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Journal of Clinical Endocrinology & Metabolism, Vol 43, 240-243, Copyright © 1976 by Endocrine Society

ARTICLES

Actions of growth hormone-release inhibiting hormone (somatostatin) on the renin aldosterone system

A Gomez-Pan, MH Snow, DA Piercy, V Robson, R Wilkinson, R Hall and DC Evered

Administration of growth hormone-release inhibiting hormone (GH-RIH, somatostatin), as a 90 minute infusion (10 mug/min), to 3 healthy young men under conditons of active renin secretion acheived by pretreatment with furosemide (80 mg daily for 5 days), caused a mean 30% fall in plasma renin activity, which returned to basal levels immediately after stopping the GH-RIH infusion. Plasma aldosterone levels were not affected during the course of this experiment.




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Copyright © 1976 by The Endocrine Society