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Journal of Clinical Endocrinology & Metabolism, Vol 43, 704-707, Copyright © 1976 by Endocrine Society


ARTICLES

Measurement of glucose turnover in the human newborn with glucose-1-13C

SC Kalhan, SM Savin and PA Adam

Systemic glucose production rates were measured in 6 normal newborn infants by dilution of glucose-1-13C tracer according to the prime constant-rate infusion technique. Glucose production rates were 4.4 +/- 0.39 mg/kg. min. (Mean +/- S.D.) in 4 infants at 2 hours of age, and were 3.83 and 3.86 mg/kg. min. in 2 infants at 1 day of age. Systemic glucose production accounts for 50% of the substrate utilized for oxidative metabolism in newborn infants.





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