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Journal of Clinical Endocrinology & Metabolism, Vol 44, 206-209, Copyright © 1977 by Endocrine Society

ARTICLES

Decreased binding of insulin by receptors on placental membranes from diabetic mothers

LC Harrison, T Billington, S Clark, R Nichols, I East and FI Martin

Specific binding of insulin to microsomal membranes from the placentae of insulin-dependent diabetics was significantly decreased when compared with normals. This was due to an apparent decrease in the concentration of insulin receptors.


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T. Robinson, J. Archer, K. Gambhir, V. Hollis Jr, L Carter, and C Bradley
Erythrocytes: a new cell type for the evaluation of insulin receptor defects in diabetic humans
Science, July 13, 1979; 205(4402): 200 - 202.
[Abstract] [PDF]


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Copyright © 1977 by The Endocrine Society