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Journal of Clinical Endocrinology & Metabolism, Vol 45, 853-856, Copyright © 1977 by Endocrine Society

ARTICLES

Relation between growth hormone levels and Von Willebrand factor activity

KE Sarji, JH Levine, RM Nair, J Sagel and JA Colwell

The relationship between growth hormone and von Willebrand factor activity was studied in fasting plasma samples, nocturnal samples, and after intramuscular injection of growth hormone. A significant correlation was seen between the two levels in fasting samples. During sleep, peaks of growth hormone were associated with peaks of von Willebrand factor activity. A subject with isolated growth hormone deficiency had no peaks of either. Intramuscular injection of growth hormone produced a rise of von Willebrand factor activity in all subjects studied. These results indicate that there is a relationship between growth hormone and von Willebrand factor activity.


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