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Journal of Clinical Endocrinology & Metabolism, Vol 44, 1222-1225, Copyright © 1977 by Endocrine Society

ARTICLES

Effect of prolactin on plasma DHEA (s) levels

A Vermeulen, E Suy and R Rubens

Plasma DHEA and DHEA-S levels were significantly higher (P less than 0.001) in women with elevated prolactin levels, due either to chronic treatment with psychotropic drugs or to a prolactinoma, than in untreated controls. This increase was also observed in 3 male patients with prolactinoma. It is suggested that this increase is the consequence of a direct effect of prolactin on the adrenal cortex and that prolactin might be responsible for the ACTH independent andrenocortical androgen secretion.




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Copyright © 1977 by The Endocrine Society