) urine of some (5 of 26) IUD users. We did not detect hCG in sera from any of the women. Although the source of the hCG-like gonadotropin is unknown, the data suggest that late luteal phase implantation may have occurred transiently.




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Copyright © 1978 by The Endocrine Society