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Journal of Clinical Endocrinology & Metabolism, Vol 44, 196-198, Copyright © 1977 by Endocrine Society

ARTICLES

The effect of dopamine infusion on insulin and glucagon secretion in man

H Leblanc, GC Lachelin, S Abu-Fadil and SS Yen

The effect of dopamine on the release of insulin and glucagon was investigated in eight adult subjects. Dopamine infused iv at a rate of 4 mug/kg/min X 2 hr, unaccompanied by cardiovascular changes, induced a prompt and significant increase in plasma insulin and glucagon and in plasma glucose levels. These findings suggest that dopamine may stimulate both alpha and beta cells.




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Endocrinology Endocrine Reviews J. Clin. End. & Metab.
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Copyright © 1977 by The Endocrine Society