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Journal of Clinical Endocrinology & Metabolism Vol. 43, No. 1 195-197
doi:10.1210/jcem-43-1-195
Copyright © 1976 by the Endocrine Society.
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Gonadotropin and Sex Steroid Response to Luteinizing Hormone-Releasing Hormone in Patients with Premature Adrenarche

PETER A. LEE and FRANK J. GAREIS

Clinical Investigation Center and Department of Pediatrics, Naval Regional Medical Center Oakland, California 94627

Reprint requests to: Publications Office, Clinical Investigation Center, Naval Regional Medical Center, Oakland, California 94627.

Luteinizing hormone-releasing hormone (100 µg IV) produced a response of LH, FSH, testosterone, and estradiol in children with premature pubarche that was not different from that among normal prepubertal children. Hence, this study provides no evidence that hypothalamic-pituitary-gonadal maturation occurs with the onset of premature sexual hair.

Supported by funds from the Bureau of Medicine and Surgery, Navy Department, for CIP 5-48-573C.

The opinions or assertions contained herein are the private ones of the authors and are not to be construed as official or as reflecting the views of the Navy Department or the naval service at large.

Received August 1, 1975.




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Copyright © 1976 by The Endocrine Society