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Journal of Clinical Endocrinology & Metabolism, Vol 45, 363-366, Copyright © 1977 by Endocrine Society

ARTICLES

A specific and rapid determination of human skin dihydrotestosterone cytosol receptor

D Evain, NO Savage and E Binet

The 5 alpha-Dihydrotestosterone (DHT) receptor in cytosol prepared from foreskin fragments was identified and measured by polyacrylamide gel electrophoresis (PAGE). 14 normal subjects, 4 boys with hypospadias and two patients with male pseudohermaphroditism (MPH) were studied. The amount of DHT receptor was comparable in the normal subjects and those with hypospadias. No receptor was found in the 2 cases of MPH.




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Copyright © 1977 by The Endocrine Society