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Journal of Clinical Endocrinology & Metabolism Vol. 44, No. 6 1107-1114
doi:10.1210/jcem-44-6-1107
Copyright © 1977 by the Endocrine Society.
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Thyroid Function Tests During the Early Phase of Subacute Thyroiditis

ALBERT C. WEIHL, GILBERT H. DANIELS*, E. CHESTER RIDGWAY and FARAHE MALOOF

Thyroid Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114

* Reprint requests to: Dr. Daniels, Thyroid Unit, Massachusetts General Hospital, Boston, Massachusetts 02114.

Six patients with subacute thyroditis were followed with serial measurements of T4, FT4) TSH and RAI uptake. Five of the six underwent TRH stimulation early in the course of their illness. All six patients had elevated or high normal values for T4 and FT4 at the time of their clinical presentation (mean = 13.8 µg per 100 ml and 3.9 ng per 100 ml, respectively). RAI uptakes were 1% or less in all six. TRH testing revealed a suppressed TSH response (mean =TSH ±0.1 µU/ml) in all five patients tested, suggesting hyperthyroidism. After initial studies were performed, five patients were treated with L-triiodothyronine (L-T3) and one with aspirin. All patients improved over a two to four week period of time, no relapses being noted.

Supported in part by USPHS grants AM-16791 and AM-04501.

Received July 2, 1976.




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