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Journal of Clinical Endocrinology & Metabolism, Vol 45, 1108-1111, Copyright © 1977 by Endocrine Society

ARTICLES

Radioimmunoassay of human beta-lipotropin in unextracted plasma

E Wiedemann, T Saito, JA Linfoot and CH Li

A sensitive and specific radioimmunoassay for human beta-lipotropin (betah-LPH) in unextracted plasma was developed using pur betah-LPH as tracer and standard and an antiserum not cross-reacting with human beta- MSH and hACTH. In healthy volunteers plasma betah-LPH ranged from less than 20 to 150 pg/ml at 8:00 a.m. and rose after metyrapone administration. betah-LPH was very low in panhypopituitarism, normal in most patients with untreated Cushing's disease, elevated in acromegaly and extremely high in Nelson's syndrome.


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D. Carr, R Bergland, A Hamilton, H Blume, N Kasting, M Arnold, J. Martin, and M Rosenblatt
Endotoxin-stimulated opioid peptide secretion: two secretory pools and feedback control in vivo
Science, August 27, 1982; 217(4562): 845 - 848.
[Abstract] [PDF]


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