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Journal of Clinical Endocrinology & Metabolism, Vol 45, 1205-1210, Copyright © 1977 by Endocrine Society

ARTICLES

Cushing's syndrome associated with galactorrhea, amenorrhea, and hypothyroidism: a primary hypothalamic disorder

FG Berlinger, HJ Ruder and JF Wilber

A 19-year-old woman presented with a unique constellation of endocrinopathies, including Cushing's disease, post-partum galactorrhea, hypothalamic hypothyroidism and hypothalamic amenorrhea. There was no evidence of granulomatous or neoplastic disease in pituitary or hypothalamus. The potential role of excess glucocorticoids and disturbances in normal hypothalamic regulation of anterior pituitary function in the pathophysiology of this syndrome is discussed.




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Copyright © 1977 by The Endocrine Society