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Journal of Clinical Endocrinology & Metabolism, Vol 46, 689-690, Copyright © 1978 by Endocrine Society

ARTICLES

Effect of LRH on gonadotropin secretion in newborn male infants

G Delitala, T Meloni, A Masala, S Alagna, L Devilla and R Corti

The concentrations of LH and FSH were measured in eight male newborn babies, aged 4-6 h, before and after the administration of 25 micrograms synthetic LHR. A comparison was performed with six control newborns receiving normal saline. Both LH and FSH rose significantly in all subjects after LHR administration. Their values were significantly higher than those observed during the control study. These data demonstrate sensitivity of the pituitary gonadotropes to synthetic LHR and a pubertal-type response to LH in the early hours of human life.




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Copyright © 1978 by The Endocrine Society