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Journal of Clinical Endocrinology & Metabolism, Vol 43, 195-197, Copyright © 1976 by Endocrine Society

ARTICLES

Gonadotropin and sex steroid response to luteinizing hormone-releasing hormone in patients with premature adrenarche

PA Lee and FJ Gareis

Luteinizing hormone-releasing hormone (100 mug iv) produced a response of LH, FSH, testosterone, and estradiol in children with premature pubarche that was not different from that among normal prepubertal children. Hence, this study provides no evidence that hypothalamic- pituitary-gonadal maturation occurs with the onset of premature sexual hair.


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