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Journal of Clinical Endocrinology & Metabolism, Vol 45, 134-140, Copyright © 1977 by Endocrine Society

ARTICLES

Growth hormone and prolactin responses to thyrotropin-releasing hormone in patients with severe liver disease

AE Panerai, F Salerno, M Manneschi, D Cocchi and EE Muller

Thyrotropin-releasing hormone (TRH) was administered iv to 10 patients with severe liver disease and 10 control subjects. Injection of 400 microgram TRH as a bolus induced in 7 out of 10 patients a clear-cut GH rise (larger than or equal 10 ng/ml) occurring 15-120 min after the injection, and no effect on GH levels in controls. Mean baseline GH levels wre higher in patients than in controls. An exaggerated and sustained PRL rise was present after TRH in the subjects with liver disease, whose mean baseline plasma PRL levels were within normal range.


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Th. Kaltsas, N. Pontikides, G.E. Krassas, K. Seferiadis, D. Lolis, and I.E. Messinis
Growth hormone response to thyrotrophin releasing hormone in women with polycystic ovarian syndrome
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[Abstract] [Full Text] [PDF]


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