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Journal of Clinical Endocrinology & Metabolism, Vol 45, 576-578, Copyright © 1977 by Endocrine Society

ARTICLES

Elevated basal growth hormone levels and growth hormone response to TRH in alcoholic patients with cirrhosis

A Zanoboni and W Zanoboni-Muciaccia

Basal plasma growth hormone (GH) and GH responses after the administration of thyrotropin releasing hormone (TRH) were studied in 9 male alcoholic patients with cirrhosis. Basal GH was significantly higher in cirrhotic patients than in normal men. Intravenous injection of synthetic TRH (400 microgram) caused a significant increase in plasma GH in 7 out of the 9 cirrhotic patients examined, while it did not increase GH levels in normal subjects.




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Copyright © 1977 by The Endocrine Society