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Journal of Clinical Endocrinology & Metabolism, Vol 43, 682-685, Copyright © 1976 by Endocrine Society

ARTICLES

A radioimmunoassay for measurement of 3,3'-L-diiodothyronine (T2)

SY Wu, IJ Chopra, Y Nakamura, DH Solomon and LR Bennett

A sensitive, specific and reproducible radioimmunoassay (RIA) for measurement of 3,3'-L-diiodothyoride (T2) in concentrated ethanol extracts of serum and amniotic fluid is described. The T2 binding antiserum was prepared aby immunization of rabbits with T2-human serum albumin conjugate. Of various thyroid hormone derivatives tested, only 3-L-monoiodothyonine cross-reacted significantly with T2 binding sites on the antiserum...


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